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Article: Acupuncture for hypoxic ischemic encephalopathy in neonates

TitleAcupuncture for hypoxic ischemic encephalopathy in neonates
Authors
Issue Date2013
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.mrw.interscience.wiley.com/cochrane/cochrane_clsysrev_articles_fs.html
Citation
Cochrane Database of Systematic Reviews, 2013, v. 1, article no. CD007968 How to Cite?
AbstractHypoxic ischemic encephalopathy (HIE) in the neonate is associated with high mortality and morbidity. Effective treatment options are limited and therefore alternative therapies such as acupuncture are increasingly used. We sought to determine the efficacy and safety of acupuncture on mortality and morbidity in neonates with HIE. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), Cochrane Neonatal Specialized Register, MEDLINE, AMED, EMBASE, PubMed, CINAHL, PsycINFO, WHO International Clinical Trials Registry Platform, and various Chinese medical databases in November 2012. We planned to include randomized or quasi-randomized controlled trials comparing needle acupuncture to a control group that used no treatment, placebo or sham treatment in neonates (less than 28 days old) with HIE. Co-interventions were allowed as long as both the intervention and the control group received the same co-interventions. We excluded trials that evaluated therapy that did not involve penetration of the skin with a needle or trials that compared different forms of acupuncture only. Two review authors independently reviewed trials for inclusion. If trials were identified, the review authors planned to assess trial quality and extract data independently. We planned to use the risk ratio (RR), risk difference (RD), and number needed to benefit (NNTB) or harm (NNTH) with 95% confidence intervals (CI) for dichotomous outcomes, and mean difference (MD) with 95% CI for continuous outcomes. No trial satisfied our predefined inclusion criteria. Existing trials only evaluated acupuncture in older infants who survived HIE. There are currently no randomized controlled trials evaluating the efficacy of acupuncture for treatment of HIE in neonates. The safety of acupuncture for HIE in neonates is unknown. The rationale for acupuncture in neonates with HIE is unclear and the evidence from randomized controlled trial is lacking. Therefore, we do not recommend acupuncture for the treatment of HIE in neonates. High quality randomized controlled trials on acupuncture for HIE in neonates are needed.
DescriptionIntervention Review
Persistent Identifierhttp://hdl.handle.net/10722/183775
ISSN
2014 Impact Factor: 6.035
2015 SCImago Journal Rankings: 2.366
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, Ven_US
dc.contributor.authorCheuk, DKLen_US
dc.contributor.authorChu, Ven_US
dc.date.accessioned2013-06-18T04:13:47Z-
dc.date.available2013-06-18T04:13:47Z-
dc.date.issued2013en_US
dc.identifier.citationCochrane Database of Systematic Reviews, 2013, v. 1, article no. CD007968en_US
dc.identifier.issn1469-493X-
dc.identifier.urihttp://hdl.handle.net/10722/183775-
dc.descriptionIntervention Review-
dc.description.abstractHypoxic ischemic encephalopathy (HIE) in the neonate is associated with high mortality and morbidity. Effective treatment options are limited and therefore alternative therapies such as acupuncture are increasingly used. We sought to determine the efficacy and safety of acupuncture on mortality and morbidity in neonates with HIE. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), Cochrane Neonatal Specialized Register, MEDLINE, AMED, EMBASE, PubMed, CINAHL, PsycINFO, WHO International Clinical Trials Registry Platform, and various Chinese medical databases in November 2012. We planned to include randomized or quasi-randomized controlled trials comparing needle acupuncture to a control group that used no treatment, placebo or sham treatment in neonates (less than 28 days old) with HIE. Co-interventions were allowed as long as both the intervention and the control group received the same co-interventions. We excluded trials that evaluated therapy that did not involve penetration of the skin with a needle or trials that compared different forms of acupuncture only. Two review authors independently reviewed trials for inclusion. If trials were identified, the review authors planned to assess trial quality and extract data independently. We planned to use the risk ratio (RR), risk difference (RD), and number needed to benefit (NNTB) or harm (NNTH) with 95% confidence intervals (CI) for dichotomous outcomes, and mean difference (MD) with 95% CI for continuous outcomes. No trial satisfied our predefined inclusion criteria. Existing trials only evaluated acupuncture in older infants who survived HIE. There are currently no randomized controlled trials evaluating the efficacy of acupuncture for treatment of HIE in neonates. The safety of acupuncture for HIE in neonates is unknown. The rationale for acupuncture in neonates with HIE is unclear and the evidence from randomized controlled trial is lacking. Therefore, we do not recommend acupuncture for the treatment of HIE in neonates. High quality randomized controlled trials on acupuncture for HIE in neonates are needed.-
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.mrw.interscience.wiley.com/cochrane/cochrane_clsysrev_articles_fs.html-
dc.relation.ispartofCochrane Database of Systematic Reviewsen_US
dc.rightsCochrane Database of Systematic Reviews. Copyright © John Wiley & Sons Ltd.-
dc.rightsThis review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2013, v. 1, article no. CD007968. DOI: 10.1002/14651858.CD007968.pub2. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.-
dc.subject.meshTherapy-
dc.subject.meshHumans-
dc.subject.meshHypoxia-Ischemia-
dc.subject.meshBrain-
dc.subject.meshInfant-
dc.titleAcupuncture for hypoxic ischemic encephalopathy in neonatesen_US
dc.typeArticleen_US
dc.identifier.emailWong, VCN: vcnwong@hku.hken_US
dc.identifier.emailCheuk, DKL: klcheuk@hkucc.hku.hken_US
dc.identifier.emailChu, V: vchu@hkucc.hku.hken_US
dc.identifier.authorityWong, VCN=rp00334en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/14651858.CD007968.pub2-
dc.identifier.pmid23440822-
dc.identifier.scopuseid_2-s2.0-70049107937-
dc.identifier.hkuros214774en_US
dc.identifier.hkuros176998-
dc.identifier.volume1, article no. CD007968en_US
dc.identifier.isiWOS:000314315200007-
dc.publisher.placeUnited Kingdom-
dc.identifier.f1000717985641-
dc.customcontrol.immutablecsl 130725-

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