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Article: Similarities and differences in early retinal phenotypes in hypertension and diabetes

TitleSimilarities and differences in early retinal phenotypes in hypertension and diabetes
Authors
Issue Date2011
PublisherLippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/
Citation
Journal Of Hypertension, 2011, v. 29 n. 9, p. 1667-1675 How to Cite?
AbstractThe use of retinal photography in clinical practice and research has substantially increased the knowledge about the epidemiology, natural history and significance of diabetic and hypertensive retinopathy. Early retinopathy signs, including retinal microaneurysms, blot hemorrhages, cotton-wool spots and hard exudates, are common vascular abnormalities found in middle-aged to older people with diabetes and hypertension. The presence of these early retinopathy signs is associated with an increased risk of systemic vascular diseases, such as stroke, cognitive impairment, coronary heart disease, heart failure and nephropathy. These retinopathy lesions may therefore be considered as biomarkers of systemic microvascular processes caused by diabetes and hypertension. Nevertheless, whereas the interest in retinopathy assessment continues to grow, a core concept remains undefined: what is the relative importance and contribution of diabetes and hypertension in the development of early retinopathy signs? The answer of this fundamental question holds the key to better understanding of the systemic associations of early hypertensive and diabetic retinopathy. In this review, we summarize the similarities and differences of early retinopathy signs seen in diabetes and hypertension, and discuss the conceptual relevance from epidemiological, pathophysiological, and clinical perspectives. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/183610
ISSN
2015 Impact Factor: 5.062
2015 SCImago Journal Rankings: 2.193
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorGrosso, Aen_US
dc.contributor.authorCheung, Nen_US
dc.contributor.authorVeglio, Fen_US
dc.contributor.authorWong, TYen_US
dc.date.accessioned2013-05-28T06:15:21Z-
dc.date.available2013-05-28T06:15:21Z-
dc.date.issued2011en_US
dc.identifier.citationJournal Of Hypertension, 2011, v. 29 n. 9, p. 1667-1675en_US
dc.identifier.issn0263-6352en_US
dc.identifier.urihttp://hdl.handle.net/10722/183610-
dc.description.abstractThe use of retinal photography in clinical practice and research has substantially increased the knowledge about the epidemiology, natural history and significance of diabetic and hypertensive retinopathy. Early retinopathy signs, including retinal microaneurysms, blot hemorrhages, cotton-wool spots and hard exudates, are common vascular abnormalities found in middle-aged to older people with diabetes and hypertension. The presence of these early retinopathy signs is associated with an increased risk of systemic vascular diseases, such as stroke, cognitive impairment, coronary heart disease, heart failure and nephropathy. These retinopathy lesions may therefore be considered as biomarkers of systemic microvascular processes caused by diabetes and hypertension. Nevertheless, whereas the interest in retinopathy assessment continues to grow, a core concept remains undefined: what is the relative importance and contribution of diabetes and hypertension in the development of early retinopathy signs? The answer of this fundamental question holds the key to better understanding of the systemic associations of early hypertensive and diabetic retinopathy. In this review, we summarize the similarities and differences of early retinopathy signs seen in diabetes and hypertension, and discuss the conceptual relevance from epidemiological, pathophysiological, and clinical perspectives. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/en_US
dc.relation.ispartofJournal of Hypertensionen_US
dc.subject.meshDiabetes Mellitus - Pathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertension - Pathologyen_US
dc.subject.meshPhenotypeen_US
dc.subject.meshRetina - Pathologyen_US
dc.titleSimilarities and differences in early retinal phenotypes in hypertension and diabetesen_US
dc.typeArticleen_US
dc.identifier.emailCheung, N: dannycheung@hotmail.comen_US
dc.identifier.authorityCheung, N=rp01752en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/HJH.0b013e3283496655en_US
dc.identifier.pmid21841544-
dc.identifier.scopuseid_2-s2.0-80051933364en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80051933364&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume29en_US
dc.identifier.issue9en_US
dc.identifier.spage1667en_US
dc.identifier.epage1675en_US
dc.identifier.isiWOS:000293825600001-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridGrosso, A=26534065200en_US
dc.identifier.scopusauthoridCheung, N=8054683900en_US
dc.identifier.scopusauthoridVeglio, F=7005488388en_US
dc.identifier.scopusauthoridWong, TY=7403531208en_US

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