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- Publisher Website: 10.1097/HJH.0b013e3283496655
- Scopus: eid_2-s2.0-80051933364
- PMID: 21841544
- WOS: WOS:000293825600001
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Article: Similarities and differences in early retinal phenotypes in hypertension and diabetes
Title | Similarities and differences in early retinal phenotypes in hypertension and diabetes |
---|---|
Authors | |
Keywords | diabetes hypertension microvascular complications retinal microvascular signs retinopathy |
Issue Date | 2011 |
Publisher | Lippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/ |
Citation | Journal Of Hypertension, 2011, v. 29 n. 9, p. 1667-1675 How to Cite? |
Abstract | The use of retinal photography in clinical practice and research has substantially increased the knowledge about the epidemiology, natural history and significance of diabetic and hypertensive retinopathy. Early retinopathy signs, including retinal microaneurysms, blot hemorrhages, cotton-wool spots and hard exudates, are common vascular abnormalities found in middle-aged to older people with diabetes and hypertension. The presence of these early retinopathy signs is associated with an increased risk of systemic vascular diseases, such as stroke, cognitive impairment, coronary heart disease, heart failure and nephropathy. These retinopathy lesions may therefore be considered as biomarkers of systemic microvascular processes caused by diabetes and hypertension. Nevertheless, whereas the interest in retinopathy assessment continues to grow, a core concept remains undefined: what is the relative importance and contribution of diabetes and hypertension in the development of early retinopathy signs? The answer of this fundamental question holds the key to better understanding of the systemic associations of early hypertensive and diabetic retinopathy. In this review, we summarize the similarities and differences of early retinopathy signs seen in diabetes and hypertension, and discuss the conceptual relevance from epidemiological, pathophysiological, and clinical perspectives. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins. |
Persistent Identifier | http://hdl.handle.net/10722/183610 |
ISSN | 2023 Impact Factor: 3.3 2023 SCImago Journal Rankings: 1.134 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Grosso, A | en_US |
dc.contributor.author | Cheung, N | en_US |
dc.contributor.author | Veglio, F | en_US |
dc.contributor.author | Wong, TY | en_US |
dc.date.accessioned | 2013-05-28T06:15:21Z | - |
dc.date.available | 2013-05-28T06:15:21Z | - |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | Journal Of Hypertension, 2011, v. 29 n. 9, p. 1667-1675 | en_US |
dc.identifier.issn | 0263-6352 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/183610 | - |
dc.description.abstract | The use of retinal photography in clinical practice and research has substantially increased the knowledge about the epidemiology, natural history and significance of diabetic and hypertensive retinopathy. Early retinopathy signs, including retinal microaneurysms, blot hemorrhages, cotton-wool spots and hard exudates, are common vascular abnormalities found in middle-aged to older people with diabetes and hypertension. The presence of these early retinopathy signs is associated with an increased risk of systemic vascular diseases, such as stroke, cognitive impairment, coronary heart disease, heart failure and nephropathy. These retinopathy lesions may therefore be considered as biomarkers of systemic microvascular processes caused by diabetes and hypertension. Nevertheless, whereas the interest in retinopathy assessment continues to grow, a core concept remains undefined: what is the relative importance and contribution of diabetes and hypertension in the development of early retinopathy signs? The answer of this fundamental question holds the key to better understanding of the systemic associations of early hypertensive and diabetic retinopathy. In this review, we summarize the similarities and differences of early retinopathy signs seen in diabetes and hypertension, and discuss the conceptual relevance from epidemiological, pathophysiological, and clinical perspectives. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins. | en_US |
dc.language | eng | en_US |
dc.publisher | Lippincott Williams & Wilkins, Ltd. The Journal's web site is located at http://www.jhypertension.com/ | en_US |
dc.relation.ispartof | Journal of Hypertension | en_US |
dc.subject | diabetes | - |
dc.subject | hypertension | - |
dc.subject | microvascular complications | - |
dc.subject | retinal microvascular signs | - |
dc.subject | retinopathy | - |
dc.subject.mesh | Diabetes Mellitus - Pathology | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hypertension - Pathology | en_US |
dc.subject.mesh | Phenotype | en_US |
dc.subject.mesh | Retina - Pathology | en_US |
dc.title | Similarities and differences in early retinal phenotypes in hypertension and diabetes | en_US |
dc.type | Article | en_US |
dc.identifier.email | Cheung, N: dannycheung@hotmail.com | en_US |
dc.identifier.authority | Cheung, N=rp01752 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1097/HJH.0b013e3283496655 | en_US |
dc.identifier.pmid | 21841544 | - |
dc.identifier.scopus | eid_2-s2.0-80051933364 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-80051933364&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 29 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.spage | 1667 | en_US |
dc.identifier.epage | 1675 | en_US |
dc.identifier.isi | WOS:000293825600001 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Grosso, A=26534065200 | en_US |
dc.identifier.scopusauthorid | Cheung, N=8054683900 | en_US |
dc.identifier.scopusauthorid | Veglio, F=7005488388 | en_US |
dc.identifier.scopusauthorid | Wong, TY=7403531208 | en_US |
dc.identifier.issnl | 0263-6352 | - |