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Article: Prevalence and Risk Factors of Retinal Arteriolar Emboli: The Singapore Malay Eye Study

TitlePrevalence and Risk Factors of Retinal Arteriolar Emboli: The Singapore Malay Eye Study
Authors
Issue Date2008
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ajo
Citation
American Journal Of Ophthalmology, 2008, v. 146 n. 4, p. 620-624 How to Cite?
AbstractPurpose: To examine the prevalence and risk factors of retinal arteriolar emboli, a risk predictor of stroke, in an Asian population. Design: Population-based cross-sectional study. Methods: Retinal emboli were ascertained from retinal photographs obtained from both eyes of 3,265 Asian Malays, aged 40 to 80 years, according to a standardized protocol. Risk factors were assessed from detailed standardized interviews, clinical examinations, and laboratory investigations. Results: The overall prevalence of retinal emboli was 0.6% (95% confidence interval [CI], 0.58 to 0.62). A finding of retinal emboli was strongly associated with increasing age (P = .005, for trend), but age-stratified prevalence rates were still lower than those reported from previous population-based studies of White persons. After adjusting for age and gender, the presence of retinal emboli was associated with cigarette smoking (odds ratio [OR], 5.96; 95% CI, 1.75 to 20.32), elevated total cholesterol (OR, 5.21; 95% CI, 1.93 to 12.82), low-density lipoprotein cholesterol (OR, 2.98; 95% CI, 1.20 to 7.39), and self-reported history of angina (OR, 5.67; 95% CI, 1.62 to 19.91). These associations remained significant in multivariate analysis with additional adjustment for other risk factors. Conclusions: Retinal emboli are less common in Asians than in similarly aged White persons, but are associated with similar cardiovascular risk factors. © 2008 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/183555
ISSN
2015 Impact Factor: 3.831
2015 SCImago Journal Rankings: 2.803
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, Nen_US
dc.contributor.authorLim, Len_US
dc.contributor.authorWang, JJen_US
dc.contributor.authorIslam, FMAen_US
dc.contributor.authorMitchell, Pen_US
dc.contributor.authorSaw, SMen_US
dc.contributor.authorAung, Ten_US
dc.contributor.authorWong, TYen_US
dc.date.accessioned2013-05-28T06:14:41Z-
dc.date.available2013-05-28T06:14:41Z-
dc.date.issued2008en_US
dc.identifier.citationAmerican Journal Of Ophthalmology, 2008, v. 146 n. 4, p. 620-624en_US
dc.identifier.issn0002-9394en_US
dc.identifier.urihttp://hdl.handle.net/10722/183555-
dc.description.abstractPurpose: To examine the prevalence and risk factors of retinal arteriolar emboli, a risk predictor of stroke, in an Asian population. Design: Population-based cross-sectional study. Methods: Retinal emboli were ascertained from retinal photographs obtained from both eyes of 3,265 Asian Malays, aged 40 to 80 years, according to a standardized protocol. Risk factors were assessed from detailed standardized interviews, clinical examinations, and laboratory investigations. Results: The overall prevalence of retinal emboli was 0.6% (95% confidence interval [CI], 0.58 to 0.62). A finding of retinal emboli was strongly associated with increasing age (P = .005, for trend), but age-stratified prevalence rates were still lower than those reported from previous population-based studies of White persons. After adjusting for age and gender, the presence of retinal emboli was associated with cigarette smoking (odds ratio [OR], 5.96; 95% CI, 1.75 to 20.32), elevated total cholesterol (OR, 5.21; 95% CI, 1.93 to 12.82), low-density lipoprotein cholesterol (OR, 2.98; 95% CI, 1.20 to 7.39), and self-reported history of angina (OR, 5.67; 95% CI, 1.62 to 19.91). These associations remained significant in multivariate analysis with additional adjustment for other risk factors. Conclusions: Retinal emboli are less common in Asians than in similarly aged White persons, but are associated with similar cardiovascular risk factors. © 2008 Elsevier Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ajoen_US
dc.relation.ispartofAmerican Journal of Ophthalmologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAngina Pectoris - Ethnologyen_US
dc.subject.meshArteriolesen_US
dc.subject.meshCholesterol, Ldl - Blooden_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshEmbolism - Ethnologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshHypercholesterolemia - Ethnologyen_US
dc.subject.meshMalaysia - Epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshRetinal Arteryen_US
dc.subject.meshRetinal Diseases - Ethnologyen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSingapore - Ethnologyen_US
dc.subject.meshSmoking - Ethnologyen_US
dc.subject.meshStroke - Ethnologyen_US
dc.titlePrevalence and Risk Factors of Retinal Arteriolar Emboli: The Singapore Malay Eye Studyen_US
dc.typeArticleen_US
dc.identifier.emailCheung, N: dannycheung@hotmail.comen_US
dc.identifier.authorityCheung, N=rp01752en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ajo.2008.05.033en_US
dc.identifier.pmid18639861-
dc.identifier.scopuseid_2-s2.0-51649115236en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-51649115236&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume146en_US
dc.identifier.issue4en_US
dc.identifier.spage620en_US
dc.identifier.epage624en_US
dc.identifier.isiWOS:000259742200022-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridCheung, N=8054683900en_US
dc.identifier.scopusauthoridLim, L=15053336200en_US
dc.identifier.scopusauthoridWang, JJ=55664024800en_US
dc.identifier.scopusauthoridIslam, FMA=35446440500en_US
dc.identifier.scopusauthoridMitchell, P=7402933815en_US
dc.identifier.scopusauthoridSaw, SM=7006402006en_US
dc.identifier.scopusauthoridAung, T=26643141900en_US
dc.identifier.scopusauthoridWong, TY=7403531208en_US

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