File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?

TitleIs the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?
Authors
KeywordsCoronavirus
Human Betacoronavirus 2C Emc/2012
Novel
Pneumonia
Sars
Issue Date2012
PublisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jinf
Citation
Journal Of Infection, 2012, v. 65 n. 6, p. 477-489 How to Cite?
AbstractFouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named " human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy. © 2012 The British Infection Association.
Persistent Identifierhttp://hdl.handle.net/10722/182357
ISSN
2015 Impact Factor: 4.382
2015 SCImago Journal Rankings: 2.070
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, JFWen_US
dc.contributor.authorLi, KSMen_US
dc.contributor.authorTo, KKWen_US
dc.contributor.authorCheng, VCCen_US
dc.contributor.authorChen, Hen_US
dc.contributor.authorYuen, KYen_US
dc.date.accessioned2013-04-23T08:20:03Z-
dc.date.available2013-04-23T08:20:03Z-
dc.date.issued2012en_US
dc.identifier.citationJournal Of Infection, 2012, v. 65 n. 6, p. 477-489en_US
dc.identifier.issn0163-4453en_US
dc.identifier.urihttp://hdl.handle.net/10722/182357-
dc.description.abstractFouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named " human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy. © 2012 The British Infection Association.en_US
dc.languageengen_US
dc.publisherWB Saunders Co Ltd. The Journal's web site is located at http://www.elsevier.com/locate/jinfen_US
dc.relation.ispartofJournal of Infectionen_US
dc.subjectCoronavirusen_US
dc.subjectHuman Betacoronavirus 2C Emc/2012en_US
dc.subjectNovelen_US
dc.subjectPneumoniaen_US
dc.subjectSarsen_US
dc.titleIs the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?en_US
dc.typeArticleen_US
dc.identifier.emailChan, JFW: jfwchan@hku.hken_US
dc.identifier.emailTo, KKW: kelvinto@hkucc.hku.hken_US
dc.identifier.emailYuen, KY: kyyuen@hkucc.hku.hken_US
dc.identifier.authorityChan, JFW=rp01736en_US
dc.identifier.authorityTo, KKW=rp01384en_US
dc.identifier.authorityYuen, KY=rp00366en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.jinf.2012.10.002en_US
dc.identifier.pmid23072791-
dc.identifier.scopuseid_2-s2.0-84869081784en_US
dc.identifier.hkuros224880-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84869081784&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume65en_US
dc.identifier.issue6en_US
dc.identifier.spage477en_US
dc.identifier.epage489en_US
dc.identifier.isiWOS:000311087300001-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChan, JFW=24278817900en_US
dc.identifier.scopusauthoridLi, KSM=24759122500en_US
dc.identifier.scopusauthoridTo, KKW=14323807300en_US
dc.identifier.scopusauthoridCheng, VCC=23670479400en_US
dc.identifier.scopusauthoridChen, H=55425713300en_US
dc.identifier.scopusauthoridYuen, KY=36078079100en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats