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Article: A micro PDMS flow sensor based on time-of-flight measurement for conductive liquid

TitleA micro PDMS flow sensor based on time-of-flight measurement for conductive liquid
Authors
Issue Date2013
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00542/index.htm
Citation
Microsystem Technologies, 2013, v. 19 n. 7, p. 989-994 How to Cite?
AbstractTransdermal extraction of interstitial fluid (ISF) offers an attractive method for non-invasive blood glucose monitoring. In order to calculate blood glucose concentration accurately, precise volume measurement of transdermally extracted ISF is required due to human skin's varying permeability. In this paper, we presented a novel flow sensor fabricated from polydimethylsiloxane (PDMS), designed to measure the volume of conductive liquid. The flow sensor consists of two pairs of metal electrodes, which are fabricated in the PDMS channel. The volume of liquid is measured utilizing the time-of-flight of the two electrode pairs' resistance while the liquid is flowing through the flow sensor. 1-14 μL normal saline solution was measured, the flow sensor measured volumes correlate very well (R 2 = 0.9996 and R 2 = 0.9975 for vacuum pump and syringe pump situations respectively) with the actual volumes. And the coefficient of variation for 10 times 10 μL normal saline solution measurement is 0.0077 (vacuum pump) and 0.0381 (syringe pump), respectively. The demonstrated flow sensor provides excellent functionality for conductive liquid. © 2012 Springer-Verlag Berlin Heidelberg.
Persistent Identifierhttp://hdl.handle.net/10722/182346
ISSN
2015 Impact Factor: 0.974
2015 SCImago Journal Rankings: 0.425
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYu, Hen_US
dc.contributor.authorLi, Den_US
dc.contributor.authorRoberts, RCen_US
dc.contributor.authorXu, Ken_US
dc.contributor.authorTien, NCen_US
dc.date.accessioned2013-04-23T08:19:31Z-
dc.date.available2013-04-23T08:19:31Z-
dc.date.issued2013en_US
dc.identifier.citationMicrosystem Technologies, 2013, v. 19 n. 7, p. 989-994en_US
dc.identifier.issn0946-7076en_US
dc.identifier.urihttp://hdl.handle.net/10722/182346-
dc.description.abstractTransdermal extraction of interstitial fluid (ISF) offers an attractive method for non-invasive blood glucose monitoring. In order to calculate blood glucose concentration accurately, precise volume measurement of transdermally extracted ISF is required due to human skin's varying permeability. In this paper, we presented a novel flow sensor fabricated from polydimethylsiloxane (PDMS), designed to measure the volume of conductive liquid. The flow sensor consists of two pairs of metal electrodes, which are fabricated in the PDMS channel. The volume of liquid is measured utilizing the time-of-flight of the two electrode pairs' resistance while the liquid is flowing through the flow sensor. 1-14 μL normal saline solution was measured, the flow sensor measured volumes correlate very well (R 2 = 0.9996 and R 2 = 0.9975 for vacuum pump and syringe pump situations respectively) with the actual volumes. And the coefficient of variation for 10 times 10 μL normal saline solution measurement is 0.0077 (vacuum pump) and 0.0381 (syringe pump), respectively. The demonstrated flow sensor provides excellent functionality for conductive liquid. © 2012 Springer-Verlag Berlin Heidelberg.en_US
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00542/index.htmen_US
dc.relation.ispartofMicrosystem Technologiesen_US
dc.titleA micro PDMS flow sensor based on time-of-flight measurement for conductive liquiden_US
dc.typeArticleen_US
dc.identifier.emailRoberts, RC: rcr8@hku.hken_US
dc.identifier.emailTien, NC: nctien@hku.hken_US
dc.identifier.authorityRoberts, RC=rp01738en_US
dc.identifier.authorityTien, NC=rp01604en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00542-012-1686-7en_US
dc.identifier.scopuseid_2-s2.0-84879690482en_US
dc.identifier.hkuros222876-
dc.identifier.spage989en_US
dc.identifier.epage994en_US
dc.identifier.isiWOS:000320858400004-
dc.publisher.placeGermanyen_US
dc.identifier.scopusauthoridYu, H=16240359300en_US
dc.identifier.scopusauthoridLi, D=24484642700en_US
dc.identifier.scopusauthoridRoberts, RC=24466830100en_US
dc.identifier.scopusauthoridXu, K=7403282051en_US
dc.identifier.scopusauthoridTien, NC=7006532826en_US

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