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Article: Surgical margins in breast conservation therapy: How much should we excise?

TitleSurgical margins in breast conservation therapy: How much should we excise?
Authors
KeywordsBreast conservation therapy
Local recurrence
Surgical margin
Issue Date2009
PublisherLippincott Williams & Wilkins.
Citation
Southern Medical Journal, 2009, v. 102 n. 12, p. 1234-1237 How to Cite?
AbstractBACKGROUND:: Breast conservation therapy (BCT) has become the standard of treatment for early stage breast cancer, and the surgical margin was one of the important factors that affected risk of local recurrence. This review looks at the safe margin for BCT in early stage invasive breast cancer and ductal carcinoma in situ (DCIS). METHODS:: Published literature abstracted in Medline was searched using the gateway site from the US National Library of Medicine. CONCLUSIONS:: A positive margin is associated with increased risk of local recurrence after BCT for invasive breast cancer and DCIS. However there was no cut off for the margin width and the significance of a close margin remains controversial. It was generally accepted that the risk of local recurrence was low if the margin was ≥10 mm while margins that were <2 mm were considered inadequate. The surgeon needs to balance the risk between local recurrence and cosmesis in planning BCT so that the prognosis is not compromised. Copyright © 2009 by The Southern Medical Association.
Persistent Identifierhttp://hdl.handle.net/10722/182314
ISSN
2015 Impact Factor: 0.882
2015 SCImago Journal Rankings: 0.429
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, TTen_HK
dc.contributor.authorKwong, Aen_HK
dc.date.accessioned2013-04-22T01:39:25Z-
dc.date.available2013-04-22T01:39:25Z-
dc.date.issued2009en_HK
dc.identifier.citationSouthern Medical Journal, 2009, v. 102 n. 12, p. 1234-1237en_HK
dc.identifier.issn0038-4348en_HK
dc.identifier.urihttp://hdl.handle.net/10722/182314-
dc.description.abstractBACKGROUND:: Breast conservation therapy (BCT) has become the standard of treatment for early stage breast cancer, and the surgical margin was one of the important factors that affected risk of local recurrence. This review looks at the safe margin for BCT in early stage invasive breast cancer and ductal carcinoma in situ (DCIS). METHODS:: Published literature abstracted in Medline was searched using the gateway site from the US National Library of Medicine. CONCLUSIONS:: A positive margin is associated with increased risk of local recurrence after BCT for invasive breast cancer and DCIS. However there was no cut off for the margin width and the significance of a close margin remains controversial. It was generally accepted that the risk of local recurrence was low if the margin was ≥10 mm while margins that were <2 mm were considered inadequate. The surgeon needs to balance the risk between local recurrence and cosmesis in planning BCT so that the prognosis is not compromised. Copyright © 2009 by The Southern Medical Association.en_HK
dc.languageeng-
dc.publisherLippincott Williams & Wilkins.-
dc.relation.ispartofSouthern Medical Journalen_HK
dc.rightsThis is a non-final version of an article published in final form in (provide complete journal citation)-
dc.subjectBreast conservation therapyen_HK
dc.subjectLocal recurrenceen_HK
dc.subjectSurgical marginen_HK
dc.subject.meshBreast Neoplasms - pathology - surgery-
dc.subject.meshCarcinoma, Intraductal, Noninfiltrating - pathology - surgery-
dc.subject.meshMastectomy, Segmental - methods-
dc.subject.meshNeoplasm Recurrence, Local - prevention and control-
dc.subject.meshPrognosis-
dc.titleSurgical margins in breast conservation therapy: How much should we excise?en_HK
dc.typeArticleen_HK
dc.identifier.emailKwong, A: avakwong@hkucc.hku.hken_HK
dc.identifier.authorityKwong, A=rp01734en_HK
dc.identifier.doi10.1097/SMJ.0b013e3181bfd420en_HK
dc.identifier.pmid20016431-
dc.identifier.scopuseid_2-s2.0-73949094364en_HK
dc.identifier.hkuros172701-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-73949094364&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume102en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1234en_HK
dc.identifier.epage1237en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLaw, TT=27368145000en_HK
dc.identifier.scopusauthoridKwong, A=8913654300en_HK

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