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Conference Paper: Clinical trial on effectiveness of desensitizing prophylaxis paste and toothpaste

TitleClinical trial on effectiveness of desensitizing prophylaxis paste and toothpaste
Authors
KeywordsClinical trials
Dentifrices
Dentine hypersensitivity and Health services research
Issue Date2012
PublisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925
Citation
The Annual Meeting of the International Association for Dental Research (IADR) Southeast Asian Division, Hong Kong, China, 3-4 November 2012. In Journal of Dental Research, 2012, v. 91 n. Special Issue C: abstract no. 169687 How to Cite?
AbstractObjectives: To compare the effectiveness of 8% arginine, calcium carbonate in-office desensitizing prophylaxis paste and that of 8% arginine, calcium carbonate, 1450ppm fluoride desensitizing toothpaste in reducing dentine hypersensitivity. Methods: After obtaining IRB ethical approval, subjects who had at least one tooth with sound exposed dentine on cervical buccal surface with hypersensitivity were recruited from the students and staff of The University of Hong Kong. After receiving scaling at baseline, subjects were randomly assigned to the in-office treatment or home-use toothpaste group. Clinical assessments of dentine hypersensitivity to both tactile and thermal stimuli were performed prior to the treatment at baseline and week 4 by a blinded examiner. The responses of the subjects to both stimuli were recorded using a VAS scale (0 – 10). Results: Among the 55 subjects recruited at baseline, 5 did not attend the week 4 assessment. Mean age of the remaining 50 subjects (25 in each group) was 46.2 years and 32 (64%) were female. There were no statistically significant differences regarding the background characteristics and the responses to both hypersensitivity assessments between the two groups at baseline (p>0.05). Reponses to both hypersensitivity assessments in the in-office treatment group showed no statistically significant difference between baseline and week 4 (tactile: 1.8 vs. 1.9; cold: 5.5 vs. 5.6, all p>0.05) while there was improvement in responses to both assessments in the toothpaste group between baseline and week 4 (tactile: 2.4 vs. 1.4; cold: 5.8 vs. 4.8; all p<0.05). The change in tactile hypersensitivity assessment results between the two groups was statistically significantly different (in-office: 0.1 vs. home-use: -1.0, p<0.05) but not for the thermal assessment (p>0.05). Conclusions: Daily use of the study desensitizing toothpaste is able to reduce dentine hypersensitivity up to 4 weeks but not with a single in-office application of the desensitizing prophylaxis paste.
DescriptionSession: Behavioral, Epidemiologic and Health Services Research
Persistent Identifierhttp://hdl.handle.net/10722/182056
ISSN
2015 Impact Factor: 4.602
2015 SCImago Journal Rankings: 1.714

 

DC FieldValueLanguage
dc.contributor.authorChan, CKPen_US
dc.contributor.authorLo, ECMen_US
dc.contributor.authorCorbet, EFen_US
dc.date.accessioned2013-04-17T07:20:42Z-
dc.date.available2013-04-17T07:20:42Z-
dc.date.issued2012en_US
dc.identifier.citationThe Annual Meeting of the International Association for Dental Research (IADR) Southeast Asian Division, Hong Kong, China, 3-4 November 2012. In Journal of Dental Research, 2012, v. 91 n. Special Issue C: abstract no. 169687en_US
dc.identifier.issn0022-0345-
dc.identifier.urihttp://hdl.handle.net/10722/182056-
dc.descriptionSession: Behavioral, Epidemiologic and Health Services Research-
dc.description.abstractObjectives: To compare the effectiveness of 8% arginine, calcium carbonate in-office desensitizing prophylaxis paste and that of 8% arginine, calcium carbonate, 1450ppm fluoride desensitizing toothpaste in reducing dentine hypersensitivity. Methods: After obtaining IRB ethical approval, subjects who had at least one tooth with sound exposed dentine on cervical buccal surface with hypersensitivity were recruited from the students and staff of The University of Hong Kong. After receiving scaling at baseline, subjects were randomly assigned to the in-office treatment or home-use toothpaste group. Clinical assessments of dentine hypersensitivity to both tactile and thermal stimuli were performed prior to the treatment at baseline and week 4 by a blinded examiner. The responses of the subjects to both stimuli were recorded using a VAS scale (0 – 10). Results: Among the 55 subjects recruited at baseline, 5 did not attend the week 4 assessment. Mean age of the remaining 50 subjects (25 in each group) was 46.2 years and 32 (64%) were female. There were no statistically significant differences regarding the background characteristics and the responses to both hypersensitivity assessments between the two groups at baseline (p>0.05). Reponses to both hypersensitivity assessments in the in-office treatment group showed no statistically significant difference between baseline and week 4 (tactile: 1.8 vs. 1.9; cold: 5.5 vs. 5.6, all p>0.05) while there was improvement in responses to both assessments in the toothpaste group between baseline and week 4 (tactile: 2.4 vs. 1.4; cold: 5.8 vs. 4.8; all p<0.05). The change in tactile hypersensitivity assessment results between the two groups was statistically significantly different (in-office: 0.1 vs. home-use: -1.0, p<0.05) but not for the thermal assessment (p>0.05). Conclusions: Daily use of the study desensitizing toothpaste is able to reduce dentine hypersensitivity up to 4 weeks but not with a single in-office application of the desensitizing prophylaxis paste.-
dc.languageengen_US
dc.publisherSage Publications, Inc.. The Journal's web site is located at http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201925-
dc.relation.ispartofJournal of Dental Researchen_US
dc.rightsJournal of Dental Research. Copyright © Sage Publications, Inc..-
dc.subjectClinical trials-
dc.subjectDentifrices-
dc.subjectDentine hypersensitivity and Health services research-
dc.titleClinical trial on effectiveness of desensitizing prophylaxis paste and toothpasteen_US
dc.typeConference_Paperen_US
dc.identifier.emailChan, CKP: ckpchan@hku.hken_US
dc.identifier.emailLo, ECM: hrdplcm@hkucc.hku.hken_US
dc.identifier.emailCorbet, EF: efcorbet@hku.hken_US
dc.identifier.authorityChan, CKP=rp00011en_US
dc.identifier.authorityLo, ECM=rp00015en_US
dc.identifier.authorityCorbet, EF=rp00005en_US
dc.identifier.hkuros213904en_US
dc.identifier.volume91en_US
dc.identifier.issueSpecial Issue C: abstract no. 169687en_US
dc.publisher.placeUnited States-

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