File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Ultrasound screening of fetal structural abnormalities at 12 to 14 weeks in Hong Kong

TitleUltrasound screening of fetal structural abnormalities at 12 to 14 weeks in Hong Kong
Authors
Issue Date2004
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
Citation
Prenatal Diagnosis, 2004, v. 24 n. 2, p. 92-97 How to Cite?
AbstractObjective: Ultrasound screening for fetal abnormalities is conventionally performed at 18 to 20 weeks of gestation. Recent data suggested that many fetal structural abnormalities could be detected by ultrasound examination at 12 to 14 weeks of pregnancy. In this study, we investigated the effectiveness of early ultrasound examination in the detection of fetal abnormalities in women aged 35 years or older. Methods: From February 1998 to March 2001, pregnant women aged 35 or above were examined by transabdominal and transvaginal sonography between 12 and 14 weeks of gestation. If the anatomical survey was normal, the women underwent routine 16- to 20-week ultrasound examination. Pregnancy outcome was obtained from the hospital records or by contacting the subjects. Results: Twenty-six of the 1609 fetuses had structural abnormalities. Fourteen were detected at the ultrasound examination at 12 to 14 weeks. Detection rate was 53.8% (14/26; 95% CI 44, 64) with a false-positive rate of 0.3% (5/1583; 95% CI 0.16, 0.44). Six additional abnormalities (23.1%, 6/26) were detected at 16- to 20-week ultrasound examination. The overall detection rate of structural abnormalities was 76.9% (20/26; 95% CI 68.6, 85.2). Conclusions: The effectiveness of ultrasound examination at 12 to 14 weeks to screen for fetal abnormalities approached that achieved at 20 weeks and can be a good adjunct to the conventional examination. Copyright © 2004 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/180673
ISSN
2015 Impact Factor: 3.043
2015 SCImago Journal Rankings: 1.450
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, Men_US
dc.contributor.authorLam, YHen_US
dc.contributor.authorLee, CPen_US
dc.contributor.authorTang, MHYen_US
dc.date.accessioned2013-01-28T01:41:01Z-
dc.date.available2013-01-28T01:41:01Z-
dc.date.issued2004en_US
dc.identifier.citationPrenatal Diagnosis, 2004, v. 24 n. 2, p. 92-97en_US
dc.identifier.issn0197-3851en_US
dc.identifier.urihttp://hdl.handle.net/10722/180673-
dc.description.abstractObjective: Ultrasound screening for fetal abnormalities is conventionally performed at 18 to 20 weeks of gestation. Recent data suggested that many fetal structural abnormalities could be detected by ultrasound examination at 12 to 14 weeks of pregnancy. In this study, we investigated the effectiveness of early ultrasound examination in the detection of fetal abnormalities in women aged 35 years or older. Methods: From February 1998 to March 2001, pregnant women aged 35 or above were examined by transabdominal and transvaginal sonography between 12 and 14 weeks of gestation. If the anatomical survey was normal, the women underwent routine 16- to 20-week ultrasound examination. Pregnancy outcome was obtained from the hospital records or by contacting the subjects. Results: Twenty-six of the 1609 fetuses had structural abnormalities. Fourteen were detected at the ultrasound examination at 12 to 14 weeks. Detection rate was 53.8% (14/26; 95% CI 44, 64) with a false-positive rate of 0.3% (5/1583; 95% CI 0.16, 0.44). Six additional abnormalities (23.1%, 6/26) were detected at 16- to 20-week ultrasound examination. The overall detection rate of structural abnormalities was 76.9% (20/26; 95% CI 68.6, 85.2). Conclusions: The effectiveness of ultrasound examination at 12 to 14 weeks to screen for fetal abnormalities approached that achieved at 20 weeks and can be a good adjunct to the conventional examination. Copyright © 2004 John Wiley & Sons, Ltd.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252en_US
dc.relation.ispartofPrenatal Diagnosisen_US
dc.subject.meshAdulten_US
dc.subject.meshCongenital Abnormalities - Diagnosis - Embryology - Ultrasonographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFetus - Abnormalitiesen_US
dc.subject.meshHong Kongen_US
dc.subject.meshHumansen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Outcomeen_US
dc.subject.meshPregnancy Trimester, Firsten_US
dc.subject.meshPrenatal Diagnosis - Methodsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshUltrasonography, Prenatal - Methodsen_US
dc.titleUltrasound screening of fetal structural abnormalities at 12 to 14 weeks in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailTang, MHY: mhytang@hkucc.hku.hken_US
dc.identifier.authorityTang, MHY=rp01701en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/pd.798en_US
dc.identifier.pmid14974113-
dc.identifier.scopuseid_2-s2.0-1542351212en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1542351212&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue2en_US
dc.identifier.spage92en_US
dc.identifier.epage97en_US
dc.identifier.isiWOS:000189184600004-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridChen, M=26028797000en_US
dc.identifier.scopusauthoridLam, YH=7202563903en_US
dc.identifier.scopusauthoridLee, CP=7410149538en_US
dc.identifier.scopusauthoridTang, MHY=8943401300en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats