File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Evaluation of the prognostic value of 2005 St Gallen risk categories for operated breast cancers in Hong Kong

TitleEvaluation of the prognostic value of 2005 St Gallen risk categories for operated breast cancers in Hong Kong
Authors
Issue Date2008
PublisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/breast
Citation
Breast, 2008, v. 29 n. 1, p. 58-63 How to Cite?
AbstractIncorporating various new and conventional risk factors, the 2005 St Gallen risk categorization is a potentially useful prognostic tool for breast cancers. We conducted a retrospective study to evaluate its application in Hong Kong. Of the 902 included female breast cancers with median follow-up of 5.4 years, 7%, 63% and 30% patients were classified as low-, intermediate- and high-risk categories, respectively. Their corresponding 5-year distant disease-free survivals (DDFS) were 100%, 92% and 72%, respectively (p<0.00005). In the intermediate-risk category, node-positive patients had marginally inferior 5-year DDFS than node-negative patients (89% vs. 93%, p=0.0551). In the high-risk category, patients having HER2 overexpressed tumors and 1-3 positive nodes had significantly better DDFS than other patients with ≥4 positive nodes (89% vs. 65%, p=0.0001). Overall, the 2005 St Gallen risk categorization had high prognostic value. However, the impact of HER2 overexpression might be affected by reproducibility of HER2 tests. © 2007 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/180446
ISSN
2015 Impact Factor: 2.74
2015 SCImago Journal Rankings: 1.346
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYau, TKen_US
dc.contributor.authorSoong, ISen_US
dc.contributor.authorChan, Ken_US
dc.contributor.authorChang, Aen_US
dc.contributor.authorSze, Hen_US
dc.contributor.authorYeung, MWen_US
dc.contributor.authorTung, Ren_US
dc.contributor.authorLau, Sen_US
dc.contributor.authorLee, Aen_US
dc.date.accessioned2013-01-28T01:38:11Z-
dc.date.available2013-01-28T01:38:11Z-
dc.date.issued2008en_US
dc.identifier.citationBreast, 2008, v. 29 n. 1, p. 58-63en_US
dc.identifier.issn0960-9776en_US
dc.identifier.urihttp://hdl.handle.net/10722/180446-
dc.description.abstractIncorporating various new and conventional risk factors, the 2005 St Gallen risk categorization is a potentially useful prognostic tool for breast cancers. We conducted a retrospective study to evaluate its application in Hong Kong. Of the 902 included female breast cancers with median follow-up of 5.4 years, 7%, 63% and 30% patients were classified as low-, intermediate- and high-risk categories, respectively. Their corresponding 5-year distant disease-free survivals (DDFS) were 100%, 92% and 72%, respectively (p<0.00005). In the intermediate-risk category, node-positive patients had marginally inferior 5-year DDFS than node-negative patients (89% vs. 93%, p=0.0551). In the high-risk category, patients having HER2 overexpressed tumors and 1-3 positive nodes had significantly better DDFS than other patients with ≥4 positive nodes (89% vs. 65%, p=0.0001). Overall, the 2005 St Gallen risk categorization had high prognostic value. However, the impact of HER2 overexpression might be affected by reproducibility of HER2 tests. © 2007 Elsevier Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/breasten_US
dc.relation.ispartofBreasten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshBreast Neoplasms - Epidemiology - Genetics - Pathology - Surgeryen_US
dc.subject.meshCarcinoma - Epidemiology - Genetics - Pathology - Secondary - Surgeryen_US
dc.subject.meshDisease-Free Survivalen_US
dc.subject.meshFemaleen_US
dc.subject.meshGene Expression Profilingen_US
dc.subject.meshGenes, Erbb-2en_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphatic Metastasisen_US
dc.subject.meshMastectomy - Statistics & Numerical Dataen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Staging - Methodsen_US
dc.subject.meshPrognosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleEvaluation of the prognostic value of 2005 St Gallen risk categories for operated breast cancers in Hong Kongen_US
dc.typeArticleen_US
dc.identifier.emailSze, H: henrysze@graduate.hku.hken_US
dc.identifier.authoritySze, H=rp01697en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.breast.2007.06.007en_US
dc.identifier.pmid17804235en_US
dc.identifier.scopuseid_2-s2.0-38949129190en_US
dc.identifier.hkuros266137-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38949129190&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume29en_US
dc.identifier.issue1en_US
dc.identifier.spage58en_US
dc.identifier.epage63en_US
dc.identifier.isiWOS:000257274300013-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridYau, TK=7006540678en_US
dc.identifier.scopusauthoridSoong, IS=9239786900en_US
dc.identifier.scopusauthoridChan, K=7406034305en_US
dc.identifier.scopusauthoridChang, A=27168648000en_US
dc.identifier.scopusauthoridSze, H=23490726900en_US
dc.identifier.scopusauthoridYeung, MW=7101861680en_US
dc.identifier.scopusauthoridTung, R=36148603300en_US
dc.identifier.scopusauthoridLau, S=7401596190en_US
dc.identifier.scopusauthoridLee, A=17035384900en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats