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Conference Paper: Packaging of disposable chips for bioanalytical applications

TitlePackaging of disposable chips for bioanalytical applications
Authors
Issue Date2004
Citation
Proceedings - Electronic Components And Technology Conference, 2004, v. 1, p. 853-861 How to Cite?
AbstractThe need for point-of-care or point-of-use diagnostic sensors in the health care industry as well as for food and water pathogen testing has been a major factor in the development of low-cost microfluidic devices. Polymer materials have been the obvious choice due to their cost effectiveness. Whereas, due to significant advances in MEMS manufacturing and microelectronic packaging, a significant body of knowledge is available for manufacturing and packaging semiconductor-based or glass-based bioanalytical microdevices, packaging know-how for polymer-based microfluidic devices is not as readily available. In this paper, the realization of microfluidic packages by bonding several stacked layers of microstructured polymer films in a reel-to-reel manufacturing system is shown to be promising approach. The smart division between disposable and reusable system parts as well as the careful selection of materials, based on microstructuring, bonding, biocompatibility and autofluorescence criteria may lead to bioanalytical devices with a very competitive cost of ownership per test. For the realization of such microfluidic disposables, microstructuring technologies based on UV laser micromachining, bonding technologies based on thermal diffusion, adhesives and microwave sealing using conductive polymers, and surface modification approaches for the reduction of non-specific protein binding are discussed.
Persistent Identifierhttp://hdl.handle.net/10722/179585
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorSchuenemann, Men_US
dc.contributor.authorThomson, Den_US
dc.contributor.authorAtkins, Men_US
dc.contributor.authorGarst, Sen_US
dc.contributor.authorYussuf, Aen_US
dc.contributor.authorSolomon, Men_US
dc.contributor.authorHayes, Jen_US
dc.contributor.authorHarvey, Een_US
dc.date.accessioned2012-12-19T10:00:01Z-
dc.date.available2012-12-19T10:00:01Z-
dc.date.issued2004en_US
dc.identifier.citationProceedings - Electronic Components And Technology Conference, 2004, v. 1, p. 853-861en_US
dc.identifier.issn0569-5503en_US
dc.identifier.urihttp://hdl.handle.net/10722/179585-
dc.description.abstractThe need for point-of-care or point-of-use diagnostic sensors in the health care industry as well as for food and water pathogen testing has been a major factor in the development of low-cost microfluidic devices. Polymer materials have been the obvious choice due to their cost effectiveness. Whereas, due to significant advances in MEMS manufacturing and microelectronic packaging, a significant body of knowledge is available for manufacturing and packaging semiconductor-based or glass-based bioanalytical microdevices, packaging know-how for polymer-based microfluidic devices is not as readily available. In this paper, the realization of microfluidic packages by bonding several stacked layers of microstructured polymer films in a reel-to-reel manufacturing system is shown to be promising approach. The smart division between disposable and reusable system parts as well as the careful selection of materials, based on microstructuring, bonding, biocompatibility and autofluorescence criteria may lead to bioanalytical devices with a very competitive cost of ownership per test. For the realization of such microfluidic disposables, microstructuring technologies based on UV laser micromachining, bonding technologies based on thermal diffusion, adhesives and microwave sealing using conductive polymers, and surface modification approaches for the reduction of non-specific protein binding are discussed.en_US
dc.languageengen_US
dc.relation.ispartofProceedings - Electronic Components and Technology Conferenceen_US
dc.titlePackaging of disposable chips for bioanalytical applicationsen_US
dc.typeConference_Paperen_US
dc.identifier.emailThomson, D: dthomson@hku.hken_US
dc.identifier.authorityThomson, D=rp00788en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-10444221690en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-10444221690&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume1en_US
dc.identifier.spage853en_US
dc.identifier.epage861en_US
dc.identifier.scopusauthoridSchuenemann, M=6603166430en_US
dc.identifier.scopusauthoridThomson, D=7202586830en_US
dc.identifier.scopusauthoridAtkins, M=7102310581en_US
dc.identifier.scopusauthoridGarst, S=6505589441en_US
dc.identifier.scopusauthoridYussuf, A=8687181100en_US
dc.identifier.scopusauthoridSolomon, M=7202021789en_US
dc.identifier.scopusauthoridHayes, J=7403555100en_US
dc.identifier.scopusauthoridHarvey, E=7103155726en_US

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