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Article: Effects of Buyanghuanwu decoction on nerve proliferation in rats with sequelae of ischemic stroke

TitleEffects of Buyanghuanwu decoction on nerve proliferation in rats with sequelae of ischemic stroke
Authors
Issue Date2006
Citation
Nan Fang Yi Ke Da Xue Xue Bao = Journal Of Southern Medical University, 2006, v. 26 n. 2, p. 189-192 How to Cite?
AbstractOBJECTIVE: To examine the effect of Buyanghuanwu decoction (BYHWD) in inducing nerve proliferation in rats with sequelae of ischemic stroke. METHODS: A rat model of ischemic stroke sequelae was established by means of craniectomy in which the right common carotid artery was ligated with 4-0 silk thread followed by cauterization of the right middle cerebral artery. Programmed electric shock was administered 24 h after the onset of ischemic stroke for 2 h daily for 20 consecutive days. The rats in sham operation group were not subjected to ligation of the right common carotid artery or right middle cerebral artery occlusion. The rats in the treatment groups were given oral BYHWD for 15 consecutive days. All the rats received repeated intraperitoneal injections of the cell proliferation-specific marker 5-bromodeoxyuridine (BrdU), and the intake of BrdU in the cerebral tissues was determined by immunohistochemistry. RESULTS: The number of BrdU-immunoreactive cells in the cerebral tissues of BYHWD-treated rats was significantly greater than that in the untreated model group. CONCLUSION: BYHWD can promote nerve proliferation in rats with ischemic stroke sequelae.
Persistent Identifierhttp://hdl.handle.net/10722/179445
ISSN
2015 SCImago Journal Rankings: 0.170

 

DC FieldValueLanguage
dc.contributor.authorTan, XHen_US
dc.contributor.authorQu, HDen_US
dc.contributor.authorPeng, Ken_US
dc.contributor.authorChen, YYen_US
dc.contributor.authorTong, Len_US
dc.contributor.authorShen, JGen_US
dc.contributor.authorZhu, CWen_US
dc.date.accessioned2012-12-19T09:56:38Z-
dc.date.available2012-12-19T09:56:38Z-
dc.date.issued2006en_US
dc.identifier.citationNan Fang Yi Ke Da Xue Xue Bao = Journal Of Southern Medical University, 2006, v. 26 n. 2, p. 189-192en_US
dc.identifier.issn1673-4254en_US
dc.identifier.urihttp://hdl.handle.net/10722/179445-
dc.description.abstractOBJECTIVE: To examine the effect of Buyanghuanwu decoction (BYHWD) in inducing nerve proliferation in rats with sequelae of ischemic stroke. METHODS: A rat model of ischemic stroke sequelae was established by means of craniectomy in which the right common carotid artery was ligated with 4-0 silk thread followed by cauterization of the right middle cerebral artery. Programmed electric shock was administered 24 h after the onset of ischemic stroke for 2 h daily for 20 consecutive days. The rats in sham operation group were not subjected to ligation of the right common carotid artery or right middle cerebral artery occlusion. The rats in the treatment groups were given oral BYHWD for 15 consecutive days. All the rats received repeated intraperitoneal injections of the cell proliferation-specific marker 5-bromodeoxyuridine (BrdU), and the intake of BrdU in the cerebral tissues was determined by immunohistochemistry. RESULTS: The number of BrdU-immunoreactive cells in the cerebral tissues of BYHWD-treated rats was significantly greater than that in the untreated model group. CONCLUSION: BYHWD can promote nerve proliferation in rats with ischemic stroke sequelae.en_US
dc.languageengen_US
dc.relation.ispartofNan fang yi ke da xue xue bao = Journal of Southern Medical Universityen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBromodeoxyuridine - Metabolism - Pharmacokineticsen_US
dc.subject.meshCell Proliferation - Drug Effectsen_US
dc.subject.meshDrugs, Chinese Herbal - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHippocampus - Drug Effects - Metabolism - Pathologyen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshInfarction, Middle Cerebral Artery - Drug Therapy - Physiopathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshNeurons - Drug Effects - Metabolism - Pathologyen_US
dc.subject.meshNeuroprotective Agents - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshRandom Allocationen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.titleEffects of Buyanghuanwu decoction on nerve proliferation in rats with sequelae of ischemic strokeen_US
dc.typeArticleen_US
dc.identifier.emailShen, JG: shenjg@hku.hken_US
dc.identifier.authorityShen, JG=rp00487en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid16503526-
dc.identifier.scopuseid_2-s2.0-41949109033en_US
dc.identifier.volume26en_US
dc.identifier.issue2en_US
dc.identifier.spage189en_US
dc.identifier.epage192en_US
dc.identifier.scopusauthoridTan, XH=24068123000en_US
dc.identifier.scopusauthoridQu, HD=7101947180en_US
dc.identifier.scopusauthoridPeng, K=7102562985en_US
dc.identifier.scopusauthoridChen, YY=7601427941en_US
dc.identifier.scopusauthoridTong, L=7201891650en_US
dc.identifier.scopusauthoridShen, JG=7404929947en_US
dc.identifier.scopusauthoridZhu, CW=7403440102en_US

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