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Article: The effect of four kinds of traditional Chinese herbal compound on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axis

TitleThe effect of four kinds of traditional Chinese herbal compound on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axis
4種中藥複方對大鼠實驗性急性應激行為及下丘腦-垂體-腎上腺軸的影響
Authors
Issue Date2005
PublisherZhongguo Zhongyao Zazhishe. The Journal's web site is located at http://www.cjcmm.com.cn/cjcmm/ch/index.aspx
Citation
Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 2005, v. 30 n. 23, p. 1863-1866 How to Cite?
中國中葯雜誌, 2005, v. 30 n. 23, p. 1863-1866 How to Cite?
AbstractObjective: To study the effects of four kinds of traditional Chinese herbal compound, Sini powder, Banxiahoupu soup, Ganmaidazao soup and Guizhigancaolonggumuli soup, on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axis. Method: Rats were divide into 7 groups: normal group, model 1 and 2 groups, Sini powder group, Banxiahoupu soup group, Ganmaidazao soup group, and Guizhigancaolonggumuli soup group. The behaviors of the rats and their CRH of the hypothalamus, ACTH of plasma and CORT of serum (by the means of radio-immunity) were detected. Result: Sini powder could reduce the crossing times of open-field test (P < 0.01) and the contents of CRH and CORT (P < 0.01, P < 0.05); Banxiahoupu soup could extent the still time of tail-hanging test (P < 0.05) and the content of CRH (P < 0.05); Ganmaidazao soup could prolong the still time (P < 0.05) and reduce the struggle times (P < 0.01) of tail-hanging test and reduce the contents of CRH, ACTH and CORT (P < 0.01, P < 0.05); Guizhigancaolonggumuli soup could reduce the crossing times of open-field test (P < 0.01), extent the still time (P < 0.05) and reduce the struggle times (P < 0.01) of tail-hanging test of tail-hanging test, also reduce the contents of CRH, ACTH and CORT (P < 0.01, P < 0.05). Conclusion: The four kinds of traditional Chinese herbal compound can increase the ability of anti stress by affect the different taches of the hypothalamus-pituitary-adrenal gland axle and change the stress behaviors, which are based on their respective functions of regulating Qi, dispersing phlegm, tonifying Qi and warming Yang.
Persistent Identifierhttp://hdl.handle.net/10722/179437
ISSN
2015 SCImago Journal Rankings: 0.164
References

 

DC FieldValueLanguage
dc.contributor.authorTong, Yen_US
dc.contributor.authorZou, Jen_US
dc.contributor.authorNi, LQen_US
dc.contributor.authorLiang, SHen_US
dc.contributor.authorCao, BYen_US
dc.contributor.authorChen, HJen_US
dc.date.accessioned2012-12-19T09:56:34Z-
dc.date.available2012-12-19T09:56:34Z-
dc.date.issued2005en_US
dc.identifier.citationZhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 2005, v. 30 n. 23, p. 1863-1866en_US
dc.identifier.citation中國中葯雜誌, 2005, v. 30 n. 23, p. 1863-1866-
dc.identifier.issn1001-5302en_US
dc.identifier.urihttp://hdl.handle.net/10722/179437-
dc.description.abstractObjective: To study the effects of four kinds of traditional Chinese herbal compound, Sini powder, Banxiahoupu soup, Ganmaidazao soup and Guizhigancaolonggumuli soup, on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axis. Method: Rats were divide into 7 groups: normal group, model 1 and 2 groups, Sini powder group, Banxiahoupu soup group, Ganmaidazao soup group, and Guizhigancaolonggumuli soup group. The behaviors of the rats and their CRH of the hypothalamus, ACTH of plasma and CORT of serum (by the means of radio-immunity) were detected. Result: Sini powder could reduce the crossing times of open-field test (P < 0.01) and the contents of CRH and CORT (P < 0.01, P < 0.05); Banxiahoupu soup could extent the still time of tail-hanging test (P < 0.05) and the content of CRH (P < 0.05); Ganmaidazao soup could prolong the still time (P < 0.05) and reduce the struggle times (P < 0.01) of tail-hanging test and reduce the contents of CRH, ACTH and CORT (P < 0.01, P < 0.05); Guizhigancaolonggumuli soup could reduce the crossing times of open-field test (P < 0.01), extent the still time (P < 0.05) and reduce the struggle times (P < 0.01) of tail-hanging test of tail-hanging test, also reduce the contents of CRH, ACTH and CORT (P < 0.01, P < 0.05). Conclusion: The four kinds of traditional Chinese herbal compound can increase the ability of anti stress by affect the different taches of the hypothalamus-pituitary-adrenal gland axle and change the stress behaviors, which are based on their respective functions of regulating Qi, dispersing phlegm, tonifying Qi and warming Yang.en_US
dc.languageengen_US
dc.publisherZhongguo Zhongyao Zazhishe. The Journal's web site is located at http://www.cjcmm.com.cn/cjcmm/ch/index.aspxen_US
dc.relation.ispartofZhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medicaen_US
dc.relation.ispartof中國中葯雜誌-
dc.subject.meshAdrenocorticotropic Hormone - Blooden_US
dc.subject.meshAnimalsen_US
dc.subject.meshBehavior, Animal - Drug Effectsen_US
dc.subject.meshCorticosterone - Blooden_US
dc.subject.meshCorticotropin-Releasing Hormone - Metabolismen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshDrugs, Chinese Herbal - Isolation & Purification - Pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHypothalamo-Hypophyseal System - Drug Effectsen_US
dc.subject.meshHypothalamus - Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMateria Medica - Isolation & Purification - Pharmacologyen_US
dc.subject.meshMedicine, Chinese Traditionalen_US
dc.subject.meshOstreidae - Chemistryen_US
dc.subject.meshPlants, Medicinalen_US
dc.subject.meshRandom Allocationen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Sprague-Dawleyen_US
dc.subject.meshStress, Physiological - Physiopathologyen_US
dc.titleThe effect of four kinds of traditional Chinese herbal compound on the experimental acute stress behaviors and the hypothalamus-pituitary-adrenal gland axisen_US
dc.title4種中藥複方對大鼠實驗性急性應激行為及下丘腦-垂體-腎上腺軸的影響-
dc.typeArticleen_US
dc.identifier.emailTong, Y: tongyao@hku.hken_US
dc.identifier.authorityTong, Y=rp00509en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.3321/j.issn:1001-5302.2005.23.018-
dc.identifier.pmid16499029-
dc.identifier.scopuseid_2-s2.0-33751261382en_US
dc.identifier.hkuros104672-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33751261382&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume30en_US
dc.identifier.issue23en_US
dc.identifier.spage1863en_US
dc.identifier.epage1866en_US
dc.publisher.placeChinaen_US
dc.identifier.scopusauthoridTong, Y=9045384000en_US
dc.identifier.scopusauthoridZou, J=55222615400en_US
dc.identifier.scopusauthoridNi, LQ=9036497400en_US
dc.identifier.scopusauthoridLiang, SH=7402146678en_US
dc.identifier.scopusauthoridCao, BY=14051682900en_US
dc.identifier.scopusauthoridChen, HJ=38163238900en_US

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