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Article: Therapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders

TitleTherapeutic effects of herbal extracts and constituents in animal models of psychiatric disorders
Authors
Issue Date2004
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
Citation
Life Sciences, 2004, v. 75 n. 14, p. 1659-1699 How to Cite?
AbstractA search for novel pharmacotherapy from medicinal plants for psychiatric illnesses has progressed significantly in the past decade. This is reflected in the large number of herbal preparations for which psychotherapeutic potential has been evaluated in a variety of animal models. The objective of this review is to provide an overview of herbal extracts and constituents that have significant therapeutic effects in animal models of psychiatric illnesses. Eighty five individual herbs reviewed were classified as anxiolytic, antidepressant, neuroleptic, antidementia, or anti-substance abuse herbs. The full scientific name of each herb, herbal part used, active constituent, extract, dose range and route, animal model, possible mechanisms of action, and pertinent references are presented via synoptic tables. The herbal mixtures were also mentioned. A considerable number of herbal constituents whose behavioral effects and pharmacological actions have been well characterized may be good candidates for further investigations that may ultimately result in clinical use. The investigation of a large portion of the herbal extracts and herbal mixtures is in its infancy. Herbal remedies that have demonstrable psychotherapeutic activities have provided a potential to psychiatric pharmaceuticals and deserve increased attention in future studies. © 2004 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/179430
ISSN
2015 Impact Factor: 2.685
2015 SCImago Journal Rankings: 1.056
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhang, ZJen_US
dc.date.accessioned2012-12-19T09:56:26Z-
dc.date.available2012-12-19T09:56:26Z-
dc.date.issued2004en_US
dc.identifier.citationLife Sciences, 2004, v. 75 n. 14, p. 1659-1699en_US
dc.identifier.issn0024-3205en_US
dc.identifier.urihttp://hdl.handle.net/10722/179430-
dc.description.abstractA search for novel pharmacotherapy from medicinal plants for psychiatric illnesses has progressed significantly in the past decade. This is reflected in the large number of herbal preparations for which psychotherapeutic potential has been evaluated in a variety of animal models. The objective of this review is to provide an overview of herbal extracts and constituents that have significant therapeutic effects in animal models of psychiatric illnesses. Eighty five individual herbs reviewed were classified as anxiolytic, antidepressant, neuroleptic, antidementia, or anti-substance abuse herbs. The full scientific name of each herb, herbal part used, active constituent, extract, dose range and route, animal model, possible mechanisms of action, and pertinent references are presented via synoptic tables. The herbal mixtures were also mentioned. A considerable number of herbal constituents whose behavioral effects and pharmacological actions have been well characterized may be good candidates for further investigations that may ultimately result in clinical use. The investigation of a large portion of the herbal extracts and herbal mixtures is in its infancy. Herbal remedies that have demonstrable psychotherapeutic activities have provided a potential to psychiatric pharmaceuticals and deserve increased attention in future studies. © 2004 Elsevier Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescieen_US
dc.relation.ispartofLife Sciencesen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-Anxiety Agents - Therapeutic Useen_US
dc.subject.meshAntidepressive Agents - Therapeutic Useen_US
dc.subject.meshAntipsychotic Agents - Therapeutic Useen_US
dc.subject.meshDementia - Drug Therapyen_US
dc.subject.meshDisease Models, Animalen_US
dc.subject.meshMental Disorders - Drug Therapyen_US
dc.subject.meshPhytotherapyen_US
dc.subject.meshPlant Extracts - Therapeutic Useen_US
dc.subject.meshPlants, Medicinal - Chemistryen_US
dc.subject.meshPubmeden_US
dc.subject.meshSubstance-Related Disorders - Drug Therapyen_US
dc.titleTherapeutic effects of herbal extracts and constituents in animal models of psychiatric disordersen_US
dc.typeArticleen_US
dc.identifier.emailZhang, ZJ: zhangzj@hkucc.hku.hken_US
dc.identifier.authorityZhang, ZJ=rp01297en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.lfs.2004.04.014en_US
dc.identifier.pmid15268969-
dc.identifier.scopuseid_2-s2.0-3242741013en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-3242741013&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume75en_US
dc.identifier.issue14en_US
dc.identifier.spage1659en_US
dc.identifier.epage1699en_US
dc.identifier.isiWOS:000223012100001-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridZhang, ZJ=8061473900en_US

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