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Article: Acetophenone glycosides from thyme (Thymus vulgaris L.)

TitleAcetophenone glycosides from thyme (Thymus vulgaris L.)
Authors
Issue Date1999
PublisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/jafcau
Citation
Journal Of Agricultural And Food Chemistry, 1999, v. 47 n. 5, p. 1911-1914 How to Cite?
AbstractFour acetophenone glycosides were isolated from the butanol-soluble fraction of thyme extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR). Among them, two new compounds, 4- hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-β-D- apiofuranosyl]-(1-2)-β-D-glucopyranoside (1) and 4-hydroxyacetophenone 4-O- [5-O-(4-hydroxybenzoyl)β-D-apiofuranosyl]-(1-2)-β-D-glucopyranoside (2), were determined. Compound 1 showed weak cytotoxicity, inhibiting DNA synthesis of human leukemia cells.
Persistent Identifierhttp://hdl.handle.net/10722/178652
ISSN
2015 Impact Factor: 2.857
2015 SCImago Journal Rankings: 1.246
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWang, Men_US
dc.contributor.authorKikuzaki, Hen_US
dc.contributor.authorLin, CCen_US
dc.contributor.authorKahyaoglu, Aen_US
dc.contributor.authorHuang, MTen_US
dc.contributor.authorNakatani, Nen_US
dc.contributor.authorHo, CTen_US
dc.date.accessioned2012-12-19T09:48:57Z-
dc.date.available2012-12-19T09:48:57Z-
dc.date.issued1999en_US
dc.identifier.citationJournal Of Agricultural And Food Chemistry, 1999, v. 47 n. 5, p. 1911-1914en_US
dc.identifier.issn0021-8561en_US
dc.identifier.urihttp://hdl.handle.net/10722/178652-
dc.description.abstractFour acetophenone glycosides were isolated from the butanol-soluble fraction of thyme extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR). Among them, two new compounds, 4- hydroxyacetophenone 4-O-[5-O-(3,5-dimethoxy-4-hydroxybenzoyl)-β-D- apiofuranosyl]-(1-2)-β-D-glucopyranoside (1) and 4-hydroxyacetophenone 4-O- [5-O-(4-hydroxybenzoyl)β-D-apiofuranosyl]-(1-2)-β-D-glucopyranoside (2), were determined. Compound 1 showed weak cytotoxicity, inhibiting DNA synthesis of human leukemia cells.en_US
dc.languageengen_US
dc.publisherAmerican Chemical Society. The Journal's web site is located at http://pubs.acs.org/journal/jafcauen_US
dc.relation.ispartofJournal of Agricultural and Food Chemistryen_US
dc.subject.meshAcetophenones - Chemistry - Isolation & Purificationen_US
dc.subject.meshAngiosperms - Chemistryen_US
dc.subject.meshAntineoplastic Agents, Phytogenic - Chemistry - Isolation & Purification - Toxicityen_US
dc.subject.meshCell Division - Drug Effectsen_US
dc.subject.meshCell Survival - Drug Effectsen_US
dc.subject.meshDna, Neoplasm - Biosynthesis - Drug Effectsen_US
dc.subject.meshGlycosides - Chemistry - Isolation & Purificationen_US
dc.subject.meshHl-60 Cellsen_US
dc.subject.meshHumansen_US
dc.subject.meshLamiaceae - Chemistryen_US
dc.subject.meshMolecular Structureen_US
dc.titleAcetophenone glycosides from thyme (Thymus vulgaris L.)en_US
dc.typeArticleen_US
dc.identifier.emailWang, M: mfwang@hku.hken_US
dc.identifier.authorityWang, M=rp00800en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1021/jf981282den_US
dc.identifier.pmid10552470-
dc.identifier.scopuseid_2-s2.0-0032821909en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032821909&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume47en_US
dc.identifier.issue5en_US
dc.identifier.spage1911en_US
dc.identifier.epage1914en_US
dc.identifier.isiWOS:000080427200019-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWang, M=7406691844en_US
dc.identifier.scopusauthoridKikuzaki, H=7003452974en_US
dc.identifier.scopusauthoridLin, CC=9432378600en_US
dc.identifier.scopusauthoridKahyaoglu, A=6506584601en_US
dc.identifier.scopusauthoridHuang, MT=7404259758en_US
dc.identifier.scopusauthoridNakatani, N=7102434865en_US
dc.identifier.scopusauthoridHo, CT=7404652573en_US

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