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- Publisher Website: 10.1016/0016-6480(87)90194-8
- Scopus: eid_2-s2.0-0023409160
- PMID: 3666413
- WOS: WOS:A1987J813400014
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Article: Ontogenesis of immunocytochemically demonstrable somatotrophs in the adenohypophyseal pars distalis of the developing chick embryo
Title | Ontogenesis of immunocytochemically demonstrable somatotrophs in the adenohypophyseal pars distalis of the developing chick embryo |
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Authors | |
Issue Date | 1987 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen |
Citation | General And Comparative Endocrinology, 1987, v. 67 n. 3, p. 390-398 How to Cite? |
Abstract | Growth hormone (GH)-containing cells in the hypophyseal pars distalis of the chick embryo were identified immunohistochemically using anti-chicken GH sera. GH cells are first demonstrable in Rathke's Pouch as early as Day 4.5 of incubation. By Day 9.5, when the two lobes (rostral and caudal) of the pars distalis are easily recognized, GH cells are confined exclusively to the caudal lobe. Although the number of GH cells increases gradually during embryonic development, there is a statistically significant difference between Days 10.5 and 12.5 in both the cellular density and the percentage of somatotrophs. GH cells, which contain coarse granules evenly distributed throughout the cytoplasm, varied in diameter from 9.3 μm on Day 4.5 to 11.8 μm on Day 20.5, while the nuclear diameter of these cells increased from 2.8 μm on Day 4.5 to 4.9 μm on Day 20.5. There was a statistically significant difference in the nuclear/cytoplasmic ratio between Days 4.5 and 13.5 and between Days 13.5 and 20.5 of incubation. Aspects of the regulation of growth hormone synthesis and secretion in the chick embryo are discussed. © 1987. |
Persistent Identifier | http://hdl.handle.net/10722/178459 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.616 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Thommes, RC | en_US |
dc.contributor.author | Umporowicz, DM | en_US |
dc.contributor.author | Leung, FC | en_US |
dc.contributor.author | Woods, JE | en_US |
dc.date.accessioned | 2012-12-19T09:47:49Z | - |
dc.date.available | 2012-12-19T09:47:49Z | - |
dc.date.issued | 1987 | en_US |
dc.identifier.citation | General And Comparative Endocrinology, 1987, v. 67 n. 3, p. 390-398 | en_US |
dc.identifier.issn | 0016-6480 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/178459 | - |
dc.description.abstract | Growth hormone (GH)-containing cells in the hypophyseal pars distalis of the chick embryo were identified immunohistochemically using anti-chicken GH sera. GH cells are first demonstrable in Rathke's Pouch as early as Day 4.5 of incubation. By Day 9.5, when the two lobes (rostral and caudal) of the pars distalis are easily recognized, GH cells are confined exclusively to the caudal lobe. Although the number of GH cells increases gradually during embryonic development, there is a statistically significant difference between Days 10.5 and 12.5 in both the cellular density and the percentage of somatotrophs. GH cells, which contain coarse granules evenly distributed throughout the cytoplasm, varied in diameter from 9.3 μm on Day 4.5 to 11.8 μm on Day 20.5, while the nuclear diameter of these cells increased from 2.8 μm on Day 4.5 to 4.9 μm on Day 20.5. There was a statistically significant difference in the nuclear/cytoplasmic ratio between Days 4.5 and 13.5 and between Days 13.5 and 20.5 of incubation. Aspects of the regulation of growth hormone synthesis and secretion in the chick embryo are discussed. © 1987. | en_US |
dc.language | eng | en_US |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen | en_US |
dc.relation.ispartof | General and Comparative Endocrinology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Chick Embryo | en_US |
dc.subject.mesh | Growth Hormone - Analysis - Immunology | en_US |
dc.subject.mesh | Immunohistochemistry | en_US |
dc.subject.mesh | Pituitary Gland, Anterior - Cytology - Embryology | en_US |
dc.title | Ontogenesis of immunocytochemically demonstrable somatotrophs in the adenohypophyseal pars distalis of the developing chick embryo | en_US |
dc.type | Article | en_US |
dc.identifier.email | Leung, FC: fcleung@hkucc.hku.hk | en_US |
dc.identifier.authority | Leung, FC=rp00731 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0016-6480(87)90194-8 | - |
dc.identifier.pmid | 3666413 | - |
dc.identifier.scopus | eid_2-s2.0-0023409160 | en_US |
dc.identifier.volume | 67 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.spage | 390 | en_US |
dc.identifier.epage | 398 | en_US |
dc.identifier.isi | WOS:A1987J813400014 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Thommes, RC=6701851744 | en_US |
dc.identifier.scopusauthorid | Umporowicz, DM=6506206003 | en_US |
dc.identifier.scopusauthorid | Leung, FC=7103078633 | en_US |
dc.identifier.scopusauthorid | Woods, JE=7402318407 | en_US |
dc.identifier.issnl | 0016-6480 | - |