File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.2307/3579752
- Scopus: eid_2-s2.0-0032929897
- PMID: 9973089
- WOS: WOS:000077910400011
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Theoretical and experimental tests of a chromosomal fingerprint for densely ionizing radiation based on F ratios calculated from stable and unstable chromosome aberrations
Title | Theoretical and experimental tests of a chromosomal fingerprint for densely ionizing radiation based on F ratios calculated from stable and unstable chromosome aberrations |
---|---|
Authors | |
Issue Date | 1999 |
Citation | Radiation Research, 1999, v. 151 n. 1, p. 85-91 How to Cite? |
Abstract | In the present study, F ratios for both stable chromosome aberrations, i,e. ratios of translocations to pericentric inversions, and unstable aberrations, i.e. dicentrics and centric rings, were measured using fluorescence in situ hybridization. F ratios for stable aberrations measured after exposure to low (2.89 Gy 60Co γ rays) and high-LET (0.25 Gy 56Fe ions; 1.25 Gy 56Fe ions; 3.0 Gy 12C ions) radiation were 6.5 ± 1.5, 4.7 ± 1.6, 9.3 ± 2.5 and 10.4 ± 3.0, respectively. F ratios for unstable aberrations measured after low (2.89 Gy 60Co γ rays) and high-LET (0.25 Gy S6Fe ions; 3.0 Gy 12C ions) radiations were 6.5 ± 1.6, 6.3 ± 2.3 and 11.1 ± 3.7, respectively. No significant difference between the F ratios for low- and high-LET radiation was found. Further tests on the models for calculation of the F ratio proposed by Brenner and Sachs (Radiat. Res. 140, 134-142, 1994) showed that the F ratio may not be straightforward as a practical fingerprint for densely ionizing radiation. |
Persistent Identifier | http://hdl.handle.net/10722/178261 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.695 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lucas, JN | en_US |
dc.contributor.author | Deng, W | en_US |
dc.contributor.author | Oram, SW | en_US |
dc.contributor.author | Hill, FS | en_US |
dc.contributor.author | Durante, M | en_US |
dc.contributor.author | George, K | en_US |
dc.contributor.author | Wu, H | en_US |
dc.contributor.author | Owens, CL | en_US |
dc.contributor.author | Yang, T | en_US |
dc.date.accessioned | 2012-12-19T09:44:50Z | - |
dc.date.available | 2012-12-19T09:44:50Z | - |
dc.date.issued | 1999 | en_US |
dc.identifier.citation | Radiation Research, 1999, v. 151 n. 1, p. 85-91 | en_US |
dc.identifier.issn | 0033-7587 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/178261 | - |
dc.description.abstract | In the present study, F ratios for both stable chromosome aberrations, i,e. ratios of translocations to pericentric inversions, and unstable aberrations, i.e. dicentrics and centric rings, were measured using fluorescence in situ hybridization. F ratios for stable aberrations measured after exposure to low (2.89 Gy 60Co γ rays) and high-LET (0.25 Gy 56Fe ions; 1.25 Gy 56Fe ions; 3.0 Gy 12C ions) radiation were 6.5 ± 1.5, 4.7 ± 1.6, 9.3 ± 2.5 and 10.4 ± 3.0, respectively. F ratios for unstable aberrations measured after low (2.89 Gy 60Co γ rays) and high-LET (0.25 Gy S6Fe ions; 3.0 Gy 12C ions) radiations were 6.5 ± 1.6, 6.3 ± 2.3 and 11.1 ± 3.7, respectively. No significant difference between the F ratios for low- and high-LET radiation was found. Further tests on the models for calculation of the F ratio proposed by Brenner and Sachs (Radiat. Res. 140, 134-142, 1994) showed that the F ratio may not be straightforward as a practical fingerprint for densely ionizing radiation. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Radiation Research | en_US |
dc.subject.mesh | Cells, Cultured | en_US |
dc.subject.mesh | Chromosome Inversion | en_US |
dc.subject.mesh | Chromosomes, Human - Radiation Effects | en_US |
dc.subject.mesh | Dna Fingerprinting | en_US |
dc.subject.mesh | Dose-Response Relationship, Radiation | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | In Situ Hybridization, Fluorescence | en_US |
dc.subject.mesh | Linear Energy Transfer | en_US |
dc.subject.mesh | Lymphocytes - Radiation Effects - Ultrastructure | en_US |
dc.subject.mesh | Translocation, Genetic | en_US |
dc.title | Theoretical and experimental tests of a chromosomal fingerprint for densely ionizing radiation based on F ratios calculated from stable and unstable chromosome aberrations | en_US |
dc.type | Article | en_US |
dc.identifier.email | Deng, W: wdeng@hkucc.hku.hk | en_US |
dc.identifier.authority | Deng, W=rp01640 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.2307/3579752 | en_US |
dc.identifier.pmid | 9973089 | - |
dc.identifier.scopus | eid_2-s2.0-0032929897 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032929897&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 151 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 85 | en_US |
dc.identifier.epage | 91 | en_US |
dc.identifier.isi | WOS:000077910400011 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Lucas, JN=7402441937 | en_US |
dc.identifier.scopusauthorid | Deng, W=7202223673 | en_US |
dc.identifier.scopusauthorid | Oram, SW=36889376000 | en_US |
dc.identifier.scopusauthorid | Hill, FS=35479640200 | en_US |
dc.identifier.scopusauthorid | Durante, M=7004828918 | en_US |
dc.identifier.scopusauthorid | George, K=10639000600 | en_US |
dc.identifier.scopusauthorid | Wu, H=7405584225 | en_US |
dc.identifier.scopusauthorid | Owens, CL=7102511373 | en_US |
dc.identifier.scopusauthorid | Yang, T=36038666400 | en_US |
dc.identifier.issnl | 0033-7587 | - |