File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: 25-Hydroxycholecalciferol and insulin-like growth factor I are determinants of serum concentration of osteocalcin in elderly subjects with and without spinal fractures

Title25-Hydroxycholecalciferol and insulin-like growth factor I are determinants of serum concentration of osteocalcin in elderly subjects with and without spinal fractures
Authors
Issue Date1990
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/bone
Citation
Bone, 1990, v. 11 n. 6, p. 397-400 How to Cite?
AbstractOsteocalcin is one of the major proteins in the osseous matrix. To evaluate the determinants and thus the physiological control of osteocalcin production in normal and osteoporotic subjects, the serum levels of osteocalcin, 25-hydroxycholecalciferol (25-OH-D 3), and insulin-like growth factor I (IGFI) were measured by radioimmunoassay in 44 subjects over 60 years old. Circulating osteocalcin, 25-OH-D 3, and IGFI were 0.28 ± 0.10 nmol/L (1.65 ± 0.96 ng/mL), 70.5 ± 25.1 nmol/L (28.3 ± 10.1 ng/mL), and 23.8 ± 12.0 nmol/L in 27 healthy controls respectively, as compared with 0.09 ± 0.09 nmol/L (0.52 ± 0.52 ng/mL), 48.2 ± 19.9 nmol/L (19.35 ± 7.91 ng/mL), and 16.56 ± 6.96 nmol/L in 17 patients with spinal fractures. Significant correlation was found between osteocalcin and 25-OH-D 3 level, as well as between osteocalcin and IGFI. The results show that IGFI and 25-OH-D 3 are important determinants for serum concentration of osteocalcin in elderly subjects with and without spinal fractures.
Persistent Identifierhttp://hdl.handle.net/10722/178178
ISSN
2015 Impact Factor: 3.736
2015 SCImago Journal Rankings: 1.752
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPun, KKen_US
dc.contributor.authorLau, Pen_US
dc.contributor.authorWong, FHWen_US
dc.contributor.authorCheng, CLen_US
dc.contributor.authorPun, WKen_US
dc.contributor.authorChow, SPen_US
dc.contributor.authorLeong, JCYen_US
dc.date.accessioned2012-12-19T09:43:16Z-
dc.date.available2012-12-19T09:43:16Z-
dc.date.issued1990en_US
dc.identifier.citationBone, 1990, v. 11 n. 6, p. 397-400en_US
dc.identifier.issn8756-3282en_US
dc.identifier.urihttp://hdl.handle.net/10722/178178-
dc.description.abstractOsteocalcin is one of the major proteins in the osseous matrix. To evaluate the determinants and thus the physiological control of osteocalcin production in normal and osteoporotic subjects, the serum levels of osteocalcin, 25-hydroxycholecalciferol (25-OH-D 3), and insulin-like growth factor I (IGFI) were measured by radioimmunoassay in 44 subjects over 60 years old. Circulating osteocalcin, 25-OH-D 3, and IGFI were 0.28 ± 0.10 nmol/L (1.65 ± 0.96 ng/mL), 70.5 ± 25.1 nmol/L (28.3 ± 10.1 ng/mL), and 23.8 ± 12.0 nmol/L in 27 healthy controls respectively, as compared with 0.09 ± 0.09 nmol/L (0.52 ± 0.52 ng/mL), 48.2 ± 19.9 nmol/L (19.35 ± 7.91 ng/mL), and 16.56 ± 6.96 nmol/L in 17 patients with spinal fractures. Significant correlation was found between osteocalcin and 25-OH-D 3 level, as well as between osteocalcin and IGFI. The results show that IGFI and 25-OH-D 3 are important determinants for serum concentration of osteocalcin in elderly subjects with and without spinal fractures.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/boneen_US
dc.relation.ispartofBoneen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCalcifediol - Blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInsulin-Like Growth Factor I - Analysis - Metabolismen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshOsteocalcin - Blooden_US
dc.subject.meshOsteoporosis - Blood - Complicationsen_US
dc.subject.meshRadioimmunoassayen_US
dc.subject.meshSpinal Fractures - Blood - Etiologyen_US
dc.title25-Hydroxycholecalciferol and insulin-like growth factor I are determinants of serum concentration of osteocalcin in elderly subjects with and without spinal fracturesen_US
dc.typeArticleen_US
dc.identifier.emailChow, SP: spchow@hku.hken_US
dc.identifier.authorityChow, SP=rp00064en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/8756-3282(90)90133-Jen_US
dc.identifier.pmid2078433-
dc.identifier.scopuseid_2-s2.0-0025637798en_US
dc.identifier.volume11en_US
dc.identifier.issue6en_US
dc.identifier.spage397en_US
dc.identifier.epage400en_US
dc.identifier.isiWOS:A1990EK85400003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridPun, KK=7006538877en_US
dc.identifier.scopusauthoridLau, P=7102543485en_US
dc.identifier.scopusauthoridWong, FHW=7201409760en_US
dc.identifier.scopusauthoridCheng, CL=7404797794en_US
dc.identifier.scopusauthoridPun, WK=7003726073en_US
dc.identifier.scopusauthoridChow, SP=7201828376en_US
dc.identifier.scopusauthoridLeong, JCY=35560782200en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats