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Article: The inner segment/outer segment junction: What have we learnt so far?

TitleThe inner segment/outer segment junction: What have we learnt so far?
Authors
KeywordsCone Outer Segment Tips
External Limiting Membrane
Inner Segment/Outer Segment Junction
Spectral Domain Optical Coherence Tomography
Verhoeff's Membrane
Issue Date2012
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-ophthalmology.com
Citation
Current Opinion In Ophthalmology, 2012, v. 23 n. 3, p. 210-218 How to Cite?
AbstractPURPOSE OF REVIEW: The advancement of optical coherence tomography has improved the resolution of in-vivo images of the retina. This has led to a wealth of novel knowledge regarding the microstructures of the photoreceptor layer and its relationship with visual functions under different pathological diseases. RECENT FINDINGS: Identification of the hyperreflective lines in the photoreceptor layer has been made possible by spectral domain optical coherence tomography. The inner segment/outer segment junction, external limiting membrane, cone outer segment tips, and the retinal pigment epithelium were thought to be the origins of the four hyperreflective lines seen in the photoreceptor layer. Integrity of these lines has been linked with visual functions in various retinopathies, and has been suggested to carry prognostic implications. Recovery of initially interrupted lines has been documented following successful treatment. SUMMARY: Identification of these hyperreflective lines may have clinical implications as visual function was found to correlate closely with their integrity. Restoration of these lines may indicate treatment response and potential visual recovery. © 2012 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/176485
ISSN
2015 Impact Factor: 2.968
2015 SCImago Journal Rankings: 1.827
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, IYen_US
dc.contributor.authorIu, LPen_US
dc.contributor.authorKoizumi, Hen_US
dc.contributor.authorLai, WWen_US
dc.date.accessioned2012-11-26T09:11:43Z-
dc.date.available2012-11-26T09:11:43Z-
dc.date.issued2012en_US
dc.identifier.citationCurrent Opinion In Ophthalmology, 2012, v. 23 n. 3, p. 210-218en_US
dc.identifier.issn1040-8738en_US
dc.identifier.urihttp://hdl.handle.net/10722/176485-
dc.description.abstractPURPOSE OF REVIEW: The advancement of optical coherence tomography has improved the resolution of in-vivo images of the retina. This has led to a wealth of novel knowledge regarding the microstructures of the photoreceptor layer and its relationship with visual functions under different pathological diseases. RECENT FINDINGS: Identification of the hyperreflective lines in the photoreceptor layer has been made possible by spectral domain optical coherence tomography. The inner segment/outer segment junction, external limiting membrane, cone outer segment tips, and the retinal pigment epithelium were thought to be the origins of the four hyperreflective lines seen in the photoreceptor layer. Integrity of these lines has been linked with visual functions in various retinopathies, and has been suggested to carry prognostic implications. Recovery of initially interrupted lines has been documented following successful treatment. SUMMARY: Identification of these hyperreflective lines may have clinical implications as visual function was found to correlate closely with their integrity. Restoration of these lines may indicate treatment response and potential visual recovery. © 2012 Lippincott Williams & Wilkins, Inc.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-ophthalmology.comen_US
dc.relation.ispartofCurrent Opinion in Ophthalmologyen_US
dc.subjectCone Outer Segment Tipsen_US
dc.subjectExternal Limiting Membraneen_US
dc.subjectInner Segment/Outer Segment Junctionen_US
dc.subjectSpectral Domain Optical Coherence Tomographyen_US
dc.subjectVerhoeff's Membraneen_US
dc.titleThe inner segment/outer segment junction: What have we learnt so far?en_US
dc.typeArticleen_US
dc.identifier.emailWong, IY: wongyhi@hku.hken_US
dc.identifier.emailLai, WW: wicolai@hku.hken_US
dc.identifier.authorityWong, IY=rp01467en_US
dc.identifier.authorityLai, WW=rp00531en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/ICU.0b013e3283524162en_US
dc.identifier.pmid22450219-
dc.identifier.scopuseid_2-s2.0-84859710188en_US
dc.identifier.hkuros207490-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84859710188&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue3en_US
dc.identifier.spage210en_US
dc.identifier.epage218en_US
dc.identifier.eissn1531-7021-
dc.identifier.isiWOS:000303386000008-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWong, IY=36490557200en_US
dc.identifier.scopusauthoridIu, LP=55183455900en_US
dc.identifier.scopusauthoridKoizumi, H=35422424000en_US
dc.identifier.scopusauthoridLai, WW=7402231098en_US

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