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Article: The clinical outcomes of cataract extraction by phacoemulsification in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract: A prospective case series

TitleThe clinical outcomes of cataract extraction by phacoemulsification in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract: A prospective case series
Authors
Issue Date2006
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.com
Citation
Journal Of Glaucoma, 2006, v. 15 n. 1, p. 47-52 How to Cite?
AbstractPurpose: To evaluate the clinical outcomes of minimally invasive cataract extraction by phacoemulsification, with primary intraocular lens implantation, in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract. Materials and Methods: Consecutive primary angle-closure glaucoma patients with co-existing visually significant cataract were invited to participate in this prospective study. After obtaining informed consent, cataract extraction by phacoemulsification through a clear corneal incision was performed under topical anesthesia. Foldable intraocular lenses were implanted in the same setting. These patients were then followed up for a minimum of 1 year. Outcome measures included intraocular pressure (IOP), requirement for glaucoma drugs, and visual acuity. Results: Twenty-one primary angle-closure glaucoma eyes of 21 patients were recruited. Mean age (± SD) was 73.7 ± 8.1 years (range, 60-87 years). There were 12 female patients and 9 male patients, with 13 right eyes and 8 left eyes. Nine eyes (42.9%) had history of acute primary angle closure. Mean follow-up duration was 20.7 ± 3.6 months (range, 13-26 months). Intraocular pressure was decreased from a mean preoperative level of 19.7 ± 6.1 mm Hg (range, 11 mm Hg-40 mm Hg) to 15.5 ± 3.9 mm Hg (range, 9 mm Hg-26 mm Hg) at final follow-up (P = 0.022) (paired t test). The number of glaucoma eye drops required was decreased from a mean preoperative level of 1.91 ± 0.77 (range, 1-3) to 0.52 ± 0.87 (range, 0-3) at final follow-up (P < 0.001) (paired t test), In 10 eyes (47.6%), visual acuity improved significantly after surgery. In 9 eyes (42.9%), visual acuity remained the same. In 2 eyes (9.5%), visual acuity deteriorated significantly after surgery. Mean cup-to-disc ratio was 0.6 ± 0.2 (range, 0.3-0.9) preoperatively, and 0.7 ± 0.2 (range, 0.3-0.9) postoperatively (P = 0.047) (paired t test). Conclusions: In primary angle-closure glaucoma patients with co-existing cataract, cataract extraction alone (by phacoemulsification) can significantly reduce both intraocular pressure and the requirement for glaucoma drugs. Copyright © 2006 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/176436
ISSN
2015 Impact Factor: 2.102
2015 SCImago Journal Rankings: 1.477
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLai, JSMen_US
dc.contributor.authorTham, CCYen_US
dc.contributor.authorChan, JCHen_US
dc.date.accessioned2012-11-26T09:11:16Z-
dc.date.available2012-11-26T09:11:16Z-
dc.date.issued2006en_US
dc.identifier.citationJournal Of Glaucoma, 2006, v. 15 n. 1, p. 47-52en_US
dc.identifier.issn1057-0829en_US
dc.identifier.urihttp://hdl.handle.net/10722/176436-
dc.description.abstractPurpose: To evaluate the clinical outcomes of minimally invasive cataract extraction by phacoemulsification, with primary intraocular lens implantation, in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract. Materials and Methods: Consecutive primary angle-closure glaucoma patients with co-existing visually significant cataract were invited to participate in this prospective study. After obtaining informed consent, cataract extraction by phacoemulsification through a clear corneal incision was performed under topical anesthesia. Foldable intraocular lenses were implanted in the same setting. These patients were then followed up for a minimum of 1 year. Outcome measures included intraocular pressure (IOP), requirement for glaucoma drugs, and visual acuity. Results: Twenty-one primary angle-closure glaucoma eyes of 21 patients were recruited. Mean age (± SD) was 73.7 ± 8.1 years (range, 60-87 years). There were 12 female patients and 9 male patients, with 13 right eyes and 8 left eyes. Nine eyes (42.9%) had history of acute primary angle closure. Mean follow-up duration was 20.7 ± 3.6 months (range, 13-26 months). Intraocular pressure was decreased from a mean preoperative level of 19.7 ± 6.1 mm Hg (range, 11 mm Hg-40 mm Hg) to 15.5 ± 3.9 mm Hg (range, 9 mm Hg-26 mm Hg) at final follow-up (P = 0.022) (paired t test). The number of glaucoma eye drops required was decreased from a mean preoperative level of 1.91 ± 0.77 (range, 1-3) to 0.52 ± 0.87 (range, 0-3) at final follow-up (P < 0.001) (paired t test), In 10 eyes (47.6%), visual acuity improved significantly after surgery. In 9 eyes (42.9%), visual acuity remained the same. In 2 eyes (9.5%), visual acuity deteriorated significantly after surgery. Mean cup-to-disc ratio was 0.6 ± 0.2 (range, 0.3-0.9) preoperatively, and 0.7 ± 0.2 (range, 0.3-0.9) postoperatively (P = 0.047) (paired t test). Conclusions: In primary angle-closure glaucoma patients with co-existing cataract, cataract extraction alone (by phacoemulsification) can significantly reduce both intraocular pressure and the requirement for glaucoma drugs. Copyright © 2006 by Lippincott Williams & Wilkins.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.glaucomajournal.comen_US
dc.relation.ispartofJournal of Glaucomaen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAntihypertensive Agents - Administration & Dosageen_US
dc.subject.meshCataract - Complicationsen_US
dc.subject.meshDrug Utilizationen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Angle-Closure - Complications - Drug Therapy - Physiopathologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressure - Physiologyen_US
dc.subject.meshLens Implantation, Intraocularen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPhacoemulsification - Methodsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSurgical Procedures, Minimally Invasiveen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.titleThe clinical outcomes of cataract extraction by phacoemulsification in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract: A prospective case seriesen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/01.ijg.0000196619.34368.0aen_US
dc.identifier.pmid16378018-
dc.identifier.scopuseid_2-s2.0-30344434313en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-30344434313&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume15en_US
dc.identifier.issue1en_US
dc.identifier.spage47en_US
dc.identifier.epage52en_US
dc.identifier.isiWOS:000234671700010-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridChan, JCH=26024354100en_US

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