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Article: Immediate argon laser peripheral iridoplasty (ALPI) as initial treatment for acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction: A preliminary study

TitleImmediate argon laser peripheral iridoplasty (ALPI) as initial treatment for acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction: A preliminary study
Authors
Issue Date2005
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eye
Citation
Eye, 2005, v. 19 n. 7, p. 778-783 How to Cite?
AbstractPurpose: To study the safety and efficacy of immediate argon laser peripheral iridoplasty (ALPI) as initial treatment of acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction. Methods: In all, 10 consecutive patients with acute phacomorphic angle-closure and intraocular pressure (IOP) ≥40 mmHg were recruited into the study. Each patient received topical atropine (1%) and timolol (0.5%), and immediate ALPI as initial treatment The IOP at 15, 30, 60, and 120 min, and then 1 day, after ALPI were documented by applanation tonometry. Systemic IOP-lowering drugs were only started if IOP remained above 40 mmHg at 2 h after ALPI. Cataract extraction was subsequently performed as definitive treatment. Results: In total, 10 patients (five male, five female), with a mean age ± SD of 73.1 ± 10.3 years were recruited. Mean duration of symptomatic attack was 128 ± 232 h. After ALPI, the mean IOP was reduced from 56.1 ± 12.5 to 45.3 ± 14.5 mmHg at 15 min, 37.6 ± 7.5 mmHg at 30 min, 34.2 ± 9.7 mmHg at 60 min, 25.5 ± 8.7 mmHg at 120 min, and 13.6 ± 4.2 mmHg at 1 day. In one patient, systemic acetazolamide was administered, because the IOP remained above 40 mmHg at 2 h after ALPI. All 10 patients had uncomplicated cataract extraction performed within 4 days after ALPI. No complications from the laser procedure were encountered. Conclusion: Immediate ALPI, replacing systemic antiglaucomatous medications, appeared to be safe and effective as first-line treatment of acute phacomorphic angle-closure. © 2005 Nature Publishing Group All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/176423
ISSN
2015 Impact Factor: 2.213
2015 SCImago Journal Rankings: 1.132
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTham, CCYen_US
dc.contributor.authorLai, JSMen_US
dc.contributor.authorPoon, ASYen_US
dc.contributor.authorChan, JCHen_US
dc.contributor.authorLam, SWen_US
dc.contributor.authorChua, JKHen_US
dc.contributor.authorLam, DSCen_US
dc.date.accessioned2012-11-26T09:11:11Z-
dc.date.available2012-11-26T09:11:11Z-
dc.date.issued2005en_US
dc.identifier.citationEye, 2005, v. 19 n. 7, p. 778-783en_US
dc.identifier.issn0950-222Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/176423-
dc.description.abstractPurpose: To study the safety and efficacy of immediate argon laser peripheral iridoplasty (ALPI) as initial treatment of acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction. Methods: In all, 10 consecutive patients with acute phacomorphic angle-closure and intraocular pressure (IOP) ≥40 mmHg were recruited into the study. Each patient received topical atropine (1%) and timolol (0.5%), and immediate ALPI as initial treatment The IOP at 15, 30, 60, and 120 min, and then 1 day, after ALPI were documented by applanation tonometry. Systemic IOP-lowering drugs were only started if IOP remained above 40 mmHg at 2 h after ALPI. Cataract extraction was subsequently performed as definitive treatment. Results: In total, 10 patients (five male, five female), with a mean age ± SD of 73.1 ± 10.3 years were recruited. Mean duration of symptomatic attack was 128 ± 232 h. After ALPI, the mean IOP was reduced from 56.1 ± 12.5 to 45.3 ± 14.5 mmHg at 15 min, 37.6 ± 7.5 mmHg at 30 min, 34.2 ± 9.7 mmHg at 60 min, 25.5 ± 8.7 mmHg at 120 min, and 13.6 ± 4.2 mmHg at 1 day. In one patient, systemic acetazolamide was administered, because the IOP remained above 40 mmHg at 2 h after ALPI. All 10 patients had uncomplicated cataract extraction performed within 4 days after ALPI. No complications from the laser procedure were encountered. Conclusion: Immediate ALPI, replacing systemic antiglaucomatous medications, appeared to be safe and effective as first-line treatment of acute phacomorphic angle-closure. © 2005 Nature Publishing Group All rights reserved.en_US
dc.languageengen_US
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/eyeen_US
dc.relation.ispartofEyeen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCataract - Complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Angle-Closure - Etiology - Surgeryen_US
dc.subject.meshHumansen_US
dc.subject.meshIris - Surgeryen_US
dc.subject.meshLaser Therapy - Adverse Effects - Methodsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPhacoemulsificationen_US
dc.subject.meshPilot Projectsen_US
dc.titleImmediate argon laser peripheral iridoplasty (ALPI) as initial treatment for acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction: A preliminary studyen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1038/sj.eye.6701651en_US
dc.identifier.pmid15359230-
dc.identifier.scopuseid_2-s2.0-22744452315en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-22744452315&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume19en_US
dc.identifier.issue7en_US
dc.identifier.spage778en_US
dc.identifier.epage783en_US
dc.identifier.isiWOS:000230304100011-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridPoon, ASY=7103068842en_US
dc.identifier.scopusauthoridChan, JCH=26024354100en_US
dc.identifier.scopusauthoridLam, SW=7402279310en_US
dc.identifier.scopusauthoridChua, JKH=7005163724en_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US
dc.identifier.citeulike241773-

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