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Article: Trabeculectomy with β radiation: Long-term follow-up

TitleTrabeculectomy with β radiation: Long-term follow-up
Authors
Issue Date2003
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ophtha
Citation
Ophthalmology, 2003, v. 110 n. 9, p. 1822-1826 How to Cite?
AbstractPurpose: To evaluate the long-term outcome and complications of trabeculectomy with β radiation. Design: Retrospective noncomparative case series. Participants: Forty-three patients with confirmed primary open-angle glaucoma (POAG), who received trabeculectomy with adjunctive β radiation at the Prince of Wales Hospital between June 1991 and November 1994. Methods: Patients fulfilling the preceding criteria were followed up longitudinally. The visual acuity, intraocular pressure (IOP), bleb morphology, and complications were evaluated. Main Outcome Measures: Visual acuity, IOP, bleb morphology, complications. Results: Forty-three eyes of 43 consecutive Chinese patients were recruited and successfully followed up for a minimum of 7 years. The mean age ± 1 standard deviation (SD) was 60.9 ± 13.0 years. There were 29 males and 14 females. The mean baseline IOP ± 1 SD was 28.3 ± 5.8 mmHg. The mean postoperative IOP ± 1 SD after the initial trabeculectomy was 11.9 ± 4.3 mmHg, and the mean number of preoperative IOP-lowering eyedrops ± 1 SD was reduced from 2.8 ± 0.5 to 0.7 ± 1.0 at 7 years follow-up. The qualified success rate at 7 years follow-up, defined as IOP ≤ 21 mmHg with and without medication(s), was 88.4%. The complete success rate at 7 years defined as IOP ≤ 21 mmHg without medication was 60.7%. Two eyes developed blebitis, and one of them progressed to corneal decompensation after the infection. One eye had hypotony, and one eye had a traumatic ruptured bleb. Twelve eyes (27.9%) developed significant cataract. No corneal ulceration or scleral necrosis was encountered. Conclusions: From this noncomparative study, trabeculectomy with a single dose of 1000 rad β radiation used as an adjunctive measure for POAG in Chinese eyes had achieved a qualified success rate of 88.4% at 7 years. © 2003 by the American Academy of Ophthalmology.
Persistent Identifierhttp://hdl.handle.net/10722/176402
ISSN
2015 Impact Factor: 6.75
2015 SCImago Journal Rankings: 4.745
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLai, JSMen_US
dc.contributor.authorPoon, ASYen_US
dc.contributor.authorTham, CYen_US
dc.contributor.authorLam, DSCen_US
dc.date.accessioned2012-11-26T09:11:02Z-
dc.date.available2012-11-26T09:11:02Z-
dc.date.issued2003en_US
dc.identifier.citationOphthalmology, 2003, v. 110 n. 9, p. 1822-1826en_US
dc.identifier.issn0161-6420en_US
dc.identifier.urihttp://hdl.handle.net/10722/176402-
dc.description.abstractPurpose: To evaluate the long-term outcome and complications of trabeculectomy with β radiation. Design: Retrospective noncomparative case series. Participants: Forty-three patients with confirmed primary open-angle glaucoma (POAG), who received trabeculectomy with adjunctive β radiation at the Prince of Wales Hospital between June 1991 and November 1994. Methods: Patients fulfilling the preceding criteria were followed up longitudinally. The visual acuity, intraocular pressure (IOP), bleb morphology, and complications were evaluated. Main Outcome Measures: Visual acuity, IOP, bleb morphology, complications. Results: Forty-three eyes of 43 consecutive Chinese patients were recruited and successfully followed up for a minimum of 7 years. The mean age ± 1 standard deviation (SD) was 60.9 ± 13.0 years. There were 29 males and 14 females. The mean baseline IOP ± 1 SD was 28.3 ± 5.8 mmHg. The mean postoperative IOP ± 1 SD after the initial trabeculectomy was 11.9 ± 4.3 mmHg, and the mean number of preoperative IOP-lowering eyedrops ± 1 SD was reduced from 2.8 ± 0.5 to 0.7 ± 1.0 at 7 years follow-up. The qualified success rate at 7 years follow-up, defined as IOP ≤ 21 mmHg with and without medication(s), was 88.4%. The complete success rate at 7 years defined as IOP ≤ 21 mmHg without medication was 60.7%. Two eyes developed blebitis, and one of them progressed to corneal decompensation after the infection. One eye had hypotony, and one eye had a traumatic ruptured bleb. Twelve eyes (27.9%) developed significant cataract. No corneal ulceration or scleral necrosis was encountered. Conclusions: From this noncomparative study, trabeculectomy with a single dose of 1000 rad β radiation used as an adjunctive measure for POAG in Chinese eyes had achieved a qualified success rate of 88.4% at 7 years. © 2003 by the American Academy of Ophthalmology.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ophthaen_US
dc.relation.ispartofOphthalmologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAsian Continental Ancestry Groupen_US
dc.subject.meshBeta Particlesen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshGlaucoma, Open-Angle - Ethnology - Radiotherapy - Surgeryen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressureen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRadiotherapy, Adjuvanten_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshStrontium Radioisotopes - Therapeutic Useen_US
dc.subject.meshTrabecular Meshwork - Radiation Effects - Surgeryen_US
dc.subject.meshTrabeculectomy - Methodsen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.subject.meshVisual Fieldsen_US
dc.titleTrabeculectomy with β radiation: Long-term follow-upen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0161-6420(03)00561-Xen_US
dc.identifier.pmid13129883-
dc.identifier.scopuseid_2-s2.0-0041930804en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0041930804&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume110en_US
dc.identifier.issue9en_US
dc.identifier.spage1822en_US
dc.identifier.epage1826en_US
dc.identifier.isiWOS:000184950200025-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US
dc.identifier.scopusauthoridPoon, ASY=7103068842en_US
dc.identifier.scopusauthoridTham, CY=36798095500en_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US

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