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Article: Efficacy and safety of immediate anterior chamber paracentesis in the treatment of acute primary angle-closure glaucoma: A pilot study

TitleEfficacy and safety of immediate anterior chamber paracentesis in the treatment of acute primary angle-closure glaucoma: A pilot study
Authors
Issue Date2002
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ophtha
Citation
Ophthalmology, 2002, v. 109 n. 1, p. 64-70 How to Cite?
AbstractObjective: To study the safety and effectiveness of immediate anterior chamber paracentesis, combined with antiglaucomatous medications, in the intraocular pressure control and relief of symptoms of acute primary angle-closure glaucoma (PACG). Design: Prospective noncomparative case series. Participants: Eight consecutive patients with their first attack of acute PACG, with intraocular pressure ≥50 mmHg, were recruited into the study. Intervention: On presentation, each patient received topical pilocarpine (4%) and timolol (0.5%), immediate anterior chamber paracentesis, and systemic acetazolamide and mannitol as primary treatment. The intraocular pressures at 15 and 30 minutes, and then at 1, 2, 3, 12, and 24 hours, were documented by applanation tonometry. Main Outcome Measures: Symptoms, visual acuity, intraocular pressure, corneal edema, angle status on gonioscopy, pupillary size, and reaction. Results: Ten eyes of eight patients seen with acute PACG were recruited. The mean intraocular pressure was reduced from 66.6 ± 9.1 mmHg to 15.1 ± 3.5 mmHg immediately after paracentesis, and then to 17.1 ± 7.0 mmHg at 15 minutes, 21.7 ± 10.2 mmHg at 30 minutes, 22.7 ± 11.0 mmHg at 1 hour, and 20.1 ± 14.6 mmHg at 2 hours after paracentesis. The mean intraocular pressure was less than 21 mmHg at 2 hours and beyond. There was instant symptomatic relief for all patients. No complications from the paracentesis were encountered. Conclusions: From this preliminary study, immediate paracentesis seems to be safe and effective in controlling the intraocular pressure and eliminating symptoms in acute PACG. © 2002 by the American Academy of Ophthalmology.
Persistent Identifierhttp://hdl.handle.net/10722/176378
ISSN
2015 Impact Factor: 6.75
2015 SCImago Journal Rankings: 4.745
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, DSCen_US
dc.contributor.authorChua, JKHen_US
dc.contributor.authorTham, CCYen_US
dc.contributor.authorLai, JSMen_US
dc.date.accessioned2012-11-26T09:10:55Z-
dc.date.available2012-11-26T09:10:55Z-
dc.date.issued2002en_US
dc.identifier.citationOphthalmology, 2002, v. 109 n. 1, p. 64-70en_US
dc.identifier.issn0161-6420en_US
dc.identifier.urihttp://hdl.handle.net/10722/176378-
dc.description.abstractObjective: To study the safety and effectiveness of immediate anterior chamber paracentesis, combined with antiglaucomatous medications, in the intraocular pressure control and relief of symptoms of acute primary angle-closure glaucoma (PACG). Design: Prospective noncomparative case series. Participants: Eight consecutive patients with their first attack of acute PACG, with intraocular pressure ≥50 mmHg, were recruited into the study. Intervention: On presentation, each patient received topical pilocarpine (4%) and timolol (0.5%), immediate anterior chamber paracentesis, and systemic acetazolamide and mannitol as primary treatment. The intraocular pressures at 15 and 30 minutes, and then at 1, 2, 3, 12, and 24 hours, were documented by applanation tonometry. Main Outcome Measures: Symptoms, visual acuity, intraocular pressure, corneal edema, angle status on gonioscopy, pupillary size, and reaction. Results: Ten eyes of eight patients seen with acute PACG were recruited. The mean intraocular pressure was reduced from 66.6 ± 9.1 mmHg to 15.1 ± 3.5 mmHg immediately after paracentesis, and then to 17.1 ± 7.0 mmHg at 15 minutes, 21.7 ± 10.2 mmHg at 30 minutes, 22.7 ± 11.0 mmHg at 1 hour, and 20.1 ± 14.6 mmHg at 2 hours after paracentesis. The mean intraocular pressure was less than 21 mmHg at 2 hours and beyond. There was instant symptomatic relief for all patients. No complications from the paracentesis were encountered. Conclusions: From this preliminary study, immediate paracentesis seems to be safe and effective in controlling the intraocular pressure and eliminating symptoms in acute PACG. © 2002 by the American Academy of Ophthalmology.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/ophthaen_US
dc.relation.ispartofOphthalmologyen_US
dc.subject.meshAcetazolamide - Administration & Dosageen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdrenergic Beta-Antagonists - Administration & Dosageen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAnterior Chamber - Surgeryen_US
dc.subject.meshCarbonic Anhydrase Inhibitors - Administration & Dosageen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlaucoma, Angle-Closure - Physiopathology - Therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshIntraocular Pressureen_US
dc.subject.meshMaleen_US
dc.subject.meshMannitol - Administration & Dosageen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMiotics - Administration & Dosageen_US
dc.subject.meshParacentesis - Methodsen_US
dc.subject.meshPilocarpine - Administration & Dosageen_US
dc.subject.meshPilot Projectsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSafetyen_US
dc.subject.meshTimolol - Administration & Dosageen_US
dc.subject.meshVisual Acuityen_US
dc.titleEfficacy and safety of immediate anterior chamber paracentesis in the treatment of acute primary angle-closure glaucoma: A pilot studyen_US
dc.typeArticleen_US
dc.identifier.emailLai, JSM: laism@hku.hken_US
dc.identifier.authorityLai, JSM=rp00295en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0161-6420(01)00857-0en_US
dc.identifier.pmid11772581-
dc.identifier.scopuseid_2-s2.0-0036135614en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036135614&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume109en_US
dc.identifier.issue1en_US
dc.identifier.spage64en_US
dc.identifier.epage70en_US
dc.identifier.isiWOS:000173056400023-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLam, DSC=35500200200en_US
dc.identifier.scopusauthoridChua, JKH=7005163724en_US
dc.identifier.scopusauthoridTham, CCY=7006081241en_US
dc.identifier.scopusauthoridLai, JSM=7401939748en_US

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