File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Evidence of a non-vagal mechanism of pancreatic polypeptide release in man

TitleEvidence of a non-vagal mechanism of pancreatic polypeptide release in man
Authors
Issue Date1981
Citation
Italian Journal Of Gastroenterology, 1981, v. 13 n. 4, p. 244-247 How to Cite?
AbstractThe Pancreatic polypeptide (PP) response to a protein meal was measured in 10 healthy volunteers, 10 duodenal ulcer patients, and 6 gastrectomized patients. No significant differences were found between normal and duodenal ulcer subjects, whereas, in gastrectomized patients, basal and food-stimulated plasma PP concentrations were significantly lower (p<0.05). The latter patients, although lacking vagal innervation, showed significantly increased PP levels (p<0.05) 30 min after the beginning of the meal. However, the same secretory pattern related to baseline levels was recorded in all groups: an inverse correlation between basal PP output and stimulated PP output/basal PP output was noted. These results indicate that a humoral mechanism is probably involved in the release of PP, and, furthermore, that neural and paracrine factors may contribute to the regulation of basal and food-stimulated PP concentrations.
Persistent Identifierhttp://hdl.handle.net/10722/176236
ISSN
1997 Impact Factor: 0.383

 

DC FieldValueLanguage
dc.contributor.authorAnnibale, Ben_US
dc.contributor.authorBruzzone, Ren_US
dc.contributor.authorSeveri, Cen_US
dc.date.accessioned2012-11-26T09:07:28Z-
dc.date.available2012-11-26T09:07:28Z-
dc.date.issued1981en_US
dc.identifier.citationItalian Journal Of Gastroenterology, 1981, v. 13 n. 4, p. 244-247en_US
dc.identifier.issn0392-0623en_US
dc.identifier.urihttp://hdl.handle.net/10722/176236-
dc.description.abstractThe Pancreatic polypeptide (PP) response to a protein meal was measured in 10 healthy volunteers, 10 duodenal ulcer patients, and 6 gastrectomized patients. No significant differences were found between normal and duodenal ulcer subjects, whereas, in gastrectomized patients, basal and food-stimulated plasma PP concentrations were significantly lower (p<0.05). The latter patients, although lacking vagal innervation, showed significantly increased PP levels (p<0.05) 30 min after the beginning of the meal. However, the same secretory pattern related to baseline levels was recorded in all groups: an inverse correlation between basal PP output and stimulated PP output/basal PP output was noted. These results indicate that a humoral mechanism is probably involved in the release of PP, and, furthermore, that neural and paracrine factors may contribute to the regulation of basal and food-stimulated PP concentrations.en_US
dc.languageengen_US
dc.relation.ispartofItalian Journal of Gastroenterologyen_US
dc.titleEvidence of a non-vagal mechanism of pancreatic polypeptide release in manen_US
dc.typeArticleen_US
dc.identifier.emailBruzzone, R: bruzzone@hkucc.hku.hken_US
dc.identifier.authorityBruzzone, R=rp01442en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0019810890en_US
dc.identifier.volume13en_US
dc.identifier.issue4en_US
dc.identifier.spage244en_US
dc.identifier.epage247en_US
dc.identifier.scopusauthoridAnnibale, B=7005102706en_US
dc.identifier.scopusauthoridBruzzone, R=7006793327en_US
dc.identifier.scopusauthoridSeveri, C=6604099156en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats