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Conference Paper: Genes, viruses and neurodevelopmental schizophrenia

TitleGenes, viruses and neurodevelopmental schizophrenia
Authors
Issue Date1992
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/jpsychires
Citation
Journal Of Psychiatric Research, 1992, v. 26 n. 4, p. 225-235 How to Cite?
AbstractRecent neuroimaging and neuropathological studies suggest a developmental origin for schizophrenia. Some cases may, therefore, be caused by a genetic defect in the specification of brain development. Early environmental hazards such as obstetric complications, and maternal exposure during pregnancy to influenza epidemics, have also been found to increase the risk of later schizophrenia. The relationship between the prevalence of influenza and birth date has been found more consistently for female than male schizophrenics. Female schizophrenia is also associated with a higher risk of schizophrenia in first degree relatives. This raises the question of whether part of the genetic predisposition to schizophrenia may comprise an abnormal reaction to maternal influenza.
Persistent Identifierhttp://hdl.handle.net/10722/176088
ISSN
2015 Impact Factor: 4.465
2015 SCImago Journal Rankings: 2.265
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMurray, RMen_US
dc.contributor.authorJones, Pen_US
dc.contributor.authorO'callaghan, Een_US
dc.contributor.authorTakei, Nen_US
dc.contributor.authorSham, Pen_US
dc.date.accessioned2012-11-26T09:05:32Z-
dc.date.available2012-11-26T09:05:32Z-
dc.date.issued1992en_US
dc.identifier.citationJournal Of Psychiatric Research, 1992, v. 26 n. 4, p. 225-235en_US
dc.identifier.issn0022-3956en_US
dc.identifier.urihttp://hdl.handle.net/10722/176088-
dc.description.abstractRecent neuroimaging and neuropathological studies suggest a developmental origin for schizophrenia. Some cases may, therefore, be caused by a genetic defect in the specification of brain development. Early environmental hazards such as obstetric complications, and maternal exposure during pregnancy to influenza epidemics, have also been found to increase the risk of later schizophrenia. The relationship between the prevalence of influenza and birth date has been found more consistently for female than male schizophrenics. Female schizophrenia is also associated with a higher risk of schizophrenia in first degree relatives. This raises the question of whether part of the genetic predisposition to schizophrenia may comprise an abnormal reaction to maternal influenza.en_US
dc.languageengen_US
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/jpsychiresen_US
dc.relation.ispartofJournal of Psychiatric Researchen_US
dc.subject.meshBrain Damage, Chronic - Genetics - Psychologyen_US
dc.subject.meshCerebral Cortex - Pathologyen_US
dc.subject.meshCerebral Ventricles - Pathologyen_US
dc.subject.meshDelirium, Dementia, Amnestic, Cognitive Disorders - Genetics - Psychologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshOrthomyxoviridae - Geneticsen_US
dc.subject.meshPersonality Developmenten_US
dc.subject.meshPregnancyen_US
dc.subject.meshPrenatal Exposure Delayed Effectsen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSchizophrenia - Geneticsen_US
dc.subject.meshSchizophrenic Psychologyen_US
dc.subject.meshSocial Environmenten_US
dc.titleGenes, viruses and neurodevelopmental schizophreniaen_US
dc.typeConference_Paperen_US
dc.identifier.emailSham, P: pcsham@hku.hken_US
dc.identifier.authoritySham, P=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0022-3956(92)90029-Nen_US
dc.identifier.pmid1491349-
dc.identifier.scopuseid_2-s2.0-0027103179en_US
dc.identifier.volume26en_US
dc.identifier.issue4en_US
dc.identifier.spage225en_US
dc.identifier.epage235en_US
dc.identifier.isiWOS:A1992KH01900002-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridMurray, RM=35406239400en_US
dc.identifier.scopusauthoridJones, P=36078972900en_US
dc.identifier.scopusauthoridO'Callaghan, E=7005694363en_US
dc.identifier.scopusauthoridTakei, N=35874982900en_US
dc.identifier.scopusauthoridSham, P=34573429300en_US

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