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- Publisher Website: 10.1016/j.jclinepi.2005.11.008
- Scopus: eid_2-s2.0-33646019272
- PMID: 16632133
- WOS: WOS:000237481600003
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Article: Small-scale randomized controlled trials need more powerful methods of mediational analysis than the Baron-Kenny method
Title | Small-scale randomized controlled trials need more powerful methods of mediational analysis than the Baron-Kenny method |
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Authors | |
Keywords | Exercise-related social support Mediational effect Randomized controlled trials Small sample Statistical power Walking |
Issue Date | 2006 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jclinepi |
Citation | Journal Of Clinical Epidemiology, 2006, v. 59 n. 5, p. 457-464 How to Cite? |
Abstract | Objective: To devise more-effective physical activity interventions, the mediating mechanisms yielding behavioral change need to be identified. The Baron-Kenny method is most commonly used, but has low statistical power and may not identify mechanisms of behavioral change in small-to-medium size studies. More powerful statistical tests are available. Study Design and Setting: Inactive adults (N = 52) were randomized to either a print or a print-plus-telephone intervention. Walking and exercise-related social support were assessed at baseline, after the intervention, and 4 weeks later. The Baron-Kenny and three alternative methods of mediational analysis (Freedman-Schatzkin; MacKinnon et al.; bootstrap method) were used to examine the effects of social support on initial behavior change and maintenance. Results: A significant mediational effect of social support on initial behavior change was indicated by the MacKinnon et al., bootstrap, and, marginally, Freedman-Schatzkin methods, but not by the Baron-Kenny method. No significant mediational effect of social support on maintenance of walking was found. Conclusions: Methodologically rigorous intervention studies to identify mediators of change in physical activity are costly and labor intensive, and may not be feasible with large samples. The use of statistically powerful tests of mediational effects in small-scale studies can inform the development of more effective interventions. © 2006 Elsevier Inc. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/176030 |
ISSN | 2023 Impact Factor: 7.3 2023 SCImago Journal Rankings: 2.888 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Cerin, E | en_US |
dc.contributor.author | Taylor, LM | en_US |
dc.contributor.author | Leslie, E | en_US |
dc.contributor.author | Owen, N | en_US |
dc.date.accessioned | 2012-11-26T09:04:36Z | - |
dc.date.available | 2012-11-26T09:04:36Z | - |
dc.date.issued | 2006 | en_US |
dc.identifier.citation | Journal Of Clinical Epidemiology, 2006, v. 59 n. 5, p. 457-464 | en_US |
dc.identifier.issn | 0895-4356 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/176030 | - |
dc.description.abstract | Objective: To devise more-effective physical activity interventions, the mediating mechanisms yielding behavioral change need to be identified. The Baron-Kenny method is most commonly used, but has low statistical power and may not identify mechanisms of behavioral change in small-to-medium size studies. More powerful statistical tests are available. Study Design and Setting: Inactive adults (N = 52) were randomized to either a print or a print-plus-telephone intervention. Walking and exercise-related social support were assessed at baseline, after the intervention, and 4 weeks later. The Baron-Kenny and three alternative methods of mediational analysis (Freedman-Schatzkin; MacKinnon et al.; bootstrap method) were used to examine the effects of social support on initial behavior change and maintenance. Results: A significant mediational effect of social support on initial behavior change was indicated by the MacKinnon et al., bootstrap, and, marginally, Freedman-Schatzkin methods, but not by the Baron-Kenny method. No significant mediational effect of social support on maintenance of walking was found. Conclusions: Methodologically rigorous intervention studies to identify mediators of change in physical activity are costly and labor intensive, and may not be feasible with large samples. The use of statistically powerful tests of mediational effects in small-scale studies can inform the development of more effective interventions. © 2006 Elsevier Inc. All rights reserved. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/jclinepi | en_US |
dc.relation.ispartof | Journal of Clinical Epidemiology | en_US |
dc.subject | Exercise-related social support | - |
dc.subject | Mediational effect | - |
dc.subject | Randomized controlled trials | - |
dc.subject | Small sample | - |
dc.subject | Statistical power | - |
dc.subject | Walking | - |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Exercise | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Health Behavior | en_US |
dc.subject.mesh | Health Education | en_US |
dc.subject.mesh | Health Promotion | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Models, Statistical | en_US |
dc.subject.mesh | Social Support | en_US |
dc.subject.mesh | Telephone | en_US |
dc.subject.mesh | Walking | en_US |
dc.title | Small-scale randomized controlled trials need more powerful methods of mediational analysis than the Baron-Kenny method | en_US |
dc.type | Article | en_US |
dc.identifier.email | Cerin, E: ecerin@hku.hk | en_US |
dc.identifier.authority | Cerin, E=rp00890 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/j.jclinepi.2005.11.008 | en_US |
dc.identifier.pmid | 16632133 | - |
dc.identifier.scopus | eid_2-s2.0-33646019272 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-33646019272&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 59 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 457 | en_US |
dc.identifier.epage | 464 | en_US |
dc.identifier.isi | WOS:000237481600003 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Cerin, E=14522064200 | en_US |
dc.identifier.scopusauthorid | Taylor, LM=13009043300 | en_US |
dc.identifier.scopusauthorid | Leslie, E=7004928143 | en_US |
dc.identifier.scopusauthorid | Owen, N=7102307209 | en_US |
dc.identifier.issnl | 0895-4356 | - |