File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Lack of association between TaqI A1 allele of dopamine D2 receptor gene and methamphetamine abuse or psychosis in Chinese

TitleLack of association between TaqI A1 allele of dopamine D2 receptor gene and methamphetamine abuse or psychosis in Chinese
Authors
Issue Date2001
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0148-7299:1/
Citation
American Journal Of Medical Genetics - Neuropsychiatric Genetics, 2001, v. 105 n. 7, p. 629-630 How to Cite?
AbstractThe reasons why some methamphetamine (MAMP)abusers develop psychotic symptoms, whilst others do not despite prolonged MAMP usage, are not clear. Previous studies examining association between DRD2 TaqI Al and substance abuse or psychosis have produced intriguing results. We set out to examine if the Al plays a major role in predisposing individuals to MAMP abuse and/or MAMP abusers to MAMP psychosis. A total of 412 Chinese MAMP abusers were recruited from a psychiatric hospital and a detention center in Taipei, and assessed with the Diagnostic Interview for Genetic Studies (DIGS). Six of them were diagnosed to have MAMP intoxication with perceptual but not MAMP psychosis. The others were divided into those with a lifetime diagnosis of MAMP psychosis as psychotic abusers (N=154) and those without as non-psychotic abusers (N = 252). There was no significant difference in Al allele frequency between the psychotic and the non-psychotic abusers (44% versus 39%, alpha = 2.4, df = 1, P = 0.12), nor between the MAMP abusers and 432 unrelated normal controls of the same ethnicity (41% versus 43%, alpha = 0.6, df = 1, P = 0.43). The results do not support DRD2 TaqI Al play a major role in either MAMP abuse or MAMP psychosis in Chinese.
Persistent Identifierhttp://hdl.handle.net/10722/175955
ISSN
2015 Impact Factor: 3.391
2015 SCImago Journal Rankings: 1.771

 

DC FieldValueLanguage
dc.contributor.authorChen, CKen_US
dc.contributor.authorLin, SKen_US
dc.contributor.authorLoh, EWen_US
dc.contributor.authorBall, Den_US
dc.contributor.authorSham, Pen_US
dc.contributor.authorMurray, RMen_US
dc.date.accessioned2012-11-26T09:02:52Z-
dc.date.available2012-11-26T09:02:52Z-
dc.date.issued2001en_US
dc.identifier.citationAmerican Journal Of Medical Genetics - Neuropsychiatric Genetics, 2001, v. 105 n. 7, p. 629-630en_US
dc.identifier.issn1552-4841en_US
dc.identifier.urihttp://hdl.handle.net/10722/175955-
dc.description.abstractThe reasons why some methamphetamine (MAMP)abusers develop psychotic symptoms, whilst others do not despite prolonged MAMP usage, are not clear. Previous studies examining association between DRD2 TaqI Al and substance abuse or psychosis have produced intriguing results. We set out to examine if the Al plays a major role in predisposing individuals to MAMP abuse and/or MAMP abusers to MAMP psychosis. A total of 412 Chinese MAMP abusers were recruited from a psychiatric hospital and a detention center in Taipei, and assessed with the Diagnostic Interview for Genetic Studies (DIGS). Six of them were diagnosed to have MAMP intoxication with perceptual but not MAMP psychosis. The others were divided into those with a lifetime diagnosis of MAMP psychosis as psychotic abusers (N=154) and those without as non-psychotic abusers (N = 252). There was no significant difference in Al allele frequency between the psychotic and the non-psychotic abusers (44% versus 39%, alpha = 2.4, df = 1, P = 0.12), nor between the MAMP abusers and 432 unrelated normal controls of the same ethnicity (41% versus 43%, alpha = 0.6, df = 1, P = 0.43). The results do not support DRD2 TaqI Al play a major role in either MAMP abuse or MAMP psychosis in Chinese.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0148-7299:1/en_US
dc.relation.ispartofAmerican Journal of Medical Genetics - Neuropsychiatric Geneticsen_US
dc.titleLack of association between TaqI A1 allele of dopamine D2 receptor gene and methamphetamine abuse or psychosis in Chineseen_US
dc.typeArticleen_US
dc.identifier.emailSham, P: pcsham@hku.hken_US
dc.identifier.authoritySham, P=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33749091684en_US
dc.identifier.volume105en_US
dc.identifier.issue7en_US
dc.identifier.spage629en_US
dc.identifier.epage630en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChen, CK=7501961684en_US
dc.identifier.scopusauthoridLin, SK=7407607751en_US
dc.identifier.scopusauthoridLoh, EW=7102994165en_US
dc.identifier.scopusauthoridBall, D=7202703810en_US
dc.identifier.scopusauthoridSham, P=34573429300en_US
dc.identifier.scopusauthoridMurray, RM=35406239400en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats