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Article: Properties of structured association approaches to detecting population stratification

TitleProperties of structured association approaches to detecting population stratification
Authors
Issue Date2004
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/HHE
Citation
Human Heredity, 2004, v. 58 n. 2, p. 93-107 How to Cite?
AbstractObjective: To examine the properties of the structured association approach for the detection and correction of population stratification. Method: A method is developed, within a latent class analysis framework, similar to the methods proposed by Satten et al. (2001) and Pritchard et al. (2000). A series of simulations illustrate the relative impact of number and type of loci, sample size and population structure. Results: The ability to detect stratification and assign individuals to population strata is determined for a number of different scenarios. Conclusion: The results underline the importance of careful marker selection. Copyright © 2004 S. Karger AG.
Persistent Identifierhttp://hdl.handle.net/10722/175926
ISSN
2015 Impact Factor: 1.539
2015 SCImago Journal Rankings: 0.942
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPurcell, Sen_US
dc.contributor.authorSham, Pen_US
dc.date.accessioned2012-11-26T09:02:34Z-
dc.date.available2012-11-26T09:02:34Z-
dc.date.issued2004en_US
dc.identifier.citationHuman Heredity, 2004, v. 58 n. 2, p. 93-107en_US
dc.identifier.issn0001-5652en_US
dc.identifier.urihttp://hdl.handle.net/10722/175926-
dc.description.abstractObjective: To examine the properties of the structured association approach for the detection and correction of population stratification. Method: A method is developed, within a latent class analysis framework, similar to the methods proposed by Satten et al. (2001) and Pritchard et al. (2000). A series of simulations illustrate the relative impact of number and type of loci, sample size and population structure. Results: The ability to detect stratification and assign individuals to population strata is determined for a number of different scenarios. Conclusion: The results underline the importance of careful marker selection. Copyright © 2004 S. Karger AG.en_US
dc.languageengen_US
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/HHEen_US
dc.relation.ispartofHuman Heredityen_US
dc.subject.meshAlgorithmsen_US
dc.subject.meshComputer Simulationen_US
dc.subject.meshData Interpretation, Statisticalen_US
dc.subject.meshGene Frequencyen_US
dc.subject.meshGenetics, Population - Statistics & Numerical Dataen_US
dc.subject.meshHumansen_US
dc.subject.meshLinkage Disequilibriumen_US
dc.titleProperties of structured association approaches to detecting population stratificationen_US
dc.typeArticleen_US
dc.identifier.emailSham, P: pcsham@hku.hken_US
dc.identifier.authoritySham, P=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1159/000083030en_US
dc.identifier.pmid15711089-
dc.identifier.scopuseid_2-s2.0-18444396148en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-18444396148&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume58en_US
dc.identifier.issue2en_US
dc.identifier.spage93en_US
dc.identifier.epage107en_US
dc.identifier.isiWOS:000226979500005-
dc.publisher.placeSwitzerlanden_US
dc.identifier.scopusauthoridPurcell, S=7005489464en_US
dc.identifier.scopusauthoridSham, P=34573429300en_US

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