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Article: Do schizophrenic patients who managed to get to university have a non-developmental form of illness?

TitleDo schizophrenic patients who managed to get to university have a non-developmental form of illness?
Authors
Issue Date2002
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=PSM
Citation
Psychological Medicine, 2002, v. 32 n. 3, p. 535-544 How to Cite?
AbstractBackground. Many people who develop schizophrenia have impairments in intellectual and social functioning that are detectable from early childhood. However, some patients do not exhibit such deficits, and this suggests that they may have suffered less neurodevelopmental damage. We hypothesized that the aetiology and form of schizophrenia may differ in such patients. We therefore studied a group of schizophrenic patients who were functioning well enough to enter university prior to illness onset. Methods. The casenotes of 46 university-educated patients and 48 non-university-educated patients were rated on several schedules including the OPCRIT checklist, and the two groups were compared using univariate statistical techniques. Principal components analysis was then performed using data from all patients, and the factor scores for each principal component were compared between groups. Results. Univariate analyses showed the university-educated patients had an excess of depressive symptoms, and a paucity of core schizophrenic symptoms. Four principal components emerged in the principal components analysis: mania, biological depression, schizophrenic symptoms, and a reactive depression. University-educated patients scored significantly higher on the reactive depression principal component, and lower on the schizophrenic symptoms principal component, than the non-university-educated patients. Conclusions. University-educated patients may have a non-developmental subtype of schizophrenia.
Persistent Identifierhttp://hdl.handle.net/10722/175860
ISSN
2015 Impact Factor: 5.491
2015 SCImago Journal Rankings: 2.843
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMaccabe, JHen_US
dc.contributor.authorAldouri, Een_US
dc.contributor.authorFahy, TAen_US
dc.contributor.authorSham, PCen_US
dc.contributor.authorMurray, RMen_US
dc.date.accessioned2012-11-26T09:01:52Z-
dc.date.available2012-11-26T09:01:52Z-
dc.date.issued2002en_US
dc.identifier.citationPsychological Medicine, 2002, v. 32 n. 3, p. 535-544en_US
dc.identifier.issn0033-2917en_US
dc.identifier.urihttp://hdl.handle.net/10722/175860-
dc.description.abstractBackground. Many people who develop schizophrenia have impairments in intellectual and social functioning that are detectable from early childhood. However, some patients do not exhibit such deficits, and this suggests that they may have suffered less neurodevelopmental damage. We hypothesized that the aetiology and form of schizophrenia may differ in such patients. We therefore studied a group of schizophrenic patients who were functioning well enough to enter university prior to illness onset. Methods. The casenotes of 46 university-educated patients and 48 non-university-educated patients were rated on several schedules including the OPCRIT checklist, and the two groups were compared using univariate statistical techniques. Principal components analysis was then performed using data from all patients, and the factor scores for each principal component were compared between groups. Results. Univariate analyses showed the university-educated patients had an excess of depressive symptoms, and a paucity of core schizophrenic symptoms. Four principal components emerged in the principal components analysis: mania, biological depression, schizophrenic symptoms, and a reactive depression. University-educated patients scored significantly higher on the reactive depression principal component, and lower on the schizophrenic symptoms principal component, than the non-university-educated patients. Conclusions. University-educated patients may have a non-developmental subtype of schizophrenia.en_US
dc.languageengen_US
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=PSMen_US
dc.relation.ispartofPsychological Medicineen_US
dc.subject.meshAdjustment Disorders - Diagnosis - Etiology - Psychologyen_US
dc.subject.meshAdulten_US
dc.subject.meshBipolar Disorder - Diagnosis - Etiology - Psychologyen_US
dc.subject.meshBrain Damage, Chronic - Diagnosis - Etiology - Psychologyen_US
dc.subject.meshEducational Statusen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshPrognosisen_US
dc.subject.meshPsychiatric Status Rating Scalesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSchizophrenia - Diagnosis - Etiologyen_US
dc.subject.meshSchizophrenic Psychologyen_US
dc.subject.meshUniversitiesen_US
dc.titleDo schizophrenic patients who managed to get to university have a non-developmental form of illness?en_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1017/S0033291702005391en_US
dc.identifier.pmid11989998-
dc.identifier.scopuseid_2-s2.0-0036225936en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036225936&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume32en_US
dc.identifier.issue3en_US
dc.identifier.spage535en_US
dc.identifier.epage544en_US
dc.identifier.isiWOS:000175077400014-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridMacCabe, JH=7003607616en_US
dc.identifier.scopusauthoridAldouri, E=6504255103en_US
dc.identifier.scopusauthoridFahy, TA=8077630100en_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US
dc.identifier.scopusauthoridMurray, RM=35406239400en_US

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