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- Publisher Website: 10.1159/000022901
- Scopus: eid_2-s2.0-0033990339
- PMID: 10799972
- WOS: WOS:000084056600006
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Article: Model-free analysis and permutation tests for allelic associations
Title | Model-free analysis and permutation tests for allelic associations |
---|---|
Authors | |
Keywords | Allelic association Case-control design Haplotype analysis Model-free association analysis Permutation test |
Issue Date | 2000 |
Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/HHE |
Citation | Human Heredity, 2000, v. 50 n. 2, p. 133-139 How to Cite? |
Abstract | In this short report, we address some practical problems in performing likelihood-based allelic association analysis of case-control data. Model-free statistics are proposed and their properties assessed by simulation, and procedures based on permutation tests are described for marker-marker as well as marker-disease associations. A memory-efficient algorithm is developed which enables several highly polymorphic markers to be analysed. |
Persistent Identifier | http://hdl.handle.net/10722/175821 |
ISSN | 2023 Impact Factor: 1.1 2023 SCImago Journal Rankings: 0.483 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zhao, JH | en_US |
dc.contributor.author | Curtis, D | en_US |
dc.contributor.author | Sham, PC | en_US |
dc.date.accessioned | 2012-11-26T09:01:34Z | - |
dc.date.available | 2012-11-26T09:01:34Z | - |
dc.date.issued | 2000 | en_US |
dc.identifier.citation | Human Heredity, 2000, v. 50 n. 2, p. 133-139 | en_US |
dc.identifier.issn | 0001-5652 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/175821 | - |
dc.description.abstract | In this short report, we address some practical problems in performing likelihood-based allelic association analysis of case-control data. Model-free statistics are proposed and their properties assessed by simulation, and procedures based on permutation tests are described for marker-marker as well as marker-disease associations. A memory-efficient algorithm is developed which enables several highly polymorphic markers to be analysed. | en_US |
dc.language | eng | en_US |
dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/HHE | en_US |
dc.relation.ispartof | Human Heredity | en_US |
dc.subject | Allelic association | - |
dc.subject | Case-control design | - |
dc.subject | Haplotype analysis | - |
dc.subject | Model-free association analysis | - |
dc.subject | Permutation test | - |
dc.subject.mesh | Algorithms | en_US |
dc.subject.mesh | Alleles | en_US |
dc.subject.mesh | Genotype | en_US |
dc.subject.mesh | Haplotypes | en_US |
dc.subject.mesh | Models, Genetic | en_US |
dc.subject.mesh | Software | en_US |
dc.title | Model-free analysis and permutation tests for allelic associations | en_US |
dc.type | Article | en_US |
dc.identifier.email | Sham, PC: pcsham@hku.hk | en_US |
dc.identifier.authority | Sham, PC=rp00459 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1159/000022901 | - |
dc.identifier.pmid | 10799972 | - |
dc.identifier.scopus | eid_2-s2.0-0033990339 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0033990339&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 50 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 133 | en_US |
dc.identifier.epage | 139 | en_US |
dc.identifier.isi | WOS:000084056600006 | - |
dc.publisher.place | Switzerland | en_US |
dc.identifier.scopusauthorid | Zhao, JH=7410311266 | en_US |
dc.identifier.scopusauthorid | Curtis, D=14633020700 | en_US |
dc.identifier.scopusauthorid | Sham, PC=34573429300 | en_US |
dc.identifier.issnl | 0001-5652 | - |