File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Prenatal exposure to the 1957 influenza epidemic and adult schizophrenia: A follow-up study

TitlePrenatal exposure to the 1957 influenza epidemic and adult schizophrenia: A follow-up study
Authors
Issue Date1996
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
Citation
British Journal Of Psychiatry, 1996, v. 168 MAR., p. 368-371 How to Cite?
AbstractBackground. We investigated the hypothesis that prenatal exposure to the 1957 A2 influenza increases the risk of schizophrenia in adulthood. Method. We traced a cohort of individuals known to have been exposed to the 1957 influenza epidemic during gestation and an unexposed cohort matched for period of gestation and hospital of birth. Follow-up information on psychiatric illness in subjects was sought from two sources: maternal interview and psychiatric hospital admission data. Results. Follow-up information was obtained on 54% of the sample: 238 subjects from the influenza-exposed group and 287 subjects from the unexposed group. There was no increased risk of schizophrenia among the exposed cohort compared to the unexposed cohort (relative risk 1.1; 95% CI 0.41-2.95), although there was an increase in depressive illness (relative risk 1.59; 95% CI 1.15-2.19). Conclusions. The association between prenatal influenza and an increased risk of schizophrenia in adulthood has thus far been found only in population based data and is not supported by the present observational study which has information about exposure and outcome in individuals.
Persistent Identifierhttp://hdl.handle.net/10722/175747
ISSN
2015 Impact Factor: 7.06
2015 SCImago Journal Rankings: 2.674
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCannon, Men_US
dc.contributor.authorCotter, Den_US
dc.contributor.authorCoffey, VPen_US
dc.contributor.authorSham, PCen_US
dc.contributor.authorTakei, Nen_US
dc.contributor.authorLarkin, Cen_US
dc.contributor.authorMurray, RMen_US
dc.contributor.authorO'callaghan, Een_US
dc.date.accessioned2012-11-26T09:00:56Z-
dc.date.available2012-11-26T09:00:56Z-
dc.date.issued1996en_US
dc.identifier.citationBritish Journal Of Psychiatry, 1996, v. 168 MAR., p. 368-371en_US
dc.identifier.issn0007-1250en_US
dc.identifier.urihttp://hdl.handle.net/10722/175747-
dc.description.abstractBackground. We investigated the hypothesis that prenatal exposure to the 1957 A2 influenza increases the risk of schizophrenia in adulthood. Method. We traced a cohort of individuals known to have been exposed to the 1957 influenza epidemic during gestation and an unexposed cohort matched for period of gestation and hospital of birth. Follow-up information on psychiatric illness in subjects was sought from two sources: maternal interview and psychiatric hospital admission data. Results. Follow-up information was obtained on 54% of the sample: 238 subjects from the influenza-exposed group and 287 subjects from the unexposed group. There was no increased risk of schizophrenia among the exposed cohort compared to the unexposed cohort (relative risk 1.1; 95% CI 0.41-2.95), although there was an increase in depressive illness (relative risk 1.59; 95% CI 1.15-2.19). Conclusions. The association between prenatal influenza and an increased risk of schizophrenia in adulthood has thus far been found only in population based data and is not supported by the present observational study which has information about exposure and outcome in individuals.en_US
dc.languageengen_US
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/en_US
dc.relation.ispartofBritish Journal of Psychiatryen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshInfluenza, Human - Epidemiologyen_US
dc.subject.meshIreland - Epidemiologyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPrenatal Careen_US
dc.subject.meshPrenatal Exposure Delayed Effectsen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSchizophrenia - Etiologyen_US
dc.titlePrenatal exposure to the 1957 influenza epidemic and adult schizophrenia: A follow-up studyen_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1192/bjp.168.3.368-
dc.identifier.pmid8833694-
dc.identifier.scopuseid_2-s2.0-0029898371en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0029898371&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume168en_US
dc.identifier.issueMAR.en_US
dc.identifier.spage368en_US
dc.identifier.epage371en_US
dc.identifier.isiWOS:A1996UA07700019-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridCannon, M=7202419754en_US
dc.identifier.scopusauthoridCotter, D=7101938570en_US
dc.identifier.scopusauthoridCoffey, VP=7003654613en_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US
dc.identifier.scopusauthoridTakei, N=35874982900en_US
dc.identifier.scopusauthoridLarkin, C=7006768069en_US
dc.identifier.scopusauthoridMurray, RM=35406239400en_US
dc.identifier.scopusauthoridO'Callaghan, E=7005694363en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats