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Article: A review and reanalysis of Bruno Schulz's 'Erkrankungsalter schizophrener Eltern und Kinder [Age at onset of illness in schizophrenic parents and offspring]:' Zeitschriff fur die gesamte Neurologie und Psychiatrie, 168, 709-721, 1940

TitleA review and reanalysis of Bruno Schulz's 'Erkrankungsalter schizophrener Eltern und Kinder [Age at onset of illness in schizophrenic parents and offspring]:' Zeitschriff fur die gesamte Neurologie und Psychiatrie, 168, 709-721, 1940
Authors
Issue Date1995
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.psychgenetics.com
Citation
Psychiatric Genetics, 1995, v. 5 n. 2, p. 57-62 How to Cite?
AbstractNearly all previous evidence of the familial transmission of age at onset of schizophrenia has been in siblings and twins. In his paper, Bruno Schulz examined the age at onset distribution of schizophrenia in affected parent and offspring pairs, using a systematic series of ascertained cases (n = 106), as well as a second series of chronic in-patients (n = 36). The parent-offspring correlation in age at onset, for cases with a definite diagnosis in the systematically ascertained series, was estimated at 0.346 (95% confidence interval 0.134, 0.528). Schulz did not test for differences between the two series and between males and females, but our reanalysis, using correlational methods and a mixed linear model, did not detect any significant differences. These results are consistent with previous findings that age at onset of schizophrenia is influenced by familial factors which may be genetic.
Persistent Identifierhttp://hdl.handle.net/10722/175734
ISSN
2015 Impact Factor: 1.736
2015 SCImago Journal Rankings: 0.968
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSham, PCen_US
dc.contributor.authorZerbinRudin, Een_US
dc.contributor.authorKendler, KSen_US
dc.date.accessioned2012-11-26T09:00:50Z-
dc.date.available2012-11-26T09:00:50Z-
dc.date.issued1995en_US
dc.identifier.citationPsychiatric Genetics, 1995, v. 5 n. 2, p. 57-62en_US
dc.identifier.issn0955-8829en_US
dc.identifier.urihttp://hdl.handle.net/10722/175734-
dc.description.abstractNearly all previous evidence of the familial transmission of age at onset of schizophrenia has been in siblings and twins. In his paper, Bruno Schulz examined the age at onset distribution of schizophrenia in affected parent and offspring pairs, using a systematic series of ascertained cases (n = 106), as well as a second series of chronic in-patients (n = 36). The parent-offspring correlation in age at onset, for cases with a definite diagnosis in the systematically ascertained series, was estimated at 0.346 (95% confidence interval 0.134, 0.528). Schulz did not test for differences between the two series and between males and females, but our reanalysis, using correlational methods and a mixed linear model, did not detect any significant differences. These results are consistent with previous findings that age at onset of schizophrenia is influenced by familial factors which may be genetic.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.psychgenetics.comen_US
dc.relation.ispartofPsychiatric Geneticsen_US
dc.subject.meshAdulten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAge Of Onseten_US
dc.subject.meshChilden_US
dc.subject.meshDiseases In Twinsen_US
dc.subject.meshFamilyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGermanyen_US
dc.subject.meshHistory, 20Th Centuryen_US
dc.subject.meshHumansen_US
dc.subject.meshInpatientsen_US
dc.subject.meshMaleen_US
dc.subject.meshPsychiatric Department, Hospitalen_US
dc.subject.meshRegression Analysisen_US
dc.subject.meshSampling Studiesen_US
dc.subject.meshSchizophrenia - Epidemiology - Genetics - Historyen_US
dc.subject.meshSex Distributionen_US
dc.titleA review and reanalysis of Bruno Schulz's 'Erkrankungsalter schizophrener Eltern und Kinder [Age at onset of illness in schizophrenic parents and offspring]:' Zeitschriff fur die gesamte Neurologie und Psychiatrie, 168, 709-721, 1940en_US
dc.typeArticleen_US
dc.identifier.emailSham, PC: pcsham@hku.hken_US
dc.identifier.authoritySham, PC=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00041444-199522000-00002-
dc.identifier.pmid7551963-
dc.identifier.scopuseid_2-s2.0-0029166444en_US
dc.identifier.volume5en_US
dc.identifier.issue2en_US
dc.identifier.spage57en_US
dc.identifier.epage62en_US
dc.identifier.isiWOS:A1995RK76500002-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridSham, PC=34573429300en_US
dc.identifier.scopusauthoridZerbinRudin, E=6701323903en_US
dc.identifier.scopusauthoridKendler, KS=35396760800en_US

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