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Article: Apolipoprotein E genotype and late paraphrenia

TitleApolipoprotein E genotype and late paraphrenia
Authors
KeywordsApolipoprotein E
Late Paraphrenia
Issue Date1995
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294
Citation
International Journal Of Geriatric Psychiatry, 1995, v. 10 n. 2, p. 147-150 How to Cite?
AbstractPatients with late paraphrenia or late onset schizophrenia frequently have associated cognitive impairment which may in some cases progress to a recognized dementia. The frequency of the apoE ε4 allele is high in individuals who develop Alzheimer's disease. Twenty-three patients with late paraphrenia were genotyped for ApoE. The frequency of the ε4 allele was comparable with that found in a large group of centenarians, but lower than previously reported from populations of normal controls and Alzheimer's disease patients. Two out of three male patients tested had the rare ε2/ε2 genotype, which was not found in any of the females.
Persistent Identifierhttp://hdl.handle.net/10722/175719
ISSN
2015 Impact Factor: 2.699
2015 SCImago Journal Rankings: 1.382
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHoward, Ren_US
dc.contributor.authorDennehey, Jen_US
dc.contributor.authorLovestone, Sen_US
dc.contributor.authorBirkett, Jen_US
dc.contributor.authorSham, Pen_US
dc.contributor.authorPowell, Jen_US
dc.contributor.authorCastle, Den_US
dc.contributor.authorMurray, Ren_US
dc.contributor.authorLevy, Ren_US
dc.date.accessioned2012-11-26T09:00:44Z-
dc.date.available2012-11-26T09:00:44Z-
dc.date.issued1995en_US
dc.identifier.citationInternational Journal Of Geriatric Psychiatry, 1995, v. 10 n. 2, p. 147-150en_US
dc.identifier.issn0885-6230en_US
dc.identifier.urihttp://hdl.handle.net/10722/175719-
dc.description.abstractPatients with late paraphrenia or late onset schizophrenia frequently have associated cognitive impairment which may in some cases progress to a recognized dementia. The frequency of the apoE ε4 allele is high in individuals who develop Alzheimer's disease. Twenty-three patients with late paraphrenia were genotyped for ApoE. The frequency of the ε4 allele was comparable with that found in a large group of centenarians, but lower than previously reported from populations of normal controls and Alzheimer's disease patients. Two out of three male patients tested had the rare ε2/ε2 genotype, which was not found in any of the females.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294en_US
dc.relation.ispartofInternational Journal of Geriatric Psychiatryen_US
dc.subjectApolipoprotein Een_US
dc.subjectLate Paraphreniaen_US
dc.titleApolipoprotein E genotype and late paraphreniaen_US
dc.typeArticleen_US
dc.identifier.emailSham, P: pcsham@hku.hken_US
dc.identifier.authoritySham, P=rp00459en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/gps.930100210en_US
dc.identifier.scopuseid_2-s2.0-0028922020en_US
dc.identifier.volume10en_US
dc.identifier.issue2en_US
dc.identifier.spage147en_US
dc.identifier.epage150en_US
dc.identifier.isiWOS:A1995QJ01800009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridHoward, R=34769841900en_US
dc.identifier.scopusauthoridDennehey, J=6505761355en_US
dc.identifier.scopusauthoridLovestone, S=7005575001en_US
dc.identifier.scopusauthoridBirkett, J=7004014779en_US
dc.identifier.scopusauthoridSham, P=34573429300en_US
dc.identifier.scopusauthoridPowell, J=7403541196en_US
dc.identifier.scopusauthoridCastle, D=16149153500en_US
dc.identifier.scopusauthoridMurray, R=35406239400en_US
dc.identifier.scopusauthoridLevy, R=7404060972en_US

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