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- Scopus: eid_2-s2.0-0020385867
- PMID: 7139618
- WOS: WOS:A1982PT10400041
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Article: Biliary control of β-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum
Title | Biliary control of β-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum |
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Authors | |
Issue Date | 1982 |
Publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ |
Citation | Cancer Research, 1982, v. 42 n. 12, p. 5165-5166 How to Cite? |
Abstract | The effect of bile exclusion on intestinal β-glucuronidase activity was studied in the rat. Bile exclusion dramatically decreased the bacterial β-glucuronidase activity in the cecum and rectum but did not affect the normal low level in the ileum. Thus, bile flow may be the most important factor in modulating β-glucuronidase activity in the rat large bowel. Dietary substances which can alter bile flow may thus have effects on intestinal bacterial β-glucuronidase activity. Effects of diet on colon cancer might therefore be explicable in terms of altered bile flow rather than altered bacterial β-glucuronidase induction. |
Persistent Identifier | http://hdl.handle.net/10722/175625 |
ISSN | 2023 Impact Factor: 12.5 2023 SCImago Journal Rankings: 3.468 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Robertson, AM | en_US |
dc.contributor.author | Lee, SP | en_US |
dc.contributor.author | Lindop, R | en_US |
dc.date.accessioned | 2012-11-26T09:00:10Z | - |
dc.date.available | 2012-11-26T09:00:10Z | - |
dc.date.issued | 1982 | en_US |
dc.identifier.citation | Cancer Research, 1982, v. 42 n. 12, p. 5165-5166 | en_US |
dc.identifier.issn | 0008-5472 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/175625 | - |
dc.description.abstract | The effect of bile exclusion on intestinal β-glucuronidase activity was studied in the rat. Bile exclusion dramatically decreased the bacterial β-glucuronidase activity in the cecum and rectum but did not affect the normal low level in the ileum. Thus, bile flow may be the most important factor in modulating β-glucuronidase activity in the rat large bowel. Dietary substances which can alter bile flow may thus have effects on intestinal bacterial β-glucuronidase activity. Effects of diet on colon cancer might therefore be explicable in terms of altered bile flow rather than altered bacterial β-glucuronidase induction. | en_US |
dc.language | eng | en_US |
dc.publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ | en_US |
dc.relation.ispartof | Cancer Research | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Bile - Physiology | en_US |
dc.subject.mesh | Bile Ducts - Physiology | en_US |
dc.subject.mesh | Cecum - Enzymology | en_US |
dc.subject.mesh | Glucuronidase - Metabolism | en_US |
dc.subject.mesh | Ileum - Enzymology | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, Inbred Strains | en_US |
dc.subject.mesh | Rectum - Enzymology | en_US |
dc.title | Biliary control of β-glucuronidase activity in the luminal contents of the rat ileum, cecum, and rectum | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lee, SP: sumlee@hku.hk | en_US |
dc.identifier.authority | Lee, SP=rp01351 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 7139618 | - |
dc.identifier.scopus | eid_2-s2.0-0020385867 | en_US |
dc.identifier.volume | 42 | en_US |
dc.identifier.issue | 12 | en_US |
dc.identifier.spage | 5165 | en_US |
dc.identifier.epage | 5166 | en_US |
dc.identifier.isi | WOS:A1982PT10400041 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Robertson, AM=7403044550 | en_US |
dc.identifier.scopusauthorid | Lee, SP=7601417497 | en_US |
dc.identifier.scopusauthorid | Lindop, R=6506691373 | en_US |
dc.identifier.issnl | 0008-5472 | - |