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Article: Exocrine pancreatic function in hepatic cirrhosis

TitleExocrine pancreatic function in hepatic cirrhosis
Authors
Issue Date1976
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.html
Citation
American Journal Of Gastroenterology, 1976, v. 65 n. 3, p. 244-248 How to Cite?
AbstractExocrine pancreatic function was assessed by the standard test meal method of Lundh in a control group, and 13 patients with nonalcoholic, postnecrotic cirrhosis of the liver. In six of these patients, splenorenal shunts were performed and exocrine pancreatic function was assessed before and three months after operation. In three of the six, the secretin pancreozymin stimulation test was also performed. An increased volume but normal trypsin output was observed in the unoperated cirrhotic patients. An increase both in volume and in trypsin was found in the cirrhotic patients after shunting using the test meal stimulation. There was no appreciable difference, however, when tested with secretin and pancreozymin. Hypersecretion in cirrhotics, with or without shunts, is probably due to a by pass of the hepatic degradation of normal pancreatic secretogogues produced by the intestine.
Persistent Identifierhttp://hdl.handle.net/10722/175596
ISSN
2015 Impact Factor: 10.383
2015 SCImago Journal Rankings: 3.946
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLee, SPen_US
dc.contributor.authorLai, KSen_US
dc.date.accessioned2012-11-26T09:00:04Z-
dc.date.available2012-11-26T09:00:04Z-
dc.date.issued1976en_US
dc.identifier.citationAmerican Journal Of Gastroenterology, 1976, v. 65 n. 3, p. 244-248en_US
dc.identifier.issn0002-9270en_US
dc.identifier.urihttp://hdl.handle.net/10722/175596-
dc.description.abstractExocrine pancreatic function was assessed by the standard test meal method of Lundh in a control group, and 13 patients with nonalcoholic, postnecrotic cirrhosis of the liver. In six of these patients, splenorenal shunts were performed and exocrine pancreatic function was assessed before and three months after operation. In three of the six, the secretin pancreozymin stimulation test was also performed. An increased volume but normal trypsin output was observed in the unoperated cirrhotic patients. An increase both in volume and in trypsin was found in the cirrhotic patients after shunting using the test meal stimulation. There was no appreciable difference, however, when tested with secretin and pancreozymin. Hypersecretion in cirrhotics, with or without shunts, is probably due to a by pass of the hepatic degradation of normal pancreatic secretogogues produced by the intestine.en_US
dc.languageengen_US
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/ajg/index.htmlen_US
dc.relation.ispartofAmerican Journal of Gastroenterologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCholecystokinin - Administration & Dosageen_US
dc.subject.meshEsophageal And Gastric Varices - Surgeryen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis - Physiopathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPancreas - Physiopathologyen_US
dc.subject.meshPancreatic Juice - Secretionen_US
dc.subject.meshSecretin - Administration & Dosageen_US
dc.subject.meshTrypsin - Analysis - Secretionen_US
dc.titleExocrine pancreatic function in hepatic cirrhosisen_US
dc.typeArticleen_US
dc.identifier.emailLee, SP: sumlee@hku.hken_US
dc.identifier.authorityLee, SP=rp01351en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid937324-
dc.identifier.scopuseid_2-s2.0-0017074574en_US
dc.identifier.volume65en_US
dc.identifier.issue3en_US
dc.identifier.spage244en_US
dc.identifier.epage248en_US
dc.identifier.isiWOS:A1976BW10800008-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLee, SP=7601417497en_US
dc.identifier.scopusauthoridLai, KS=7402135546en_US

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