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Article: Combined clinical and cognitive criteria to identify mild cognitive impairment in a southern Chinese community

TitleCombined clinical and cognitive criteria to identify mild cognitive impairment in a southern Chinese community
Authors
KeywordsChinese
Dementia
Mild Cognitive Impairment
Progression
Issue Date2010
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.alzheimerjournal.com
Citation
Alzheimer Disease And Associated Disorders, 2010, v. 24 n. 4, p. 343-347 How to Cite?
AbstractMild Cognitive Impairment (MCI) is a recognized risk condition for clinical dementia. This paper attempted to explore the applicability of a combined cognitive and clinical approach to identify older Chinese adults at-risk of cognitive decline. Seven hundred forty randomly recruited community dwelling participants (aged 60 or over) were assessed at baseline and 2 years with Clinical Dementia Rating (CDR) and a cognitive battery. Baseline MCI groups were categorized by CDR-MCI, cognitive function (Cog-MCI), and a combined CDR-Cog approach. The cognitive approach adopted the Mayo clinic criteria. For the combined approach, nonamnestic MCI combined CDR 0.5 plus nonmemory cognitive deficits. The overall concordance between CDR and Cognitive test ratings were 65.3% (χ 2 = 256.4, P<0.001, κ=0.44). With a combined approach, 424(57%) participants were classified as normal. CDR-MCI group had higher cognitive scores compared with MCI groups by other criteria (1 way analysis of variance or ANOVA). At 2 years, the combined CDR-Cog MCI group identified all dementia (N=24) converters although group differences were not significant. Cognitive function and CDR identified participants potentially at-risk for furthermore decline, but exhibited some differences in detection profiles. A combined approach may be more practical in screening for MCI participants with diverse educational and cultural background. Copyright © 2010 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/174249
ISSN
2015 Impact Factor: 2.53
2015 SCImago Journal Rankings: 1.370
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, LCWen_US
dc.contributor.authorTam, CWCen_US
dc.contributor.authorLeung, GTYen_US
dc.contributor.authorLui, VWCen_US
dc.contributor.authorFung, AWTen_US
dc.contributor.authorChiu, HFKen_US
dc.contributor.authorChan, SSMen_US
dc.contributor.authorChan, WCen_US
dc.contributor.authorNg, Sen_US
dc.contributor.authorChan, WMen_US
dc.date.accessioned2012-11-22T02:01:37Z-
dc.date.available2012-11-22T02:01:37Z-
dc.date.issued2010en_US
dc.identifier.citationAlzheimer Disease And Associated Disorders, 2010, v. 24 n. 4, p. 343-347en_US
dc.identifier.issn0893-0341en_US
dc.identifier.urihttp://hdl.handle.net/10722/174249-
dc.description.abstractMild Cognitive Impairment (MCI) is a recognized risk condition for clinical dementia. This paper attempted to explore the applicability of a combined cognitive and clinical approach to identify older Chinese adults at-risk of cognitive decline. Seven hundred forty randomly recruited community dwelling participants (aged 60 or over) were assessed at baseline and 2 years with Clinical Dementia Rating (CDR) and a cognitive battery. Baseline MCI groups were categorized by CDR-MCI, cognitive function (Cog-MCI), and a combined CDR-Cog approach. The cognitive approach adopted the Mayo clinic criteria. For the combined approach, nonamnestic MCI combined CDR 0.5 plus nonmemory cognitive deficits. The overall concordance between CDR and Cognitive test ratings were 65.3% (χ 2 = 256.4, P<0.001, κ=0.44). With a combined approach, 424(57%) participants were classified as normal. CDR-MCI group had higher cognitive scores compared with MCI groups by other criteria (1 way analysis of variance or ANOVA). At 2 years, the combined CDR-Cog MCI group identified all dementia (N=24) converters although group differences were not significant. Cognitive function and CDR identified participants potentially at-risk for furthermore decline, but exhibited some differences in detection profiles. A combined approach may be more practical in screening for MCI participants with diverse educational and cultural background. Copyright © 2010 by Lippincott Williams & Wilkins.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.alzheimerjournal.comen_US
dc.relation.ispartofAlzheimer Disease and Associated Disordersen_US
dc.subjectChineseen_US
dc.subjectDementiaen_US
dc.subjectMild Cognitive Impairmenten_US
dc.subjectProgressionen_US
dc.titleCombined clinical and cognitive criteria to identify mild cognitive impairment in a southern Chinese communityen_US
dc.typeArticleen_US
dc.identifier.emailChan, WC: waicchan@hku.hken_US
dc.identifier.authorityChan, WC=rp01687en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/WAD.0b013e3181eb2f42en_US
dc.identifier.pmid20693868-
dc.identifier.scopuseid_2-s2.0-78651392568en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78651392568&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue4en_US
dc.identifier.spage343en_US
dc.identifier.epage347en_US
dc.identifier.isiWOS:000284308100006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLam, LCW=7201984627en_US
dc.identifier.scopusauthoridTam, CWC=26021559000en_US
dc.identifier.scopusauthoridLeung, GTY=22980588600en_US
dc.identifier.scopusauthoridLui, VWC=9245605300en_US
dc.identifier.scopusauthoridFung, AWT=22934304800en_US
dc.identifier.scopusauthoridChiu, HFK=24447976700en_US
dc.identifier.scopusauthoridChan, SSM=13409371900en_US
dc.identifier.scopusauthoridChan, WC=16400525900en_US
dc.identifier.scopusauthoridNg, S=36955417000en_US
dc.identifier.scopusauthoridChan, WM=7403914485en_US

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