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Article: Clinical correlates of Parkinsonian signs in community-dwelling Chinese older persons: A population based study

TitleClinical correlates of Parkinsonian signs in community-dwelling Chinese older persons: A population based study
Authors
Issue Date2008
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294
Citation
International Journal Of Geriatric Psychiatry, 2008, v. 23 n. 7, p. 719-725 How to Cite?
AbstractBackground and objective: This study examined the clinical correlates of parkinsonian signs including neuropsychiatric symptoms, cognitive impairment and medical illness burden in the community-dwelling non-demented Chinese elderly. Methods: A random sample of 765 Chinese elderly subjects from a thematic household survey was recruited. There were 389 normal elderly controls (Clinical Dementia Rating [CDR] 0) (NC) and 376 subjects with questionable dementia (CDR 0.5). The subjects with questionable dementia (CDR 0.5) were categorized into two groups: a MCI group (n = 291) and a very mild dementia (VMD) group (n = 85). Parkinsonian signs were measured by Unified Parkinson Disease Rating Scale-motor scale (UPDRS). The clinical correlates were investigated in each group. Results: UPDRS motor score was associated with age, cumulative medical illness burden and cerebrovascular accidents in the normal control and MCI groups. It correlated negatively with MMSE scores in the NC group. It was associated with presence of soft signs in the NC and MCI groups; and apathy in the VMD group. Conclusion: Neuropsychiatric symptoms, cognitive impairment and vascular risk factors had different patterns of associations with parkinsonian signs in the older persons with different degree of cognitive impairment. Copyright © 2008 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/174242
ISSN
2015 Impact Factor: 2.699
2015 SCImago Journal Rankings: 1.382
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTam, CWCen_US
dc.contributor.authorLam, LCWen_US
dc.contributor.authorLui, VWCen_US
dc.contributor.authorChan, WCen_US
dc.contributor.authorChan, SSMen_US
dc.contributor.authorChiu, HFKen_US
dc.contributor.authorChan, WMen_US
dc.date.accessioned2012-11-22T02:01:32Z-
dc.date.available2012-11-22T02:01:32Z-
dc.date.issued2008en_US
dc.identifier.citationInternational Journal Of Geriatric Psychiatry, 2008, v. 23 n. 7, p. 719-725en_US
dc.identifier.issn0885-6230en_US
dc.identifier.urihttp://hdl.handle.net/10722/174242-
dc.description.abstractBackground and objective: This study examined the clinical correlates of parkinsonian signs including neuropsychiatric symptoms, cognitive impairment and medical illness burden in the community-dwelling non-demented Chinese elderly. Methods: A random sample of 765 Chinese elderly subjects from a thematic household survey was recruited. There were 389 normal elderly controls (Clinical Dementia Rating [CDR] 0) (NC) and 376 subjects with questionable dementia (CDR 0.5). The subjects with questionable dementia (CDR 0.5) were categorized into two groups: a MCI group (n = 291) and a very mild dementia (VMD) group (n = 85). Parkinsonian signs were measured by Unified Parkinson Disease Rating Scale-motor scale (UPDRS). The clinical correlates were investigated in each group. Results: UPDRS motor score was associated with age, cumulative medical illness burden and cerebrovascular accidents in the normal control and MCI groups. It correlated negatively with MMSE scores in the NC group. It was associated with presence of soft signs in the NC and MCI groups; and apathy in the VMD group. Conclusion: Neuropsychiatric symptoms, cognitive impairment and vascular risk factors had different patterns of associations with parkinsonian signs in the older persons with different degree of cognitive impairment. Copyright © 2008 John Wiley & Sons, Ltd.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/4294en_US
dc.relation.ispartofInternational Journal of Geriatric Psychiatryen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCardiovascular Diseases - Etiologyen_US
dc.subject.meshCognition Disorders - Etiologyen_US
dc.subject.meshDementia - Complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGeriatric Assessmenten_US
dc.subject.meshHealth Surveysen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeuropsychological Testsen_US
dc.subject.meshParkinson Disease, Secondary - Etiology - Psychologyen_US
dc.subject.meshRisk Factorsen_US
dc.titleClinical correlates of Parkinsonian signs in community-dwelling Chinese older persons: A population based studyen_US
dc.typeArticleen_US
dc.identifier.emailChan, WC: waicchan@hku.hken_US
dc.identifier.authorityChan, WC=rp01687en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/gps.1966en_US
dc.identifier.pmid18213739-
dc.identifier.scopuseid_2-s2.0-48249113729en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-48249113729&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume23en_US
dc.identifier.issue7en_US
dc.identifier.spage719en_US
dc.identifier.epage725en_US
dc.identifier.isiWOS:000257729300009-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridTam, CWC=26021559000en_US
dc.identifier.scopusauthoridLam, LCW=7201984627en_US
dc.identifier.scopusauthoridLui, VWC=9245605300en_US
dc.identifier.scopusauthoridChan, WC=16400525900en_US
dc.identifier.scopusauthoridChan, SSM=13409371900en_US
dc.identifier.scopusauthoridChiu, HFK=7401986628en_US
dc.identifier.scopusauthoridChan, WM=7403918361en_US

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