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Conference Paper: Multivariate analysis of risk factors influencing survival in 110 ethnic Chinese with papillary thyroid cancer

TitleMultivariate analysis of risk factors influencing survival in 110 ethnic Chinese with papillary thyroid cancer
Authors
Issue Date1994
PublisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/
Citation
World Journal Of Surgery, 1994, v. 18 n. 4, p. 547-551 How to Cite?
AbstractData from 110 Chinese patients presenting with papillary thyroid cancer to a single institution up to December 1985 have been analyzed to evaluate the possible risk factors affecting survival. There were 83 women and 27 men with an age range of 15 to 78 years (mean 45 years, median 42 years). The longest follow-up period is 39 years and the median 10 years. Cervical lymph node recurrence more than 6 months after surgery developed in 12 patients, of whom 1 died with a concomitant distant metastasis. 'Thyroid bed' tumor recurrence, after apparently complete surgery, presented in 10 patients and resulted in 5 deaths. Distant metastases were identified in 17 patients with 7 deaths. Another 4 patients died from advanced local disease incompletely resectable on presentation. The following seven risk factors for survival were selected for multivariate analysis: age, sex, tumor size, histologic evidence of extrathyroidal spread, lymph node recurrence, neck recurrence, and distant metastases. Age, size, neck recurrence, and distant metastases were all significant on univariate analysis. Using Cox proportional hazards regression in the multivariate analysis of these seven factors, only age (p < 0.0001) was shown to be significant. Age over 40 years on first diagnosis was a highly significant indicator of high risk (p = 0.0003, log-rank).
Persistent Identifierhttp://hdl.handle.net/10722/173553
ISSN
2015 Impact Factor: 2.523
2015 SCImago Journal Rankings: 1.375
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLorentz, TGen_US
dc.contributor.authorLau, PWKen_US
dc.contributor.authorLo, CYen_US
dc.contributor.authorLaw, WLen_US
dc.contributor.authorWan, KYen_US
dc.contributor.authorLauder, IJen_US
dc.contributor.authorCady, Ben_US
dc.date.accessioned2012-10-30T06:32:56Z-
dc.date.available2012-10-30T06:32:56Z-
dc.date.issued1994en_US
dc.identifier.citationWorld Journal Of Surgery, 1994, v. 18 n. 4, p. 547-551en_US
dc.identifier.issn0364-2313en_US
dc.identifier.urihttp://hdl.handle.net/10722/173553-
dc.description.abstractData from 110 Chinese patients presenting with papillary thyroid cancer to a single institution up to December 1985 have been analyzed to evaluate the possible risk factors affecting survival. There were 83 women and 27 men with an age range of 15 to 78 years (mean 45 years, median 42 years). The longest follow-up period is 39 years and the median 10 years. Cervical lymph node recurrence more than 6 months after surgery developed in 12 patients, of whom 1 died with a concomitant distant metastasis. 'Thyroid bed' tumor recurrence, after apparently complete surgery, presented in 10 patients and resulted in 5 deaths. Distant metastases were identified in 17 patients with 7 deaths. Another 4 patients died from advanced local disease incompletely resectable on presentation. The following seven risk factors for survival were selected for multivariate analysis: age, sex, tumor size, histologic evidence of extrathyroidal spread, lymph node recurrence, neck recurrence, and distant metastases. Age, size, neck recurrence, and distant metastases were all significant on univariate analysis. Using Cox proportional hazards regression in the multivariate analysis of these seven factors, only age (p < 0.0001) was shown to be significant. Age over 40 years on first diagnosis was a highly significant indicator of high risk (p = 0.0003, log-rank).en_US
dc.languageengen_US
dc.publisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/en_US
dc.relation.ispartofWorld Journal of Surgeryen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAgeden_US
dc.subject.meshAsian Continental Ancestry Groupen_US
dc.subject.meshCarcinoma, Papillary - Mortality - Pathologyen_US
dc.subject.meshChina - Ethnologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMultivariate Analysisen_US
dc.subject.meshNeoplasm Metastasisen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThyroid Neoplasms - Mortality - Pathologyen_US
dc.titleMultivariate analysis of risk factors influencing survival in 110 ethnic Chinese with papillary thyroid canceren_US
dc.typeConference_Paperen_US
dc.identifier.emailLaw, WL: lawwl@hkucc.hku.hken_US
dc.identifier.authorityLaw, WL=rp00436en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/BF00353761-
dc.identifier.pmid7725743-
dc.identifier.scopuseid_2-s2.0-0028059307en_US
dc.identifier.volume18en_US
dc.identifier.issue4en_US
dc.identifier.spage547en_US
dc.identifier.epage551en_US
dc.identifier.isiWOS:A1994PD21500016-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLorentz, TG=6602819345en_US
dc.identifier.scopusauthoridLau, PWK=7102543485en_US
dc.identifier.scopusauthoridLo, CY=16417392800en_US
dc.identifier.scopusauthoridLaw, WL=7103147867en_US
dc.identifier.scopusauthoridWan, KY=36848883500en_US
dc.identifier.scopusauthoridLauder, IJ=35564928000en_US
dc.identifier.scopusauthoridCady, B=7103136909en_US

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