File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Scopus: eid_2-s2.0-0026078824
- PMID: 1900447
- WOS: WOS:A1991FB33600011
- Find via
Supplementary
- Citations:
- Appears in Collections:
Conference Paper: Endothelium-dependent contractions
Title | Endothelium-dependent contractions |
---|---|
Authors | |
Keywords | anoxic conditions autoregulatory processes cultured endothelial cells cyclooxygenase EDCF endothelin endothelium-derived contractile factor(s) superoxide anion thromboxane A2 |
Issue Date | 1991 |
Publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/JVR |
Citation | Blood Vessels, 1991, v. 28 n. 1-3, p. 74-83 How to Cite? |
Abstract | The endothelial cells help to control the tone of the underlying vascular smooth muscle by releasing vasoactive factors. In physiological circumstances, the release of relaxing factors (nitric oxide and endothelium-derived hyperpolarizing factor) appears to predominate. However, in certain blood vessels (peripheral veins and large cerebral arteries), the normal endothelium has the propensity to release vasoconstrictor substances, among which are superoxide anion and thromboxane A 2; the release of these endothelium-derived vasoconstrictors may contribute to the autoregulatory processes. In most blood vessels, anoxic conditions initiate the release of an unidentified endothelium-dependent contracting fractor. Cultured endothelial cells, and blood vessels maintained under culture conditions for prolonged periods of time, release the vasoconstrictor peptide endothelin. A characteristic of vascular diseases is that the ability of the endothelial cells to release relaxing factor(s) is reduced, while the generation of contracting factor is maintained or enhanced. |
Persistent Identifier | http://hdl.handle.net/10722/173495 |
ISSN | |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vanhoutte, PM | en_US |
dc.contributor.author | Luscher, TF | en_US |
dc.contributor.author | Graser, T | en_US |
dc.date.accessioned | 2012-10-30T06:32:21Z | - |
dc.date.available | 2012-10-30T06:32:21Z | - |
dc.date.issued | 1991 | en_US |
dc.identifier.citation | Blood Vessels, 1991, v. 28 n. 1-3, p. 74-83 | en_US |
dc.identifier.issn | 0303-6847 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173495 | - |
dc.description.abstract | The endothelial cells help to control the tone of the underlying vascular smooth muscle by releasing vasoactive factors. In physiological circumstances, the release of relaxing factors (nitric oxide and endothelium-derived hyperpolarizing factor) appears to predominate. However, in certain blood vessels (peripheral veins and large cerebral arteries), the normal endothelium has the propensity to release vasoconstrictor substances, among which are superoxide anion and thromboxane A 2; the release of these endothelium-derived vasoconstrictors may contribute to the autoregulatory processes. In most blood vessels, anoxic conditions initiate the release of an unidentified endothelium-dependent contracting fractor. Cultured endothelial cells, and blood vessels maintained under culture conditions for prolonged periods of time, release the vasoconstrictor peptide endothelin. A characteristic of vascular diseases is that the ability of the endothelial cells to release relaxing factor(s) is reduced, while the generation of contracting factor is maintained or enhanced. | en_US |
dc.language | eng | en_US |
dc.publisher | S Karger AG. The Journal's web site is located at http://www.karger.com/JVR | en_US |
dc.relation.ispartof | Blood Vessels | en_US |
dc.subject | anoxic conditions | - |
dc.subject | autoregulatory processes | - |
dc.subject | cultured endothelial cells | - |
dc.subject | cyclooxygenase | - |
dc.subject | EDCF | - |
dc.subject | endothelin | - |
dc.subject | endothelium-derived contractile factor(s) | - |
dc.subject | superoxide anion | - |
dc.subject | thromboxane A2 | - |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Anoxia - Physiopathology | en_US |
dc.subject.mesh | Endothelins - Physiology | en_US |
dc.subject.mesh | Endothelium, Vascular - Physiology | en_US |
dc.subject.mesh | Muscle Contraction - Physiology | en_US |
dc.subject.mesh | Muscle, Smooth, Vascular - Physiology | en_US |
dc.subject.mesh | Prostaglandin-Endoperoxide Synthases - Metabolism | en_US |
dc.title | Endothelium-dependent contractions | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Vanhoutte, PM:vanhoutt@hku.hk | en_US |
dc.identifier.authority | Vanhoutte, PM=rp00238 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 1900447 | - |
dc.identifier.scopus | eid_2-s2.0-0026078824 | en_US |
dc.identifier.volume | 28 | en_US |
dc.identifier.issue | 1-3 | en_US |
dc.identifier.spage | 74 | en_US |
dc.identifier.epage | 83 | en_US |
dc.identifier.isi | WOS:A1991FB33600011 | - |
dc.publisher.place | Switzerland | en_US |
dc.identifier.scopusauthorid | Vanhoutte, PM=7202304247 | en_US |
dc.identifier.scopusauthorid | Luscher, TF=18935805600 | en_US |
dc.identifier.scopusauthorid | Graser, T=7005581334 | en_US |
dc.identifier.issnl | 0303-6847 | - |