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Article: Premalignant vulvar disorders

TitlePremalignant vulvar disorders
Authors
Issue Date2000
PublisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/curobgyn
Citation
Current Obstetrics And Gynaecology, 2000, v. 10 n. 1, p. 12-17 How to Cite?
AbstractA number of premalignant conditions affect the vulva. This article considers vulvar intraepithelial neoplasia (VIN), vulvar Paget's disease and lichen sclerosus. The malignant potential of these uncommon conditions is difficult to accurately assess, but is reported to be up to 5% for VIN and lichen sclerosus. Vulvar Paget's disease is strongly associated with carcinoma - this may be underlying the vulvar lesion (in up to 20%) or a distant primary (in 20-30%). The management of VIN is primarily surgical, with a trend away from radical surgery towards more conservative wide local excision. The incidence of VIN is increasing, while the incidence of vulval cancer remains constant. The greatest increase in VIN is seen in younger women in whom there is a strong association with human papilloma virus (HPV) infection. Wide local excision of vulvar Paget's is recommended. There is a high recurrence rate for both of these conditions. Early referral for assessment and tailoring the management of these patients on an individual basis may help reduce long-term morbidity. The management of lichen sclerosus is mainly medical, with topical steroids used for symptom control. For all of these conditions long-term follow up is recommended in view of the risk of malignant transformation. (C) 2000 Harcourt Publishers Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/173243
ISSN
References

 

DC FieldValueLanguage
dc.contributor.authorAcheson, Nen_US
dc.contributor.authorGanesan, Ren_US
dc.contributor.authorChan, KKen_US
dc.date.accessioned2012-10-30T06:28:44Z-
dc.date.available2012-10-30T06:28:44Z-
dc.date.issued2000en_US
dc.identifier.citationCurrent Obstetrics And Gynaecology, 2000, v. 10 n. 1, p. 12-17en_US
dc.identifier.issn0957-5847en_US
dc.identifier.urihttp://hdl.handle.net/10722/173243-
dc.description.abstractA number of premalignant conditions affect the vulva. This article considers vulvar intraepithelial neoplasia (VIN), vulvar Paget's disease and lichen sclerosus. The malignant potential of these uncommon conditions is difficult to accurately assess, but is reported to be up to 5% for VIN and lichen sclerosus. Vulvar Paget's disease is strongly associated with carcinoma - this may be underlying the vulvar lesion (in up to 20%) or a distant primary (in 20-30%). The management of VIN is primarily surgical, with a trend away from radical surgery towards more conservative wide local excision. The incidence of VIN is increasing, while the incidence of vulval cancer remains constant. The greatest increase in VIN is seen in younger women in whom there is a strong association with human papilloma virus (HPV) infection. Wide local excision of vulvar Paget's is recommended. There is a high recurrence rate for both of these conditions. Early referral for assessment and tailoring the management of these patients on an individual basis may help reduce long-term morbidity. The management of lichen sclerosus is mainly medical, with topical steroids used for symptom control. For all of these conditions long-term follow up is recommended in view of the risk of malignant transformation. (C) 2000 Harcourt Publishers Ltd.en_US
dc.languageengen_US
dc.publisherChurchill Livingstone. The Journal's web site is located at http://www.elsevier.com/locate/curobgynen_US
dc.relation.ispartofCurrent Obstetrics and Gynaecologyen_US
dc.titlePremalignant vulvar disordersen_US
dc.typeArticleen_US
dc.identifier.emailChan, KK:kklchan@hkucc.hku.hken_US
dc.identifier.authorityChan, KK=rp00499en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1054/cuog.2000.0057en_US
dc.identifier.scopuseid_2-s2.0-0034086632en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034086632&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume10en_US
dc.identifier.issue1en_US
dc.identifier.spage12en_US
dc.identifier.epage17en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridAcheson, N=16479747100en_US
dc.identifier.scopusauthoridGanesan, R=7005438004en_US
dc.identifier.scopusauthoridChan, KK=8655666700en_US

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