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Article: Coculture with homologous oviductal cells improved the implantation of human embryos - A prospective randomized control trial

TitleCoculture with homologous oviductal cells improved the implantation of human embryos - A prospective randomized control trial
Authors
Issue Date1996
PublisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=1058-0468
Citation
Journal Of Assisted Reproduction And Genetics, 1996, v. 13 n. 10, p. 762-767 How to Cite?
AbstractPurpose: The efficacy of homologous oviductal cell coculture on the success of a human in vitro fertilization program was investigated in a prospective randomized control clinical trial. Methods and Results: One hundred eighty-one couples were randomized into the control and the coculture groups. Pronuclear-stage zygotes were either cultured in Earles' balanced salt solution supplemented with 15% preovulatory serum (control) or cultured with human oviductal cells (coculture) for 24 hr before embryo transfer. There was no difference in the age of the patients, indication for treatment, number of oocyte retrieved or fertilized, or number of embryo replaced between the two groups. The pregnancy rates per transfer for the control and the coculture group were 12.8 and 19.3%, respectively. The number of viable fetus was significantly higher (P < 0.01, chi-square test) in the coculture group (25/264) than in the control group (8/262). The coculture group also showed a higher multiple pregnancy rate, lower abortion rate, and more spare embryos suitable for cryopreservation.
Persistent Identifierhttp://hdl.handle.net/10722/173224
ISSN
2015 Impact Factor: 1.858
2015 SCImago Journal Rankings: 0.858
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYeung, WSBen_US
dc.contributor.authorLau, EYLen_US
dc.contributor.authorChan, STHen_US
dc.contributor.authorHo, PCen_US
dc.date.accessioned2012-10-30T06:28:37Z-
dc.date.available2012-10-30T06:28:37Z-
dc.date.issued1996en_US
dc.identifier.citationJournal Of Assisted Reproduction And Genetics, 1996, v. 13 n. 10, p. 762-767en_US
dc.identifier.issn1058-0468en_US
dc.identifier.urihttp://hdl.handle.net/10722/173224-
dc.description.abstractPurpose: The efficacy of homologous oviductal cell coculture on the success of a human in vitro fertilization program was investigated in a prospective randomized control clinical trial. Methods and Results: One hundred eighty-one couples were randomized into the control and the coculture groups. Pronuclear-stage zygotes were either cultured in Earles' balanced salt solution supplemented with 15% preovulatory serum (control) or cultured with human oviductal cells (coculture) for 24 hr before embryo transfer. There was no difference in the age of the patients, indication for treatment, number of oocyte retrieved or fertilized, or number of embryo replaced between the two groups. The pregnancy rates per transfer for the control and the coculture group were 12.8 and 19.3%, respectively. The number of viable fetus was significantly higher (P < 0.01, chi-square test) in the coculture group (25/264) than in the control group (8/262). The coculture group also showed a higher multiple pregnancy rate, lower abortion rate, and more spare embryos suitable for cryopreservation.en_US
dc.languageengen_US
dc.publisherSpringer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=1058-0468en_US
dc.relation.ispartofJournal of Assisted Reproduction and Geneticsen_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshCells, Cultureden_US
dc.subject.meshCoculture Techniquesen_US
dc.subject.meshEmbryo Transferen_US
dc.subject.meshFallopian Tubes - Metabolismen_US
dc.subject.meshFemaleen_US
dc.subject.meshFertilization In Vitro - Methodsen_US
dc.subject.meshFetal Viabilityen_US
dc.subject.meshHumansen_US
dc.subject.meshMicroscopy, Phase-Contrasten_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Outcomeen_US
dc.subject.meshPregnancy Rateen_US
dc.titleCoculture with homologous oviductal cells improved the implantation of human embryos - A prospective randomized control trialen_US
dc.typeArticleen_US
dc.identifier.emailYeung, WSB:wsbyeung@hkucc.hku.hken_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityYeung, WSB=rp00331en_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/BF02066494en_US
dc.identifier.pmid8986585-
dc.identifier.scopuseid_2-s2.0-0030458316en_US
dc.identifier.hkuros22749-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030458316&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume13en_US
dc.identifier.issue10en_US
dc.identifier.spage762en_US
dc.identifier.epage767en_US
dc.identifier.isiWOS:A1996VZ79500003-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridYeung, WSB=7102370745en_US
dc.identifier.scopusauthoridLau, EYL=7103086093en_US
dc.identifier.scopusauthoridChan, STH=24368283200en_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US

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