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Article: Diagnosis of early pregnancy by enzyme immunoassay of Schwangerschafts-protein 1

TitleDiagnosis of early pregnancy by enzyme immunoassay of Schwangerschafts-protein 1
Authors
Issue Date1988
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnstert
Citation
Fertility And Sterility, 1988, v. 49 n. 1, p. 76-80 How to Cite?
AbstractSerum Schwangerschafts-protein 1 (SP1) and beta subunit of human chorionic gonadotropin (β-hCG) were measured by enzyme immunoassay and radioimmunoassay, respectively, in the follicular phase and luteal phase of 50 human menopausal gonadotropin treatment cycles. SP1 could be detected in 63% of blood samples taken in the follicular phase up to the level of 1.56 μg/l. Using a cutoff level of 2 μg/l, SP1 could be used to diagnose pregnancy 16 to 25 days after the ovulating dose of hCG. The serum SP1 level is not affected by hCG injections and it can be used for diagnosis of pregnancy even when hCG has been given recently. SP1 also may be used as a prognostic indicator of the outcome of the pregnancy.
Persistent Identifierhttp://hdl.handle.net/10722/173128
ISSN
2015 Impact Factor: 4.426
2015 SCImago Journal Rankings: 2.156
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHo, PCen_US
dc.contributor.authorChan, SYWen_US
dc.contributor.authorTang, GWKen_US
dc.date.accessioned2012-10-30T06:28:05Z-
dc.date.available2012-10-30T06:28:05Z-
dc.date.issued1988en_US
dc.identifier.citationFertility And Sterility, 1988, v. 49 n. 1, p. 76-80en_US
dc.identifier.issn0015-0282en_US
dc.identifier.urihttp://hdl.handle.net/10722/173128-
dc.description.abstractSerum Schwangerschafts-protein 1 (SP1) and beta subunit of human chorionic gonadotropin (β-hCG) were measured by enzyme immunoassay and radioimmunoassay, respectively, in the follicular phase and luteal phase of 50 human menopausal gonadotropin treatment cycles. SP1 could be detected in 63% of blood samples taken in the follicular phase up to the level of 1.56 μg/l. Using a cutoff level of 2 μg/l, SP1 could be used to diagnose pregnancy 16 to 25 days after the ovulating dose of hCG. The serum SP1 level is not affected by hCG injections and it can be used for diagnosis of pregnancy even when hCG has been given recently. SP1 also may be used as a prognostic indicator of the outcome of the pregnancy.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/fertnsterten_US
dc.relation.ispartofFertility and Sterilityen_US
dc.subject.meshAbortion, Spontaneous - Blooden_US
dc.subject.meshChorionic Gonadotropin - Administration & Dosage - Blood - Pharmacologyen_US
dc.subject.meshChorionic Gonadotropin, Beta Subunit, Humanen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoenzyme Techniquesen_US
dc.subject.meshInjections, Intramuscularen_US
dc.subject.meshPeptide Fragments - Administration & Dosage - Blood - Pharmacologyen_US
dc.subject.meshPregnancy - Blooden_US
dc.subject.meshPregnancy Proteins - Analysisen_US
dc.subject.meshPregnancy-Specific Beta 1-Glycoproteins - Analysisen_US
dc.titleDiagnosis of early pregnancy by enzyme immunoassay of Schwangerschafts-protein 1en_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.emailTang, GWK:gwktang@hkucc.hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.identifier.authorityTang, GWK=rp00328en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2446931-
dc.identifier.scopuseid_2-s2.0-0023845275en_US
dc.identifier.volume49en_US
dc.identifier.issue1en_US
dc.identifier.spage76en_US
dc.identifier.epage80en_US
dc.identifier.isiWOS:A1988L735300013-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US
dc.identifier.scopusauthoridTang, GWK=7401633864en_US

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