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Article: Increased Factor VIII related antigen levels in hydatidiform molar pregnancy

TitleIncreased Factor VIII related antigen levels in hydatidiform molar pregnancy
Authors
Issue Date1984
Citation
Ircs Medical Science, 1984, v. 12 n. 2, p. 169-170 How to Cite?
AbstractSerum Factor VIII related antigen (Factor VIII R:Ag) levels were determined by the Laurell rocket immunoelectrophoresis in 32 patients with hydatidiform mole before evacuation of the uterus and in 272 normal pregnant women. The level of Factor VIII R:Ag was expressed as a percentage of a normal standard consisting of a pooled sera from 20 normal non-pregnant women. Factor VIII R:Ag levels in normal pregnancy increased with periods of gestation, reaching the highest level in the third trimester. The mean ± S.D. level of Factor VIII R:Ag in patients with hydatidiform mole (254% ± 76%) was significantly higher (P < 0.05) than those of the first and second trimesters of normal pregnancy (143% ± 46% and 187% ± 48%, respectively) and was similar to that of the third trimester (225% ± 73%). The increase in Factor VIII R:Ag levels in hydatidiform mole patients was probably related to the hypercoagulation state of pregnancy and chronic low-grade disseminated intravascular coagulation in molar pregnancy.
Persistent Identifierhttp://hdl.handle.net/10722/173078
ISSN

 

DC FieldValueLanguage
dc.contributor.authorChan, PHen_US
dc.contributor.authorChan, SYWen_US
dc.contributor.authorHo, PCen_US
dc.contributor.authorMa, HKen_US
dc.date.accessioned2012-10-30T06:27:51Z-
dc.date.available2012-10-30T06:27:51Z-
dc.date.issued1984en_US
dc.identifier.citationIrcs Medical Science, 1984, v. 12 n. 2, p. 169-170en_US
dc.identifier.issn0305-6651en_US
dc.identifier.urihttp://hdl.handle.net/10722/173078-
dc.description.abstractSerum Factor VIII related antigen (Factor VIII R:Ag) levels were determined by the Laurell rocket immunoelectrophoresis in 32 patients with hydatidiform mole before evacuation of the uterus and in 272 normal pregnant women. The level of Factor VIII R:Ag was expressed as a percentage of a normal standard consisting of a pooled sera from 20 normal non-pregnant women. Factor VIII R:Ag levels in normal pregnancy increased with periods of gestation, reaching the highest level in the third trimester. The mean ± S.D. level of Factor VIII R:Ag in patients with hydatidiform mole (254% ± 76%) was significantly higher (P < 0.05) than those of the first and second trimesters of normal pregnancy (143% ± 46% and 187% ± 48%, respectively) and was similar to that of the third trimester (225% ± 73%). The increase in Factor VIII R:Ag levels in hydatidiform mole patients was probably related to the hypercoagulation state of pregnancy and chronic low-grade disseminated intravascular coagulation in molar pregnancy.en_US
dc.languageengen_US
dc.relation.ispartofIRCS Medical Scienceen_US
dc.titleIncreased Factor VIII related antigen levels in hydatidiform molar pregnancyen_US
dc.typeArticleen_US
dc.identifier.emailHo, PC:pcho@hku.hken_US
dc.identifier.authorityHo, PC=rp00325en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0021333985en_US
dc.identifier.volume12en_US
dc.identifier.issue2en_US
dc.identifier.spage169en_US
dc.identifier.epage170en_US
dc.identifier.scopusauthoridChan, PH=7403497875en_US
dc.identifier.scopusauthoridChan, SYW=7404255960en_US
dc.identifier.scopusauthoridHo, PC=7402211440en_US
dc.identifier.scopusauthoridMa, HK=7403095603en_US

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