Article: Prospective randomized study of selective neck dissection versus observation for no neck of early tongue carcinoma

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TitleProspective randomized study of selective neck dissection versus observation for no neck of early tongue carcinoma
AuthorsYuen, APW3
Chiu, MH1
Tam, LC5
Lap, CT4
Wing, YC1
Ng, RWM3
Wei, WI3
Chi, KK2
Kwok, SB2
Wai, CY6
Lam, AKY7
Yuen, NWF5
TrendellSmith, NJ8
Yue, WC3
Wong, BYH3
Li, GKH3
Ho, ACW3
Wai, KH3
Sau, YW3
Yao, TJ3
KeywordsCarcinoma
Dissection
Neck
Randomized
Tongue
Issue Date2009
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
CitationHead And Neck, 2009, v. 31 n. 6, p. 765-772 [How to Cite?]
DOI: http://dx.doi.org/10.1002/hed.21033
AbstractBackground. There are controversies on the bene-fits of elective neck dissection (END) for oral tongue carcinoma. Method. This is a prospective randomized study of elective selective I, II, III neck dissection versus observation for N0 neck of stage I to II oral tongue carcinoma. There were 35 patients on the observation arm and 36 patients on the END arm. The main outcome assessment parameters are node-related mortality and disease-specific survival rate. Results. There were 11 patients in the observed arm and 2 patients in the END arm who developed nodal recurrence alone without associated local or distant recurrence. All 13 patients were salvaged, and no patient died of nodal recurrence. The 5-year disease-specific survival rate was 87% for the observation arm and was 89% for the END arm; the 2% difference was not significant. Conclusion. Observation may be an acceptable alternative to END if strict adherence to a cancer surveillance protocol is followed. © 2009 Wiley Periodicals, Inc.
ISSN1043-3074
2011 Impact Factor: 2.403
2011 SCImago Journal Rankings: 0.170
DOIhttp://dx.doi.org/10.1002/hed.21033
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorYuen, APW
dc.contributor.authorChiu, MH
dc.contributor.authorTam, LC
dc.contributor.authorLap, CT
dc.contributor.authorWing, YC
dc.contributor.authorNg, RWM
dc.contributor.authorWei, WI
dc.contributor.authorChi, KK
dc.contributor.authorKwok, SB
dc.contributor.authorWai, CY
dc.contributor.authorLam, AKY
dc.contributor.authorYuen, NWF
dc.contributor.authorTrendellSmith, NJ
dc.contributor.authorYue, WC
dc.contributor.authorWong, BYH
dc.contributor.authorLi, GKH
dc.contributor.authorHo, ACW
dc.contributor.authorWai, KH
dc.contributor.authorSau, YW
dc.contributor.authorYao, TJ
dc.date.accessioned2012-10-30T06:26:14Z
dc.date.available2012-10-30T06:26:14Z
dc.date.issued2009
dc.description.abstractBackground. There are controversies on the bene-fits of elective neck dissection (END) for oral tongue carcinoma. Method. This is a prospective randomized study of elective selective I, II, III neck dissection versus observation for N0 neck of stage I to II oral tongue carcinoma. There were 35 patients on the observation arm and 36 patients on the END arm. The main outcome assessment parameters are node-related mortality and disease-specific survival rate. Results. There were 11 patients in the observed arm and 2 patients in the END arm who developed nodal recurrence alone without associated local or distant recurrence. All 13 patients were salvaged, and no patient died of nodal recurrence. The 5-year disease-specific survival rate was 87% for the observation arm and was 89% for the END arm; the 2% difference was not significant. Conclusion. Observation may be an acceptable alternative to END if strict adherence to a cancer surveillance protocol is followed. © 2009 Wiley Periodicals, Inc.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationHead And Neck, 2009, v. 31 n. 6, p. 765-772 [How to Cite?]
DOI: http://dx.doi.org/10.1002/hed.21033
dc.identifier.doihttp://dx.doi.org/10.1002/hed.21033
dc.identifier.epage772
dc.identifier.issn1043-3074
2011 Impact Factor: 2.403
2011 SCImago Journal Rankings: 0.170
dc.identifier.issue6
dc.identifier.pmid19408291
dc.identifier.scopuseid_2-s2.0-67049100822
dc.identifier.spage765
dc.identifier.urihttp://hdl.handle.net/10722/172987
dc.identifier.volume31
dc.languageeng
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
dc.publisher.placeUnited States
dc.relation.ispartofHead and Neck
dc.relation.referencesReferences in Scopus
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 And Over
dc.subject.meshCarcinoma, Squamous Cell - Mortality - Pathology - Surgery - Therapy
dc.subject.meshChi-Square Distribution
dc.subject.meshDisease-Free Survival
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshHumans
dc.subject.meshKaplan-Meier Estimate
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshMonitoring, Physiologic - Methods
dc.subject.meshNeck Dissection - Methods
dc.subject.meshNeoplasm Recurrence, Local - Mortality - Pathology
dc.subject.meshNeoplasm Staging
dc.subject.meshObservation - Methods
dc.subject.meshPatient Selection
dc.subject.meshProspective Studies
dc.subject.meshReference Values
dc.subject.meshRisk Assessment
dc.subject.meshSurvival Analysis
dc.subject.meshTongue Neoplasms - Mortality - Pathology - Surgery - Therapy
dc.subject.meshTreatment Outcome
dc.subjectCarcinoma
dc.subjectDissection
dc.subjectNeck
dc.subjectRandomized
dc.subjectTongue
dc.titleProspective randomized study of selective neck dissection versus observation for no neck of early tongue carcinoma
dc.typeArticle
Author Affiliations
  1. Kwong Wah Hospital
  2. Yan Chai Hospital - Hong Kong
  3. The University of Hong Kong
  4. Queen Elizabeth Hospital Hong Kong
  5. United Christian Hospital Hong Kong
  6. Ruttonjee Hospital Hong Kong
  7. Griffith University
  8. Queen Mary Hospital Hong Kong