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Article: Liver transplantation in Asia: Past, present and future

TitleLiver transplantation in Asia: Past, present and future
Authors
Issue Date2009
PublisherAcademy of Medicine Singapore. The Journal's web site is located at http://www.annals.edu.sg
Citation
Annals Of The Academy Of Medicine Singapore, 2009, v. 38 n. 4, p. 322-331 How to Cite?
AbstractWith the technical advances and improvements in perioperative management and immunosuppressants, liver transplantation is the standard treatment for patients with end-stage liver diseases. In Asia, a shortage of deceased donor liver grafts is the universal problem to be faced with in all transplant centres. Many surgical innovations are then driven to counteract this problem. This review focuses on 3 issues that denote the development of liver transplantation in Asian countries. These include living donor liver transplantation (LDLT), split liver transplantation (SLT) and liver transplantation for hepatocellular carcinoma (HCC). Minimal graft weight, types of liver graft to donate and the inclusion of the middle hepatic vein with the graft are the main issues to be established in LDLT. The rapid growth and wide dissemination of LDLT has certainly alleviated the supply-and-demand problem of liver grafts in Asia. SLT is another attractive approach. Technical expertise, donor selection and graft allocation are the main determinants for its success. Liver transplantation plays a key role in the management of HCC in Asia. LDLT would be the main strategy in this aspect. The issue of extending the selection criteria for HCC patients for LDLT is still controversial. On the whole, future developments to increase the donor pool for the expanding recipient need in Asia would involve transplantation from non-heart beating donor and ABO incompatible transplantation.
Persistent Identifierhttp://hdl.handle.net/10722/172986
ISSN
2015 Impact Factor: 1.041
2015 SCImago Journal Rankings: 0.425
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, KKen_US
dc.contributor.authorLo, CMen_US
dc.date.accessioned2012-10-30T06:26:13Z-
dc.date.available2012-10-30T06:26:13Z-
dc.date.issued2009en_US
dc.identifier.citationAnnals Of The Academy Of Medicine Singapore, 2009, v. 38 n. 4, p. 322-331en_US
dc.identifier.issn0304-4602en_US
dc.identifier.urihttp://hdl.handle.net/10722/172986-
dc.description.abstractWith the technical advances and improvements in perioperative management and immunosuppressants, liver transplantation is the standard treatment for patients with end-stage liver diseases. In Asia, a shortage of deceased donor liver grafts is the universal problem to be faced with in all transplant centres. Many surgical innovations are then driven to counteract this problem. This review focuses on 3 issues that denote the development of liver transplantation in Asian countries. These include living donor liver transplantation (LDLT), split liver transplantation (SLT) and liver transplantation for hepatocellular carcinoma (HCC). Minimal graft weight, types of liver graft to donate and the inclusion of the middle hepatic vein with the graft are the main issues to be established in LDLT. The rapid growth and wide dissemination of LDLT has certainly alleviated the supply-and-demand problem of liver grafts in Asia. SLT is another attractive approach. Technical expertise, donor selection and graft allocation are the main determinants for its success. Liver transplantation plays a key role in the management of HCC in Asia. LDLT would be the main strategy in this aspect. The issue of extending the selection criteria for HCC patients for LDLT is still controversial. On the whole, future developments to increase the donor pool for the expanding recipient need in Asia would involve transplantation from non-heart beating donor and ABO incompatible transplantation.en_US
dc.languageengen_US
dc.publisherAcademy of Medicine Singapore. The Journal's web site is located at http://www.annals.edu.sgen_US
dc.relation.ispartofAnnals of the Academy of Medicine Singaporeen_US
dc.subject.meshAsiaen_US
dc.subject.meshCarcinoma, Hepatocellular - Surgeryen_US
dc.subject.meshHistory, 20Th Centuryen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Neoplasms - Surgeryen_US
dc.subject.meshLiver Transplantation - History - Methods - Trendsen_US
dc.subject.meshLiving Donorsen_US
dc.titleLiver transplantation in Asia: Past, present and futureen_US
dc.typeArticleen_US
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_US
dc.identifier.authorityLo, CM=rp00412en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.pmid19434335-
dc.identifier.scopuseid_2-s2.0-65749098005en_US
dc.identifier.hkuros164072-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-65749098005&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume38en_US
dc.identifier.issue4en_US
dc.identifier.spage322en_US
dc.identifier.epage331en_US
dc.identifier.isiWOS:000266184000006-
dc.publisher.placeSingaporeen_US
dc.identifier.scopusauthoridNg, KK=7403179075en_US
dc.identifier.scopusauthoridLo, CM=7401771672en_US

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