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- Publisher Website: 10.1038/ncpgasthep1204
- Scopus: eid_2-s2.0-51349161175
- PMID: 18628733
- WOS: WOS:000258829000007
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Article: Is radiofrequency ablation the treatment of choice for patients with small hepatocellular carcinoma?
Title | Is radiofrequency ablation the treatment of choice for patients with small hepatocellular carcinoma? |
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Authors | |
Issue Date | 2008 |
Publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ncpgasthep/ |
Citation | Nature Clinical Practice Gastroenterology And Hepatology, 2008, v. 5 n. 9, p. 492-493 How to Cite? |
Abstract | Liver resection is widely considered the mainstay of curative therapy for small hepatocellular carcinoma (HCC). Radiofrequency ablation (RFA) was initially developed as a treatment for small HCC in patients with considerable cirrhosis and inadequate liver function reserve for liver resection. However, in some centers, RFA is now used for small HCC, as an alternative to liver resection or even as the preferred treatment. This Practice Point commentary discusses the findings and limitations of a retrospective cohort study by Livraghi et al. that analyzed the outcomes of a group of patients with small, single HCC who underwent treatment with RFA. The authors reported a low major complication rate and a local complete response rate similar to that after resection. This commentary highlights the issues to consider when interpreting and generalizing these results, in particular that these findings need to be interpreted in the light of studies that suggest a high rate of local recurrence and incomplete histopathological response after RFA of small HCC. |
Persistent Identifier | http://hdl.handle.net/10722/172977 |
ISSN | 2011 Impact Factor: 5.333 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Poon, RTP | en_US |
dc.date.accessioned | 2012-10-30T06:26:10Z | - |
dc.date.available | 2012-10-30T06:26:10Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Nature Clinical Practice Gastroenterology And Hepatology, 2008, v. 5 n. 9, p. 492-493 | en_US |
dc.identifier.issn | 1743-4378 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/172977 | - |
dc.description.abstract | Liver resection is widely considered the mainstay of curative therapy for small hepatocellular carcinoma (HCC). Radiofrequency ablation (RFA) was initially developed as a treatment for small HCC in patients with considerable cirrhosis and inadequate liver function reserve for liver resection. However, in some centers, RFA is now used for small HCC, as an alternative to liver resection or even as the preferred treatment. This Practice Point commentary discusses the findings and limitations of a retrospective cohort study by Livraghi et al. that analyzed the outcomes of a group of patients with small, single HCC who underwent treatment with RFA. The authors reported a low major complication rate and a local complete response rate similar to that after resection. This commentary highlights the issues to consider when interpreting and generalizing these results, in particular that these findings need to be interpreted in the light of studies that suggest a high rate of local recurrence and incomplete histopathological response after RFA of small HCC. | en_US |
dc.language | eng | en_US |
dc.publisher | Nature Publishing Group. The Journal's web site is located at http://www.nature.com/ncpgasthep/ | en_US |
dc.relation.ispartof | Nature Clinical Practice Gastroenterology and Hepatology | en_US |
dc.title | Is radiofrequency ablation the treatment of choice for patients with small hepatocellular carcinoma? | en_US |
dc.type | Article | en_US |
dc.identifier.email | Poon, RTP: poontp@hkucc.hku.hk | en_US |
dc.identifier.authority | Poon, RTP=rp00446 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1038/ncpgasthep1204 | en_US |
dc.identifier.pmid | 18628733 | - |
dc.identifier.scopus | eid_2-s2.0-51349161175 | en_US |
dc.identifier.hkuros | 167148 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-51349161175&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.spage | 492 | en_US |
dc.identifier.epage | 493 | en_US |
dc.identifier.isi | WOS:000258829000007 | - |
dc.publisher.place | United Kingdom | en_US |
dc.identifier.scopusauthorid | Poon, RTP=7103097223 | en_US |
dc.identifier.issnl | 1743-4378 | - |