File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: MARS in the treatment of liver failure: Controversies and evidence

TitleMARS in the treatment of liver failure: Controversies and evidence
Authors
Issue Date2006
PublisherWichtig Editore srl. The Journal's web site is located at http://www.artificial-organs.com
Citation
International Journal Of Artificial Organs, 2006, v. 29 n. 7, p. 660-667 How to Cite?
AbstractMolecular Adsorbent Recirculation System (MARS) is a form of extracorporeal detoxification system used as an artificial liver support system. Numerous studies have been published on the topic, with the majority of them describing the capability of MARS in removing albumin-bound toxins and improving systemic hemodynamics. Whether such improvement could be translated into survival benefit is still uncertain, given the paucity of randomized controlled trials available. The outcome of patients receiving MARS treatment is difficult to analyze because liver failure patients constitute a heterogeneous population and different subgroups carry different prognoses. An evidence-based recommendation on the timing of MARS initiation is not available and currently MARS is usually commenced for hyperbilirubinemia or presence of complications of liver failure. MARS is in general a safe procedure, but there are still potential complications that need to be cautioned, along with various operative issues that are worth attention, The future prospects of MARS would rely on the completion of adequately powered randomized controlled trials. © Wichtig Editore, 2006.
Persistent Identifierhttp://hdl.handle.net/10722/172918
ISSN
2015 Impact Factor: 1.005
2015 SCImago Journal Rankings: 0.585
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChiu, Aen_US
dc.contributor.authorFan, STen_US
dc.date.accessioned2012-10-30T06:25:48Z-
dc.date.available2012-10-30T06:25:48Z-
dc.date.issued2006en_US
dc.identifier.citationInternational Journal Of Artificial Organs, 2006, v. 29 n. 7, p. 660-667en_US
dc.identifier.issn0391-3988en_US
dc.identifier.urihttp://hdl.handle.net/10722/172918-
dc.description.abstractMolecular Adsorbent Recirculation System (MARS) is a form of extracorporeal detoxification system used as an artificial liver support system. Numerous studies have been published on the topic, with the majority of them describing the capability of MARS in removing albumin-bound toxins and improving systemic hemodynamics. Whether such improvement could be translated into survival benefit is still uncertain, given the paucity of randomized controlled trials available. The outcome of patients receiving MARS treatment is difficult to analyze because liver failure patients constitute a heterogeneous population and different subgroups carry different prognoses. An evidence-based recommendation on the timing of MARS initiation is not available and currently MARS is usually commenced for hyperbilirubinemia or presence of complications of liver failure. MARS is in general a safe procedure, but there are still potential complications that need to be cautioned, along with various operative issues that are worth attention, The future prospects of MARS would rely on the completion of adequately powered randomized controlled trials. © Wichtig Editore, 2006.en_US
dc.languageengen_US
dc.publisherWichtig Editore srl. The Journal's web site is located at http://www.artificial-organs.comen_US
dc.relation.ispartofInternational Journal of Artificial Organsen_US
dc.subject.meshBilirubin - Blooden_US
dc.subject.meshChronic Diseaseen_US
dc.subject.meshEquipment Designen_US
dc.subject.meshHemofiltrationen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Failure - Mortality - Therapyen_US
dc.subject.meshLiver Failure, Acute - Therapyen_US
dc.subject.meshLiver, Artificial - Adverse Effectsen_US
dc.subject.meshRenal Dialysisen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleMARS in the treatment of liver failure: Controversies and evidenceen_US
dc.typeArticleen_US
dc.identifier.emailFan, ST: stfan@hku.hken_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid16874670en_US
dc.identifier.scopuseid_2-s2.0-33747615288en_US
dc.identifier.hkuros117703-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33747615288&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume29en_US
dc.identifier.issue7en_US
dc.identifier.spage660en_US
dc.identifier.epage667en_US
dc.identifier.isiWOS:000239585300003-
dc.publisher.placeItalyen_US
dc.identifier.scopusauthoridChiu, A=35721752900en_US
dc.identifier.scopusauthoridFan, ST=7402678224en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats