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Article: Liver transplantation for hepatocellular carcinoma: a report of 8 patients

TitleLiver transplantation for hepatocellular carcinoma: a report of 8 patients
Authors
Issue Date2000
Citation
Zhonghua Wai Ke Za Zhi [Chinese Journal Of Surgery], 2000, v. 38 n. 6, p. 415-417 How to Cite?
AbstractOBJECTIVE: To evaluate the feasibility of liver transplantation as a treatment for hepatocellular carcinoma (HCC). METHODS: From July 1995 to October 1998, eight liver cancer patients with cirrhosis underwent liver transplantation in Queen Mary Hospital. The liver grafts were obtained from 6 brainstem dead donors and 2 living donors. Five patients had known HCC and 3 had incidental tumor identified in the explanted liver. TNM staging: stage II (5 cases), stage III (2 cases) and stage IV a (1 case). After liver transplantation, the patients were followed up prospectively for a median of 36 months. Except for one patient who had preoperative chemotherapy, no anticancer treatment was given before and after transplantation. RESULTS: Three patients had acute rejection, 5 developed complication in early post transplantation. All were treated promptly and improved. One patient died one year after operation from septicemia. The recurrence-free survival rates of one and three years were 100% and 83.3%, respectively. CONCLUSIONS: Liver transplantation is a feasible method for treatment of HCC in selected patients. Living donor liver transplantation can overcome the problems of donor shortage and tumor growth while waiting for liver transplantation.
Persistent Identifierhttp://hdl.handle.net/10722/172861
ISSN
2015 SCImago Journal Rankings: 0.133

 

DC FieldValueLanguage
dc.contributor.authorZhang, Zen_US
dc.contributor.authorFan, Sen_US
dc.date.accessioned2012-10-30T06:25:23Z-
dc.date.available2012-10-30T06:25:23Z-
dc.date.issued2000en_US
dc.identifier.citationZhonghua Wai Ke Za Zhi [Chinese Journal Of Surgery], 2000, v. 38 n. 6, p. 415-417en_US
dc.identifier.issn0529-5815en_US
dc.identifier.urihttp://hdl.handle.net/10722/172861-
dc.description.abstractOBJECTIVE: To evaluate the feasibility of liver transplantation as a treatment for hepatocellular carcinoma (HCC). METHODS: From July 1995 to October 1998, eight liver cancer patients with cirrhosis underwent liver transplantation in Queen Mary Hospital. The liver grafts were obtained from 6 brainstem dead donors and 2 living donors. Five patients had known HCC and 3 had incidental tumor identified in the explanted liver. TNM staging: stage II (5 cases), stage III (2 cases) and stage IV a (1 case). After liver transplantation, the patients were followed up prospectively for a median of 36 months. Except for one patient who had preoperative chemotherapy, no anticancer treatment was given before and after transplantation. RESULTS: Three patients had acute rejection, 5 developed complication in early post transplantation. All were treated promptly and improved. One patient died one year after operation from septicemia. The recurrence-free survival rates of one and three years were 100% and 83.3%, respectively. CONCLUSIONS: Liver transplantation is a feasible method for treatment of HCC in selected patients. Living donor liver transplantation can overcome the problems of donor shortage and tumor growth while waiting for liver transplantation.en_US
dc.languageengen_US
dc.relation.ispartofZhonghua wai ke za zhi [Chinese journal of surgery]en_US
dc.subject.meshAdulten_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver Cirrhosis - Complicationsen_US
dc.subject.meshLiver Neoplasms - Complications - Mortality - Surgeryen_US
dc.subject.meshLiver Transplantationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTissue Donorsen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleLiver transplantation for hepatocellular carcinoma: a report of 8 patientsen_US
dc.typeArticleen_US
dc.identifier.emailFan, S: stfan@hku.hken_US
dc.identifier.authorityFan, S=rp00355en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid11832071-
dc.identifier.scopuseid_2-s2.0-13444256482en_US
dc.identifier.volume38en_US
dc.identifier.issue6en_US
dc.identifier.spage415en_US
dc.identifier.epage417en_US
dc.identifier.scopusauthoridZhang, Z=8574700400en_US
dc.identifier.scopusauthoridFan, S=7402678224en_US

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