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Article: Prediction of the severity of acute pancreatitis

TitlePrediction of the severity of acute pancreatitis
Authors
Issue Date1993
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjsurg
Citation
American Journal Of Surgery, 1993, v. 166 n. 3, p. 262-269 How to Cite?
AbstractWe conducted a prospective study to validate our previous finding that serum urea and plasma glucose levels on admission could predict the outcome of acute pancreatitis. Forty-two (24%) of 176 patients developed complications related to the attack of acute pancreatitis and were classified as having severe disease. By logistic regression analysis of 17 admission parameters, serum urea and plasma glucose levels were again the factors with independent significance in defining the outcome. By adopting the same cutoff levels as in our previous study (serum urea level greater than 7.4 mmol/L and plasma glucose level greater than 11.0 mmol/L), and the presence of either factor above the cutoff level as indicative of severe disease, the sensitivity of prediction was 79%, specificity 67%, and overall accuracy 70%. All the deaths were correctly predicted by this urea/glucose criteria. The overall accuracy was also found to be comparable with those of the APACHE II (cutoff level greater than II) and Ranson's scoring systems. We conclude that the simple prognostic criteria for acute pancreatitis were validated; these criteria have the potential to stratify risk rapidly at the time of admission for patients who might benefit from an aggressive interventional protocol.
Persistent Identifierhttp://hdl.handle.net/10722/172696
ISSN
2015 Impact Factor: 2.403
2015 SCImago Journal Rankings: 1.286
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorFan, STen_HK
dc.contributor.authorLai, ECSen_HK
dc.contributor.authorMok, FPTen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorZheng, SSen_HK
dc.contributor.authorWong, Jen_HK
dc.contributor.authorRanson, JHCen_HK
dc.date.accessioned2012-10-30T06:24:21Z-
dc.date.available2012-10-30T06:24:21Z-
dc.date.issued1993en_HK
dc.identifier.citationAmerican Journal Of Surgery, 1993, v. 166 n. 3, p. 262-269en_HK
dc.identifier.issn0002-9610en_HK
dc.identifier.urihttp://hdl.handle.net/10722/172696-
dc.description.abstractWe conducted a prospective study to validate our previous finding that serum urea and plasma glucose levels on admission could predict the outcome of acute pancreatitis. Forty-two (24%) of 176 patients developed complications related to the attack of acute pancreatitis and were classified as having severe disease. By logistic regression analysis of 17 admission parameters, serum urea and plasma glucose levels were again the factors with independent significance in defining the outcome. By adopting the same cutoff levels as in our previous study (serum urea level greater than 7.4 mmol/L and plasma glucose level greater than 11.0 mmol/L), and the presence of either factor above the cutoff level as indicative of severe disease, the sensitivity of prediction was 79%, specificity 67%, and overall accuracy 70%. All the deaths were correctly predicted by this urea/glucose criteria. The overall accuracy was also found to be comparable with those of the APACHE II (cutoff level greater than II) and Ranson's scoring systems. We conclude that the simple prognostic criteria for acute pancreatitis were validated; these criteria have the potential to stratify risk rapidly at the time of admission for patients who might benefit from an aggressive interventional protocol.en_HK
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/amjsurgen_HK
dc.relation.ispartofAmerican Journal of Surgeryen_HK
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshBlood Glucose - Analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPancreatitis - Blood - Mortalityen_US
dc.subject.meshPredictive Value Of Testsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSensitivity And Specificityen_US
dc.subject.meshSeverity Of Illness Indexen_US
dc.subject.meshUrea - Blooden_US
dc.titlePrediction of the severity of acute pancreatitisen_HK
dc.typeArticleen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailWong, J: jwong@hkucc.hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityWong, J=rp00322en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0002-9610(05)80970-5-
dc.identifier.pmid8368436-
dc.identifier.scopuseid_2-s2.0-0027764458en_HK
dc.identifier.volume166en_HK
dc.identifier.issue3en_HK
dc.identifier.spage262en_HK
dc.identifier.epage269en_HK
dc.identifier.isiWOS:A1993LX26900006-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridLai, ECS=36932159600en_HK
dc.identifier.scopusauthoridMok, FPT=6603786245en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridZheng, SS=23500759400en_HK
dc.identifier.scopusauthoridWong, J=8049324500en_HK
dc.identifier.scopusauthoridRanson, JHC=7006188342en_HK

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