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Article: Squamous cell carcinoma of the hypopharynx - Analysis of treatment results

TitleSquamous cell carcinoma of the hypopharynx - Analysis of treatment results
Authors
Issue Date1993
PublisherJohn Wiley & Sons, Inc.. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
Citation
Head And Neck, 1993, v. 15 n. 5, p. 405-412 How to Cite?
AbstractThe results of surgical treatment and causes of failure in 109 patients with squamous cell carcinoma of the hypopharynx were analyzed. The 5-year survival was significantly related to the stage of the disease (stage I, 74%; stage II, 63%; stage III, 32%; and stage IV, 14%) and the preoperative nodal staging (N0, 57%; N1, 28%; N2, 6%; and N3, 0%), but not related to the extent of tumor resection. The local control rate was 86% and the majority of the local recurrences occurred at the upper resection margin. There was no significant difference in the local recurrence rate between those patients who had pharyngolaryngoesophagectomy and those who had pharyngolaryngectomy. However, the resection-associated complications (bleeding, cardiac arrhythmia, pulmonary complications) were more frequent when total esophagectomy was performed. Reconstruction-associated complications such as wound infection and anastomotic leakage occurred less often after gastric pull-up reconstruction as compared with the use of myocutaneous flap, but was associated with more serious outcome after pharyngogastric anastomosis. Thirty-seven patients (34%) had neck node recurrences and these were significantly related to the preoperative nodal staging (N0, 20%; N1, 37%; N2, 48%; and N3, 83%). Additional primary cancers occurred in 17% of the patients and was a significant cause of death in those patients who survived more than 2 years.
Persistent Identifierhttp://hdl.handle.net/10722/172692
ISSN
2014 SCImago Journal Rankings: 0.123
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChiu Ming Hoen_US
dc.contributor.authorKam Hing Lamen_US
dc.contributor.authorIgnace Wei, Wen_US
dc.contributor.authorPo Wing Yuenen_US
dc.contributor.authorLai Kun Lamen_US
dc.date.accessioned2012-10-30T06:24:19Z-
dc.date.available2012-10-30T06:24:19Z-
dc.date.issued1993en_US
dc.identifier.citationHead And Neck, 1993, v. 15 n. 5, p. 405-412en_US
dc.identifier.issn0148-6403en_US
dc.identifier.urihttp://hdl.handle.net/10722/172692-
dc.description.abstractThe results of surgical treatment and causes of failure in 109 patients with squamous cell carcinoma of the hypopharynx were analyzed. The 5-year survival was significantly related to the stage of the disease (stage I, 74%; stage II, 63%; stage III, 32%; and stage IV, 14%) and the preoperative nodal staging (N0, 57%; N1, 28%; N2, 6%; and N3, 0%), but not related to the extent of tumor resection. The local control rate was 86% and the majority of the local recurrences occurred at the upper resection margin. There was no significant difference in the local recurrence rate between those patients who had pharyngolaryngoesophagectomy and those who had pharyngolaryngectomy. However, the resection-associated complications (bleeding, cardiac arrhythmia, pulmonary complications) were more frequent when total esophagectomy was performed. Reconstruction-associated complications such as wound infection and anastomotic leakage occurred less often after gastric pull-up reconstruction as compared with the use of myocutaneous flap, but was associated with more serious outcome after pharyngogastric anastomosis. Thirty-seven patients (34%) had neck node recurrences and these were significantly related to the preoperative nodal staging (N0, 20%; N1, 37%; N2, 48%; and N3, 83%). Additional primary cancers occurred in 17% of the patients and was a significant cause of death in those patients who survived more than 2 years.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc.. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137en_US
dc.relation.ispartofHead and Necken_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshCarcinoma, Squamous Cell - Pathology - Secondary - Surgeryen_US
dc.subject.meshCombined Modality Therapyen_US
dc.subject.meshEsophagectomy - Adverse Effects - Methodsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshHypopharyngeal Neoplasms - Pathology - Surgeryen_US
dc.subject.meshLaryngectomy - Adverse Effects - Methodsen_US
dc.subject.meshLymphatic Metastasisen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeck Dissection - Adverse Effectsen_US
dc.subject.meshNeoplasm Recurrence, Localen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshNeoplasms, Multiple Primary - Pathologyen_US
dc.subject.meshPharyngectomy - Adverse Effects - Methodsen_US
dc.subject.meshSurgical Flaps - Adverse Effects - Methodsen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshTreatment Failureen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleSquamous cell carcinoma of the hypopharynx - Analysis of treatment resultsen_US
dc.typeArticleen_US
dc.identifier.emailIgnace Wei, W: hrmswwi@hku.hken_US
dc.identifier.authorityIgnace Wei, W=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/hed.2880150507-
dc.identifier.pmid8407312-
dc.identifier.scopuseid_2-s2.0-0027268208en_US
dc.identifier.volume15en_US
dc.identifier.issue5en_US
dc.identifier.spage405en_US
dc.identifier.epage412en_US
dc.identifier.isiWOS:A1993LR99200006-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChiu Ming Ho=7409955650en_US
dc.identifier.scopusauthoridKam Hing Lam=7409839457en_US
dc.identifier.scopusauthoridIgnace Wei, W=7403321552en_US
dc.identifier.scopusauthoridPo Wing Yuen=7409559704en_US
dc.identifier.scopusauthoridLai Kun Lam=7409733932en_US

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