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Article: Fiberoptic endoscopic examination and biopsy in determining the extent of nasopharyngeal carcinoma

TitleFiberoptic endoscopic examination and biopsy in determining the extent of nasopharyngeal carcinoma
Authors
Issue Date1989
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 1989, v. 64 n. 9, p. 1838-1842 How to Cite?
AbstractThis is a prospective study on the use of flexible endoscope and multiple biopsies in the assessment of nasopharyngeal carcinoma in 72 patients. This study confirmed the presence of submucosal growth pattern in nasopharyngeal carcinoma and this occurred in 13.8% of patients. Occult microscopic extension of tumor not detectable by fiberoptic endoscopy occurred in another 51.4% of patients. It has also been shown that multiple biopsy is superior to clinical examination in evaluating the extent of disease in nasopharyngeal carcinoma. Multiple biopsies are suggested for the early detection of nasopharyngeal carcinoma in high-risk cases. Although the better-defined tumor extent does not currently influence the treatment policy of nasopharyngeal carcinoma, and it is too early to assess its prognostic significance, it betters our understanding of the behavior of this tumor. Future analysis in correlation with long-term follow-up data may help to improve the stage classification systems and treatment strategy.
Persistent Identifierhttp://hdl.handle.net/10722/172597
ISSN
2015 Impact Factor: 5.649
2015 SCImago Journal Rankings: 3.188
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSham, JSTen_US
dc.contributor.authorWei, WIen_US
dc.contributor.authorKwan, WHen_US
dc.contributor.authorChan, CWen_US
dc.contributor.authorChoi, PHKen_US
dc.contributor.authorChoy, Den_US
dc.date.accessioned2012-10-30T06:23:40Z-
dc.date.available2012-10-30T06:23:40Z-
dc.date.issued1989en_US
dc.identifier.citationCancer, 1989, v. 64 n. 9, p. 1838-1842en_US
dc.identifier.issn0008-543Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/172597-
dc.description.abstractThis is a prospective study on the use of flexible endoscope and multiple biopsies in the assessment of nasopharyngeal carcinoma in 72 patients. This study confirmed the presence of submucosal growth pattern in nasopharyngeal carcinoma and this occurred in 13.8% of patients. Occult microscopic extension of tumor not detectable by fiberoptic endoscopy occurred in another 51.4% of patients. It has also been shown that multiple biopsy is superior to clinical examination in evaluating the extent of disease in nasopharyngeal carcinoma. Multiple biopsies are suggested for the early detection of nasopharyngeal carcinoma in high-risk cases. Although the better-defined tumor extent does not currently influence the treatment policy of nasopharyngeal carcinoma, and it is too early to assess its prognostic significance, it betters our understanding of the behavior of this tumor. Future analysis in correlation with long-term follow-up data may help to improve the stage classification systems and treatment strategy.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_US
dc.relation.ispartofCanceren_US
dc.subject.meshBiopsyen_US
dc.subject.meshCarcinoma - Pathologyen_US
dc.subject.meshEndoscopyen_US
dc.subject.meshFalse Positive Reactionsen_US
dc.subject.meshFiber Optic Technologyen_US
dc.subject.meshHumansen_US
dc.subject.meshNasopharyngeal Neoplasms - Pathologyen_US
dc.subject.meshNeoplasm Invasivenessen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshProspective Studiesen_US
dc.titleFiberoptic endoscopic examination and biopsy in determining the extent of nasopharyngeal carcinomaen_US
dc.typeArticleen_US
dc.identifier.emailWei, WI: hrmswwi@hku.hken_US
dc.identifier.authorityWei, WI=rp00323en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/1097-0142(19891101)64:9<1838::AID-CNCR2820640914>3.0.CO;2-C-
dc.identifier.pmid2790697en_US
dc.identifier.scopuseid_2-s2.0-0024435211en_US
dc.identifier.volume64en_US
dc.identifier.issue9en_US
dc.identifier.spage1838en_US
dc.identifier.epage1842en_US
dc.identifier.isiWOS:A1989AV83300013-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridSham, JST=7101655565en_US
dc.identifier.scopusauthoridWei, WI=7403321552en_US
dc.identifier.scopusauthoridKwan, WH=7006610872en_US
dc.identifier.scopusauthoridChan, CW=7404813871en_US
dc.identifier.scopusauthoridChoi, PHK=7102909162en_US
dc.identifier.scopusauthoridChoy, D=7102939127en_US

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